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Halting asthma medication for pregnancy tied to adverse perinatal outcomes

Reuters Health - 09/12/2020 - Pregnant women who discontinue prescribed asthma medicines may be more likely to have infants that are very premature or small for gestational age, a new study suggests. Researchers examined data on all births after 24 weeks gestation from 2000 to 2010 in Wales that had linked records on maternal prescriptions. The analysis included records on 107,573 women, including 12,690 who were prescribed at least one type of asthma medication before or during pregnancy; a total of 3,589 of these women (28.3%) received their last prescription prior to pregnancy and were considered to have discontinued treatment. Any asthma medication prescription, whether continued or discontinued during pregnancy, was associated with an increased risk of birth before 32 weeks gestation (adjusted odds ratio 1.33), small for gestational age infants below the 10th centile (aOR 1.10), and lower odds of breastfeeding (aOR 0.93). Every type of asthma medication ...


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