Home > Neurology > MS Virtual 2020 > Miscellaneous Topics > Cardiovascular risk factors may contribute to brain atrophy in MS patients

Cardiovascular risk factors may contribute to brain atrophy in MS patients

Conference
MS Virtual 2020
The presence of cardiovascular (CV) risk factors is associated with brain atrophy in MS patients ≤50 years, who are unlikely to have small vessel disease. An Italian cross-sectional observational study suggests CV risk factors have synergistic effects in MS [1]. The impact of CV risk factors on T2 hyperintense lesion volume and brain atrophy in MS patients aged ≤50 years was evaluated in 124 MS patients (relapsing-remitting MS, n=79; progressive MS, n=45) and 95 matched healthy controls. Participants underwent a complete neurological assessment and brain 3D T2-weighted and FLAIR MRI, as well as 3D T1-weighted MRI. Assessed traditional CV risk factors were smoking ≥5 pack-years, hypertension, dyslipidaemia, and (pre-)diabetes. More stringent cut-offs were also assessed: smoking ≥10 pack-years, and hypertension, dyslipidaemia, or diabetes while on medication. Of the 124 MS patients, 48 had 1 traditional CV risk factor, 15 had 2 or more. Of 95 healthy control...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on