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LV volume may work as well as linear measures in pinpointing aortic regurgitation mortality risk

Journal
JAMA Cardiology
Reuters Health - 10/11/2020 - In asymptomatic patients with chronic aortic regurgitation (AR), left ventricular end-systolic volume index (LVESVi) and volume-derived LV ejection fraction (Vol-LVEF) work as well as LV end-systolic dimension index (LVESDi) and linear LVEF in pinpointing those at greatest risk of death, researchers suggest. Further, a LVESVi threshold of 45 mL/m(2) or higher was significantly associated with an increased mortality risk. "Given that transthoracic echocardiography remains the first-line modality for the comprehensive imaging assessment of AR, our findings expand the armamentarium of LV parameters available for risk stratification of asymptomatic patients," Dr. Hector Michelena of the Mayo Clinic in Rochester, Minnesota told Reuters Health by email. "In addition, our findings suggest the possibility that as a risk-marker, a LVESVi cutoff of 45 ml/m2 could be superior to its linear counterpart (LVESDI cutoff of 20 mm/m2), a notion t...


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