Home > Pulmonology > Vitamin D supplement improves asthma control in adults with deficiency

Vitamin D supplement improves asthma control in adults with deficiency

Journal
Thorax
Reuters Health - 23/11/2020 - Adults with asthma who also have vitamin D deficiency may achieve better asthma control when they take 25-hydroxycholecalciferol supplements, a clinical trial suggests. The trial included 112 adults with asthma and serum 25-hydroxyvitamin-D3 levels below 30 ng/mL who were randomized to receive either oral supplements with 16,000 IU of calcifediol (25-hydroxycholecalciferol) per week or a placebo in addition to usual asthma treatment. The primary endpoint was scores on the asthma control test (ACT), which range from as low as 5 points for low control to as high as 25 points for excellent control. At baseline, mean ACT scores were 17.71 in the intervention group and 19.02 in the control group. After six months, mean ACT scores were 20.49 in the intervention group and 18.23 in the control group, a statistically significant clinical difference of 3.66 points. "The message that clinicians should take home is that patients should have ...


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