ASCO 2024

Gastrointestinal: Colorectal Cancer

No survival benefit of tumour debulking for patients with multi-organ metastatic CRC

Presented By

Dr Elske Gootjes, Radboudumc, the Netherlands

Trial

Phase 3, ORCHESTRA

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:53

Thermal ablation of small-size colorectal liver metastases is non-inferior to resection

Presented By

Prof. Martijn Meijerink, Amsterdam UMC, the Netherlands

Trial

Phase 3, COLLISION

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:48

Benefit of first-line nivolumab/ipilimumab in MSI-H/dMMR metastatic CRC

Presented By

Prof. Heinz-Josef Lenz, University of Southern California Norris Comprehensive Cancer Center, CA, USA

Trial

Phase 3, CheckMate 8HW

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:44

Neoadjuvant checkpoint blockade in MSI-H/dMMR CRC

Trial

Phase 1/2, NICHE-2, NEOPRISM-CRC

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:36

CodeBreaK 300: Promising survival trends in KRAS G12C-mutated mCRC

Presented By

Prof. Marwan Fakih, City of Hope Comprehensive Cancer Center, CA, USA

Trial

Phase 3, CodeBreaK 300

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:26

Gastrointestinal: Upper GI Cancer

FLOT outperforms CROSS in resectable oesophageal cancer

Presented By

Prof. Jens Höppner, University of Bielefeld, Germany

Trial

Phase 3, ESOPEC

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:14

Nivolumab/ipilimumab combination outperforms TKIs in unresectable HCC

Presented By

Dr Peter Galle, Universitätsmedizin Mainz, Germany

Trial

Phase 3, CheckMate 9DW

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:10

No advantage of neoadjuvant radiochemotherapy over neoadjuvant chemotherapy in borderline resectable pancreatic cancer

Presented By

Dr Masafumi Ikeda, National Cancer Center Hospital East, Japan

Trial

Phase 3, GABARNANCE

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 15:06

Breast Cancer

Lung Cancer

Osimertinib significantly improves PFS in patients with unresectable stage III EGFR-mutated NSCLC

Presented By

Prof. Suresh Ramalingam, Emory School of Medicine, GA, USA

Trial

Phase 3, LAURA

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:30

First-line lorlatinib provides unprecedented improvement for patients with advanced ALK-positive NSCLC

Presented By

Prof. Benjamin Solomon, Peter MacCallum Cancer Centre, Australia

Trial

Phase 3, CROWN

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:28

Comparable benefit of video- and in-person-delivered palliative care

Presented By

Dr Joseph Greer, Harvard Medical School, MA, USA

Trial

REACH PC

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:25

Consolidation with durvalumab improves survival in LS-SCLC

Presented By

Dr David Spigel, Sarah Cannon Research Institute, TN, USA

Trial

Phase 3, ADRIATIC

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:23

Subcutaneous amivantamab non-inferior and more convenient than intravenous amivantamab

Presented By

Dr Natasha Leighl, Princess Margaret Cancer Centre, Canada

Trial

Phase 3, PALOMA-3

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:19

Melanoma

Highly significant event-free survival benefit with neoadjuvant nivolumab/ipilimumab in stage III melanoma

Presented By

Prof. Christian Blank, Antoni van Leeuwenhoek, the Netherlands

Trial

Phase 3, NADINA

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:16

Neoadjuvant intralesional daromun improves relapse-free survival in stage III melanoma

Presented By

Prof. Axel Hauschild, Universitätsklinikum Schleswig-Holstein, Germany

Trial

Phase 3, PIVOTAL

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:13

Intratumoural tilsotolimod shows no benefit for advanced refractory melanoma

Presented By

Prof. Caroline Robert, Gustave Roussy, France

Trial

Phase 3, ILLUMINATE-301

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:09

Genitourinary Cancer

Immune-enhancing nutrition does not affect complication rate of radical cystectomy

Presented By

Prof. Jill Hamilton-Reeves, University of Kansas Medical Center, KS, USA

Trial

Phase 3, SWOG S1600

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:05

Biomarkers for treatment of renal cell carcinoma

Trial

Phase 3, CLEAR, KEYNOTE-426, IMmotion010

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 14:00

ctDNA changes as biomarker for pembrolizumab response in advanced urothelial carcinoma

Presented By

Prof. Thomas Powles, Barts Cancer Institute, UK

Trial

Phase 3, KEYNOTE-361

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:51

Highest efficacy of nivolumab/chemotherapy in lymph-node-only metastatic urothelial carcinoma

Presented By

Prof. Matthew Galsky, Tisch Cancer Institute, NY, USA

Trial

Phase 3, CheckMate 901

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:48

Genitourinary: Prostate Cancer

Metformin does not prevent progression of low-risk prostate cancer

Presented By

Dr Anthony Joshua, Princess Margaret Cancer Centre, Canada

Trial

Phase 3, MAST

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:46

Baseline ctDNA has both prognostic and predictive value in mCRPC

Presented By

Prof. Johann de Bono, Royal Marsden Hospital, UK

Trial

Phase 3, PSMAfore

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:44

Oxybutynin significantly decreases frequency and severity of hot flashes in men on ADT

Presented By

Dr Brad Stish, Mayo Clinic, MN, USA

Trial

Phase 2, Alliance 222001

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:41

Gynaecological Cancer

Batiraxcept shows promise in high AXL-expressing, platinum-resistant ovarian cancer

Presented By

Dr Katherine Fuh, University of California San Francisco, CA, USA

Trial

Phase 3, AXLerate-OC

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:38

No lymphadenectomy for advanced ovarian cancer without suspicious nodes

Presented By

Prof. Jean-Marc Classe, Nantes Université, France

Trial

Phase 3, CARACO

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:34

SIENDO: Efficacy benefit of selinexor in TP53 wildtype endometrial cancer

Presented By

Dr Vicky Makker, Memorial Sloan Kettering Cancer Center, NY, USA

Trial

Phase 3, SIENDO

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:32

Novel regimen for HR-positive endometrial cancer on the way?

Presented By

Dr Angela Green, Memorial Sloan Kettering Cancer Center, NY, USA

Trial

Phase 2

Conference

ASCO 2024

Type

Peer-reviewed article

18 July 2024 13:30