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Novel disease-specific scale confirms huge impact of fatigue

Presented By
Marion Azoulai, Carenity, France
ECF 2020
A real-world study in US adults with relapsing multiple sclerosis (MS) confirmed that fatigue has a huge impact on day-to-day functioning in most patients with relapsing MS. Fatigue increases with symptom exacerbation, depression, sleep disorders, and pain. The Fatigue Symptoms and Impacts Questionnaire-Relapsing Multiple Sclerosis (FSIQ-RMS) is a novel MS-specific assessment that can advance the understanding and management of fatigue. Fatigue is defined by subjective experience and measured via patient-reported outcome (PRO) instruments. PRO tools that are MS-specific can improve understanding of MS fatigue and its impact, improving its clinical management. However, currently available PROs that assess MS-related fatigue do not meet instrument development and psychometric property requirements based on current guidelines. The FSIQ-RMS is a novel MS-specific PRO instrument, which was developed to assess both fatigue in patients with relapsing MS a...

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