Long-term data confirm superiority of inter-hospital transport for primary PCI vs fibrinolysis

Patients with ST-segment elevation myocardial infarction (STEMI) who are transferred to the closest available invasive centre capable of primary percutaneous coronary intervention (pPCI), experience better outcomes than patients who are given fibrinolysis in their local facility. This was already demonstrated in 2003 and has been confirmed again in 2019. The aim of the Danish DANAMI-2 study was to evaluate thrombolytic vs invasive therapy in patients with acute myocardial infarction (MI). Between 1997 and 2001, the study enrolled a total of 1,572 patients with acute MI. Of these patients, 1,129 were enrolled at 24 referral hospitals and 443 patients at 5 invasive-treatment centres. Patients were randomised to either reperfusion with pPCI therapy at an invasive centre or fibrinolytic treatment at the admission hospital. If patients randomised to pPCI were admitted to a referral hospital, they were immediately transported to an invasive centre (transfer time...

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Posted on 10 October, 2019