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Transcatheter valve replacement curbs tricuspid regurgitation in many

JACC: Cardiovascular Interventions
Reuters Health - 26/11/2020 - Patients at high surgical risk with severe, symptomatic functional tricuspid regurgitation (TR) treated with a first-generation transcatheter tricuspid-valve implantation (TTVI) system show significant clinical improvement, according to a multicenter report of compassionate use. "Further refinement of the implantation algorithm may reduce malpositioning of the device, leading to better TR reduction," Dr. Rebecca T. Hahn of New York-Presbyterian Hospital, in New York City, told Reuters Health by email. "Device iteration towards reduced invasiveness and improved patient-selection criteria are needed to improve procedural safety, along with larger prospective studies to assess the impact on long-term clinical outcomes." Isolated TR surgery is associated with high in-hospital mortality, Dr. Hahn and her colleagues note in JACC: Cardiovascular Interventions. To evaluate the feasibility and safety of TTVI in patients at "extreme" surgical ris...

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