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Delaying radiation likely preferable after localized prostate cancer resection

Journal
The Lancet
Reuters Health - 05/10/2020 - Men with localized prostate cancer can likely avoid adjuvant radiation following surgery and receive the treatment if cancer recurs or relapses, according to a systematic review and meta-analysis published in The Lancet. "Older clinical trials had shown that for men with localized prostate cancer, immediate radiotherapy (after surgery) reduced the risk of cancer coming back. But they had not conclusively shown that it improved longer term outcomes; in addition, we now have more sensitive tests that can pick up the return of cancer earlier," coauthor Dr. Clare Vale of University College Hospital, London, UK, told Reuters Health by email. "This meant up until now, clinicians were uncertain whether giving radiotherapy immediately following surgery offered patients better outcomes than delaying radiotherapy until there was an indication of the cancer progressing," she said. In the past week, three teams have reported on randomized tr...


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