Home > Rheumatology > EULAR 2022 > What Is Hot in Osteoarthritis? > Body mass index increase associated with structural changes in knee OA

Body mass index increase associated with structural changes in knee OA

Presented By
Dr Zubeyir Salis, University of New South Wales, Australia
Conference
EULAR 2022
Doi
https://doi.org/10.55788/bb380984
Both the incidence and structural defects of knee osteoarthritis (OA) can be slowed down by a reduction of the body mass index (BMI). Even a moderate weight loss is beneficial in this respect. Obesity is a known risk factor for OA and is associated with progression of knee OA. “But what we don’t know is whether weight loss is associated with a decreased incidence of knee OA in men and decreased progression of knee OA in men and women,” Dr Zubeyir Salis explained (University of New South Wales, Australia). Therefore, his study aimed to define the association between change in weight and the incidence and progression of radiographic knee OA [1]. Scores from knee radiographs at baseline and at 4 to 5 years of follow-up were obtained from 3 independent data sets (2 from the USA and 1 from the Netherlands). The exposure of interest was the change in BMI from baseline to 4 to 5 years of follow-up. To investigate the incidence of structural defec...


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