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Non-physicians may optimize heart failure drugs remotely

JAMA Cardiology
Reuters Health - 22/09/2020 - Remote optimization of drugs for heart failure patients with reduced ejection fraction (HFrEF) could support implementation of guideline-directed medical therapy (GDMT), researchers say. "Optimal pharmacologic treatment of patients with HFrEF is carefully scripted by evidence-based guidelines, but GDMTs are heavily underutilized in clinical practice," Dr. Akshay Desai of Brigham and Women's Hospital in Boston told Reuters Health by email. "Even when clinicians prescribe key medications such as ACE inhibitors, angiotensin receptor blockers, angiotensin-receptor neprilysin inhibitors, beta-blockers, and mineralocorticoid receptor antagonists, they frequently utilize them at lower doses than recommended for maximal treatment benefit," he said. "Data suggests that the reasons for this lack of optimal treatment are related less to patient factors or tolerability," he noted, "and more to therapeutic inertia or logistical challenges wit...

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