At ECTRIMS this year in Stockholm, about 7,000 MS specialists, neurologists, researchers, healthcare professionals gathered to present new data and exchange ideas and experiences in elucidating causes and mechanisms of MS, the genetics of this disease, new diagnostic criteria and methods, the broadening spectrum of related CNS immune disorders (NMOSD), advances in MR imaging, and fluid phase biomarkers. As always management issues were discussed extensively and data from clinical trials of new drugs were presented.
This summary attempts to identify and review the highlights of the congress.
I hope you will find this interesting reading.
Best wishes
Hans-Peter Hartung
Biography
Prof. Hartung has been Chair of the Department of Neurology at Hein-rich-Heine-University in Düsseldorf since 2001. He is also Director of the Center of Neuropsychiatry and the Department of Conservative Medicine at University Hospital Düsseldorf.
He studied medicine at the Universities of Düsseldorf, Glasgow, Oxford, and London. After graduation he served an immunology fellowship at the University of Mainz.
Prof. Hartung’s clinical and translational research interests are in the field of basic and clinical neuroimmunology and in particular multiple sclerosis and immune neuropathies. He has been involved as steering committee member in multiple clinical trials of new drugs for the treatment of multiple sclerosis, Guillain-Barre syndrome, and chronic inflammatory demyelinating polyneuropathy.
Prof. Hartung is a former President of ECTRIMS.
Conflict of Interest Statement:Hans-Peter Hartung has received fees for consulting, speaking, and serving on steering committees from Bayer Healthcare, Biogen, GeNeuro, MedImmune, Merck, Novartis, Opexa, Receptos Celgene, Roche, Sanofi Genzyme, CSL Behring, Octapharma, and Teva, with approval by the Rector of Heinrich-Heine-University.
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Table of Contents: ECTRIMS 2019
Featured articles
Towards a Comprehensive Assessment of MS Course
Cognitive assessment in MS
Late-breaking: Role for CSF markers in autoimmune astrocytopathies
Targeted therapies for NMOSD in development
Monitoring and Treatment of Progressive MS
Challenges in diagnosing and treating progressive MS
Risk factors for conversion to secondary progressive MS
Transplantation of autologous mesenchymal stem cells
Sustained reduction in disability progression with ocrelizumab
Late-breaking: Myelin-peptide coupled red blood cells
Optimising Long-Term Benefit of MS Treatment
Induction therapy over treatment escalation
Treatment escalation over induction therapy
Influence of age on disease progression
Exposure to DMTs reduces disability progression
Predicting long-term sustained disability progression
Treatment response scoring systems to assess long term prognosis
Safety Assessment in the Post-Approval Phase
Use of clinical registries in phase 4 of DMT
Genes, environment, and safety monitoring in using registries
Risk of hypogammaglobulinemia and rituximab
Determinants of outcomes for natalizumab-associated PML
Serum immunoglobulin levels and risk of serious infections
EAN guideline on palliative care
Pregnancy in the Treatment Era
The maternal perspective: when to stop/resume treatment and risks for progression
Foetal/child perspective: risks related to drug exposure and breastfeeding
Patient awareness about family planning represents a major knowledge gap
Late-breaking: Continuation of natalizumab or interruption during pregnancy
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