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Complete revascularisation superior to culprit-lesion-only PCI

Conference
ESC 2019
Trial
COMPLETE
Patients with STEMI and multivessel coronary artery disease achieve more benefit from complete revascularisation than from culprit-lesion-only PCI with regard to reducing the risk of CV death or MI. The COMPLETE trial randomised 4,041 patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI) and had non-culprit multivessel coronary disease (defined as a 70% stenosis or 50-69% stenosis with fractional flow reserve ≤0.8). Exclusion criteria were planned revascularisation of non-culprit lesion, planned surgical revascularisation, non-cardiovascular co-morbidity reducing life expectancy to <5 years, prior coronary artery bypass graft (CABG) surgery, and any factor precluding 5-year follow-up. Mean patient age was 62 years, 19% was female, 19% of patients had diabetes, and follow-up was 3 years. Primary endpoint was cardiovascular death or myocardial infarction; this occurred in 7.8% of th...


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