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PURE study: risk factors cardiovascular disease in low- and high-income countries

Expert
Dr Salim Yusuf
Conference
ESC 2019
Trial
PURE
Approximately 70% of the risk of cardiovascular disease (CVD) and death can be explained by modifiable risk factors [1]. Globally, the largest contributing risk factor for CVD are metabolic risk factors (41.2%) of which hypertension (22%) was the leading risk factor in that category. Yet, a large variation was observed between countries with different levels of income with regard to the relative impact of the CVD risk factors. The PURE study assessed data from 21 countries spreading 5 continents, and aimed to describe the incidence of various diseases and related deaths in countries at different economic levels (high-, middle- and low-income) and to document the relative importance of risk factors for CVD and mortality overall and in these countries. A total number of 152,722 subjects without CVD from high-, middle- and low-income countries were included. Fourteen risk factors were assessed, consisting of behavioural risk factors (i.e. tobacco use, diet, a...


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