Left atrial appendage occlusion tied to less afib bleeding, mortality vs DOACs

Reuters Health -  12/01/2021 - Patients with atrial fibrillation (AF) who undergo left atrial appendage occlusion (LAAO) have similar odds of stroke as patients managed with direct-acting oral anticoagulants (DOACs) but a lower risk of major bleeding and mortality, a matched cohort study suggests. "The results suggest LAAO to be superior to DOAC in AF patients who have a predicted high risk of stroke and bleeding and adds to the evidence that LAAO is a promising stroke prevention strategy in selected AF patients," Dr. Jens Erik Nielsen-Kudsk of Aarhus University Hospital in Denmark told Reuters Health by email. As reported in JACC: Cardiovascular Interventions, Dr. Nielsen-Kudsk and colleagues compared 1,078 patients with AF who had successful LAAO with the Amplatzer Amulet device with a propensity score-matched control cohort of 1,184 incident AF patients treated with DOACs. The mean age was 75 in both groups and about 62% were men. Propensity score matching...

Please login to read the full text of the article.

If you have no account yet, please register now.

Posted on 12 January, 202119 January, 2021