Home > Pulmonology > NLC 2022 > Respiratory Disease and Reproduction > PRO-ART study: unravelling the link between asthma and subfertility

PRO-ART study: unravelling the link between asthma and subfertility

Presented By
Dr Anne Hansen, Copenhagen University Hospital, Denmark
Conference
NLC 2022
Trial
Phase 2, PRO-ART
Doi
https://doi.org/10.55788/1c4b35e9
The association between asthma and decreased fertility is currently being investigated in the PRO-ART study. The outcomes are expected to provide insights into the underlying mechanism and help to increase our understanding of this complex relationship. Asthma and sub-/infertility are among the most common chronic disorders in young adults [1]. Moreover, women with asthma seem to experience a prolonged time of unwanted non-conception [2]. Despite a possible association between asthma and decreased fertility, the underlying mechanisms are presently unknown. Possibly, the asthma-associated systemic inflammation may affect the reproductive organs and/or the germ cells thereby reducing fertility. The primary objective addressed in the PRO-ART study is to investigate whether systemic treatment with omalizumab (aimed at controlling systemic asthma-related inflammation as well as at improving asthma control) may improve the pregnancy rate/outcomes in women...


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