Obesity independently tied to longer survival after cardiac resynchronization

Reuters Health - 09/11/2020 - Obesity is associated with longer survival after cardiac resynchronization therapy (CRT) regardless of improvements in left ventricular ejection fraction (LVEF), according to a new study. Previous studies have found an association between lower BMI and increased mortality among patients receiving CRT, but the reasons behind this link are not clear. Dr. John W. Rikard and colleagues of the Cleveland Clinic Foundation, in Ohio, evaluated whether the survival advantage associated with obesity was related to left ventricular remodeling and improved LVEF in their study of 206 patients with normal BMI, 297 overweight patients (BMI, 25 to <35 kg/m2), and 301 obese patients (BMI, 35 kg/m2 or higher). The mean increase in LVEF following CRT implantation did not differ significantly among normal-weight patients (8.1%), overweight patients (8.8%) and obese patients (9.3%). Although CRT response, defined as an improvement of at lea...

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Posted on 9 November, 202020 November, 2020