Home > Neurology > EAN 2020 > Stroke > Thrombus location and length predictors of early neurological deterioration

Thrombus location and length predictors of early neurological deterioration

Presented By
Dr Pierre Seners, Université Paris Descartes, France
Conference
EAN 2020
Trial
MINOR-STROKE
A large retrospective observational study in patients with minor strokes with large vessel occlusion found that thrombus location and length are strong predictors of early neurological deterioration (END) [1]. This may help to select the best candidates for additional endovascular therapy. Researchers from Paris, France conducted the multicentre observational study MINOR-STROKE in which they included 721 patients with intravenous thrombolysis-treated minor strokes (NIH Stroke Scale/Score [NIHSS] ≤5) with large vessel occlusion intended for intravenous thrombolysis alone, including those patients who eventually received thrombectomy because of END. END was defined as a ≥4-point NIHSS increase within 24 hours after admission. Mean age of participants was 70 years, median NIHSS was 3. Occlusion was located in the internal carotid artery (ICA)-T/L in 3%, in the tandem cervical ICA+middle cerebral artery in 10%, in the proximal M1 in 7%, in the distal M1 in 21%...


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