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Night-to-night variability in respiratory events among apnea patients

Reuters Health - 22/09/2020 - Individual patients with obstructive sleep apnea may experience considerable night-to-night variability in respiratory events, a recent meta-analysis suggests. Researchers examined data from 24 previous sleep studies that included a total of 3,250 patients with diagnosed or suspected obstructive sleep apnea. Overall, researchers didn't find a significant difference at a group level in mean Apnea-Hypopnea Index (AHI) between sequential nights in the sleep studies. However, at the individual patient level, the mean AHI difference between night one and night two of the sleep studies was -1.70/hour. "Therefore, a single night sleep study might not draw an accurate picture of the disease," said lead study author Dr. Maurice Roeder of the department of pulmonology at University Hospital Zurich in Switzerland. "The effect of longitudinal sleep monitoring on clinical outcomes like CPAP compliance and excessive daytime sleepiness a...

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