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Ablation-based rhythm control as effective as rate control in AF and HF

Presented By
Prof. Anthony Tang, University of Ottawa, Canada
Conference
ACC 2021
Trial
RAFT-AF
In patients with both atrial fibrillation (AF) and heart failure (HF), ablation-based rhythm control did not significantly reduce all-cause mortality or HF events when compared with rate control [1]. While catheter ablation offers an alternative to achieving rhythm control and resolving AF, no long-term studies have yet examined its effect on mortality and hospitalisations for HF. To address this gap, the RAFT-AF trial (NCT01420393) used a prospective, randomised, open-label, blinded endpoint (PROBE) design to compare catheter ablation-based AF rhythm control with rate control in participants diagnosed with both HF (stratified for reduced left ventricular ejection fraction [LVEF] of ≤45% or a preserved LVEF of >45%) and AF on the composite endpoint of all-cause mortality or HF events. An HF event was defined as admission...


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