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Abnormal cardiac ATP may predict SCD

Journal
JCI Insight
Abnormal heart metabolism was associated with a three-fold increased risk of life-threatening arrhythmias in adult individuals participating in a study performed by a research team of Johns Hopkins Medicine (MD, USA) [1]. Furthermore, MRI may be used to identify the high-risk individuals and predict sudden cardiac death (SCD) events. These results indicate that a metabolic approach may be helpful in the treatment or prevention of severe arrhythmias. The current approach for the prevention of SCD in high-risk individuals is an implanted cardioverter-defibrillator (ICD). However, these devices come with procedural and postprocedural risks, are costly, and, in the majority of cases, never discharge to save a life, according to first author T. Jake Samuel. There is an evident need to improve this situation, preferably through non-invasive approaches. In the current research, cardiac ATP levels of 46 patients who were scheduled to receive an ICD were ass...


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