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Novel use of ivabradine in reversible cardiomyopathy

Presented By
Dr Eric Torkildsen, Lehigh Valley Health Network, USA
ACC 2021
Ivabradine may reduce the risk of tachycardia-induced cardiomyopathy when used in refractory cases of tachycardia, as was suggested by findings from a case report [1]. Paragangliomas are rare tumours that result in persistent tachycardia and hypertension. Dr Eric Torkildsen (Lehigh Valley Health Network, PA, USA) shared a case report of a 62-year-old man with a history of metastatic hereditary paraganglioma, non-ischaemic cardiomyopathy with recovered ejection fraction, and recent pericardial effusion, who presented with worsening dyspnoea and sinus tachycardia. Echocardiographic findings included global hypokinesis, no evidence of re-accumulation of pericardial fluid, and a reduced ejection fraction of 20–25%. Angiographic findings demonstrated non-obstructive disease. Based on these findings, the patient was diagnosed with a hyperadrenergic state secondary to the hereditary paraganglioma. Management with metoprolol succinate, phenoxybenzami...

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