Home > Neurology > EAN 2020 > Stroke > Benefits of statins to prevent stroke outweigh risks

Benefits of statins to prevent stroke outweigh risks

Presented By
Dr Ammad Ishfaq, Zeenat Qureshi Stroke Institute, USA
Conference
EAN 2020
The benefits of lipid-lowering therapy in the prevention of ischaemic stroke greatly exceed the risk of intracerebral haemorrhage (ICH) that may be associated with statins. This conclusion is based on the outcomes of a new meta-analysis of 19 clinical studies [1]. The association between statins and intracerebral haemorrhage risk is still a matter of controversy. A new review and meta-analysis assessed the safety of statins by weighing risks and benefits in terms of cerebral haemorrhagic and ischaemic events. Included were 19 randomised and non-randomised studies with a total of 35,842 patients who had a history of cardiovascular or cerebrovascular events and had been treated with statins. The primary endpoint was ICH; secondary endpoints were ischaemic stroke and transient ischaemic attack (TIA). The results could not show a significant association between the risk of combined primary and secondary ICH and statin use (RR 1.03; 95% CI 0.85-1.08). Ho...


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