Home > Urology > Mirabegron likely best option for resistant overactive bladder in men

Mirabegron likely best option for resistant overactive bladder in men

Journal
European Urology
Reuters Health - 03/02/2021 - For men with overactive bladder (OAB) who fail antimuscarinics, mirabegron 50 mg is an option supported by the highest level of evidence, a systematic review reveals. "OAB has the same prevalence in men as in women," Dr. Cosimo De Nunzio of Sapienza University of Rome, Italy told Reuters Health by email. "However, men are rarely investigated in clinical trials evaluating new treatment modalities and are undertreated in clinical practice." Although antimuscarinics are the first-line option, he said, patients taking the drugs frequently stopped treatment (53%) or switched to another antimuscarinic (22%). "Switching and discontinuation rates vary according to different antimuscarinics," he noted. "These data suggest that many men discontinued treatment for unknown reasons. In some countries, as in Italy, OAB drugs are not reimbursed, and it is a limitation and could explain the low drug compliance observed in clinical practice."...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on