Thank you for choosing our Medicom Conference Report of the 2021 American Heart Association Scientific Sessions. This yearâs meeting was rich in innovative science, late-breaking studies, and engaging virtual content.
In the following pages, you will find late-breaking science on digital interventions in atrial fibrillation, remote virtual programs for population management of hypertension and hyperlipidemia, exciting data on novel anticoagulants and new evidence in heart failure, vascular disease and coronary disease.
We hope you find our peer-reviewed summaries informative, engaging and balanced. Most of all, we wish you all a safe and healthy 2022 and hope that this year brings our scientific community even closer together.
Sincerely,
Marc Bonaca
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Biography
Marc P. Bonaca, MD, MPH, is a Cardiologist and Vascular Medicine Specialist who serves as the Executive Director of CPC Clinical Research and CPC Community Health at the University of Colorado Anschutz Medical Campus. He is the Director of Vascular Research and an Associate Professor of Medicine at the University of Colorado School of Medicine and the inaugural holder of the William R. Hiatt Endowed Chair in Cardiovascular Research.
Dr Bonaca earned his medical degree from the University of Connecticut School of Medicine and his Masters in Public Health at Harvard University. He served as a Medical House Officer at Brigham and Womenâs Hospital and Harvard Medical School. After completion of his training, he joined the faculty of the Cardiovascular Division and Vascular Medicine section of Brigham and Womenâs Hospital and Harvard Medical School and became an Investigator at the TIMI Study Group.
Dr Bonacaâs research focus is on ischemic risk in patients with atherosclerotic vascular disease, risk prediction, and risk modification through the use of pharmacologic and biologic therapies. His key areas of interest include patients with peripheral artery disease, polyvascular disease and diabetes with a focus on the breadth of risk including ischemic limb outcomes, microvascular complications and major adverse cardiovascular events.
Conflict of Interest Statement:
Grant support to BWH from AstraZeneca, MedImmune, Merck, PfizerGrant support to CPC from Amgen, AstraZeneca, Bayer, Janssen, NovoNordisk, Sanofi
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Table of Contents: AHA 2021
Featured articles
The scope of remote healthcare in hypertension and hyperlipidaemia
Atrial Fibrillation
Updates on anti-arrhythmic agents
New developments in remote diagnostics and monitoring of AF
Head-to-head: Efficacy of dabigatran versus warfarin on cognitive impairment
Posterior left pericardiotomy safe and effective in reducing atrial fibrillation
LAA ligation did not reduce recurrent atrial arrhythmias in persistent AF
Equal benefits of early rhythm control in AF subtypes
CVD Risk Reduction
Remote healthcare programme improves hypertension and lipid control
Novel oral PCSK9 inhibitor shows promising results for hypercholesterolaemia
REVERSE-IT: Interim analysis shows promising effect of bentracimab on ticagrelor reversal
No significant effect of aspirin on reducing cognitive impairment
Milvexian phase 2 data supports safety and efficacy for VTE prevention after total knee replacement
Network meta-analysis observes no clear effect of eicosapentaenoic acid on CV outcomes
Heart Failure
Empagliflozin efficacious in HF patients with preserved ejection fractions â„50%
EMPULSE: Empagliflozin improves outcomes of acute heart failure
CHIEF-HF: Canagliflozin improves health status in heart failure
DREAM-HF: MPC therapy for HFrEF did not meet primary endpoint
Therapeutic approaches in heart failure with diabetes
Acute Coronary Syndrome
Ticagrelor cessation: early CABG non-inferior to delayed surgery
Distinguishing patients before AMI based on plaque morphology
Vascular Diseases: PVD
Rivaroxaban regimen beneficial after revascularisation for claudication
LIBERTY 360 shows quality-of-life improvements after peripheral vascular intervention
Deficient treatment outcomes after PVI in Black and low-income adults with PAD
REDUCE-IT: Cardiovascular risk reduction with icosapent ethyl in PAD
Vascular Diseases: CAD
Long-term reduced risk of CV events with ticagrelor plus aspirin after CABG
Early surgery outperforms conservative management in asymptomatic severe aortic stenosis
External support device for SVG grafts in CABG surgery shows promise
COVID-19 & the Heart
Blood pressure control disrupted during the pandemic
Icosapent ethyl did not reduce the risk of hospitalisation in COVID-19
Neutral effect of P2Y12 inhibitors in non-critical COVID-19 hospitalisations
COVID-19 mRNA vaccination benefits outweigh the risk for myocarditis
Other
2021 Guideline for Chest Pain: Top 10 takeaways
Accurate ejection fraction assessment in paediatric patients via artificial intelligence
Concomitant tricuspid annuloplasty reduces treatment failure in moderate tricuspid regurgitation
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New developments in remote diagnostics and monitoring of AF
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