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Infusion of ethanol in the vein of Marshall for persistent AF

Presented By
Dr M. Valderrabano, Baylor College of Medicine, USA
Conference
ACC 2020
Trial
VENUS
The infusion of ethanol via the vein of Marshall (VOM), coupled with catheter ablation, leads to improved outcomes for patients with persistent atrial fibrillation (AF). Presented by Dr Miguel Valderrabano (Baylor College of Medicine, USA), the VENUS trial addressed the challenge of treating persistent AF, which is limited by the imperfect success of catheter ablation procedures, and the consequent need for repeat procedures [1]. The investigators hypothesised that by ablating AF triggers in the VOM through retrograde ethanol infusion, coupled with a catheter ablation approach, the restoration of normal rhythm could be achieved in more patients with persistent AF. Participants (n=343) with symptomatic persistent AF and refractory to at least 1 anti-arrhythmic agent were randomised to receive either catheter ablation alone (n=158) or catheter ablat...


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