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Renal denervation better than sham for blood pressure

Presented By
Prof. M. Böhm, Saarland University Medical Center, Germany
Conference
ACC 2020
Trial
SPYRAL PIVOTAL - SPYRAL HTN-OFF MED
The SPYRAL PIVOTAL - SPYRAL HTN-OFF MED trial showed that renal denervation was superior to a sham procedure at reducing blood pressure in patients with uncontrolled high blood pressure at 3 months follow-up. Prof. Michael Böhm (Saarland University Medical Center, Germany) presented the international, prospective, single-blinded, sham-controlled trial, which was designed to assess the efficacy of renal denervation in the absence of antihypertensive medications [1]. The findings were simultaneously published in The Lancet [2]. This trial was instigated based on observational data suggesting that catheter-based renal denervation significantly reduced blood pressure. Following a positive pilot trial, the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED trial was powered to evaluate the efficacy of catheter-based renal den...


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