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Image-guided biopsy may help some avoid breast-cancer surgery

JAMA Surgery
Reuters Health - 19/10/2020 - Following neoadjuvant chemotherapy, image-guided vacuum-assisted biopsy (VAB) can reliably identify a subgroup of patients with no residual disease in the breast, according to an analysis of pooled data drawn from three continents. "Our findings support the use of a standardized assessment protocol using VAB in carefully selected patients to assess if there is residual cancer left in the breast after neoadjuvant chemotherapy," Dr. Marios Konstantinos Tasoulis of The Royal Marsden NHS Foundation Trust in London told Reuters Health by email. "These results could inform the design of clinical trials testing the safety of omission of surgery in exceptional responders." In a paper in JAMA Surgery, Dr. Tasoulis and colleagues note that with improvements in treatment, especially routine use of adjuvant radiotherapy and systemic therapy, certain patients may not benefit from surgery. To investigate further, the researchers examined data ...

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