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Age and EDSS are risk factors for severe COVID-19

MS Virtual 2020
Cohort study, COVISEP
In an observational French cohort study, EDSS and age were independent risk factors for severe COVID-19, while immunomodulating disease-modifying treatment (DMT) was independently associated with lower COVID-19 severity [1]. There was no association between immunosuppressive therapies and severity of COVID-19. The study cohort (COVISEP registry) that was analysed included 405 MS patients with confirmed or highly suspected SARS-CoV-2 infection between 1 March 2020 and 14 July 2020. Included were patients who met at least one of the following criteria: biologically confirmed COVID-19 diagnosis based on SARS-CoV-2 RT-PCR positivity; typical thoracic CT abnormalities (ground-glass opacities) in epidemic areas; sudden-onset anosmia or ageusia in the absence of rhinitis or nasal obstruction; or typical symptoms (triad associating cough, fever, asthenia) in the epidemic zone of COVID-19. Mean age was 44.7 year...

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