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Even mild NAFLD associated with higher mortality

Journal
Gut
Reuters Health - 20/11/2020 - All stages of nonalcoholic fatty liver disease (NAFLD) are associated with significantly increased overall mortality, and this risk increases progressively with worsening disease, Swedish researchers have found. Deaths from extrahepatic cancer and cirrhosis accounted for most of this excess mortality, they report in Gut. "Our findings underscore the importance of reversing all stages of NAFLD, while also highlighting the need for effective public health strategies designed to prevent cancer and cirrhosis, in this high-risk and growing population," Dr. Jonas F. Ludvigsson of Karolinska Institutet, in Stockholm, and colleagues write. NAFLD is the most common cause of chronic liver disease in the Western world and affects almost 25% of U.S. and European adults, the researchers note. Nearly a third of these patients go on to develop progressive/non-fibrotic steatohepatitis and fibrosis, which can lead to cirrhosis, decompensated live...


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