Home > Cardiology > Early use ICD after PCI shows beneficial effect on survival in patients at high risk of death after STEMI

Early use ICD after PCI shows beneficial effect on survival in patients at high risk of death after STEMI

Conference
ESC 2019
Trial
DAPA
Patients who are at high-risk of death may benefit from early implantable cardioverter-defibrillator (ICD) implantation after they have had primary percutaneous coronary intervention (PCI). Although the trial was halted prematurely due to a slow accrual rate, the early data warrant further research into this particular field. The DAPA trial aimed to examine whether ICD implantation between 30 and 60 days after primary angioplasty for STEMI was able to offer a survival benefit in patients who are at high risk of death, which was defined as at least one of the following: primary ventricular fibrillation, left ventricular ejection fraction below 30%, Killip class 2 or higher, or thrombolysis in myocardial infarction flow less than 3 after primary PCI. Patients were randomised to prophylactic ICD implantation or optimal medical therapy. Primary endpoint of the study was all-cause mortality after at least 3 years of follow-up for each patient. The secondary end...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on