Home > Cardiology > Left atrial appendage occlusion tied to less afib bleeding, mortality vs DOACs

Left atrial appendage occlusion tied to less afib bleeding, mortality vs DOACs

Journal
JACC: Cardiovascular Interventions
Reuters Health -  12/01/2021 - Patients with atrial fibrillation (AF) who undergo left atrial appendage occlusion (LAAO) have similar odds of stroke as patients managed with direct-acting oral anticoagulants (DOACs) but a lower risk of major bleeding and mortality, a matched cohort study suggests. "The results suggest LAAO to be superior to DOAC in AF patients who have a predicted high risk of stroke and bleeding and adds to the evidence that LAAO is a promising stroke prevention strategy in selected AF patients," Dr. Jens Erik Nielsen-Kudsk of Aarhus University Hospital in Denmark told Reuters Health by email. As reported in JACC: Cardiovascular Interventions, Dr. Nielsen-Kudsk and colleagues compared 1,078 patients with AF who had successful LAAO with the Amplatzer Amulet device with a propensity score-matched control cohort of 1,184 incident AF patients treated with DOACs. The mean age was 75 in both groups and about 62% were men. Propensity score matching...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on