Home
>
Warning: Undefined property: WP_Error::$name in /var/www/medicalconferences/wp-content/themes/writers-blogily-new/category.php on line 78
Deprecated: strtolower(): Passing null to parameter #1 ($string) of type string is deprecated in /var/www/medicalconferences/wp-content/themes/writers-blogily-new/category.php on line 78
Warning: Undefined property: WP_Error::$name in /var/www/medicalconferences/wp-content/themes/writers-blogily-new/category.php on line 84
> Medical Specialty
Warning: Undefined property: WP_Error::$name in /var/www/medicalconferences/wp-content/themes/writers-blogily-new/category.php on line 78
Deprecated: strtolower(): Passing null to parameter #1 ($string) of type string is deprecated in /var/www/medicalconferences/wp-content/themes/writers-blogily-new/category.php on line 78
Warning: Undefined property: WP_Error::$name in /var/www/medicalconferences/wp-content/themes/writers-blogily-new/category.php on line 84
> Medical Specialty
Medical Specialty
Featured articles
Nearly all participants respond to deucravacitinib in lichen planopilaris study
New horizon for classifying and managing vascular anomalies
CONTENTS
Online First
How to recognise and manage Schnitzler syndrome in clinical practice
Expanding treatment armamentarium for actinic keratosis and Bowen’s disease
VEXAS syndrome and its cutaneous manifestations
Management of atopic dermatitis in children in 2025
New horizon for classifying and managing vascular anomalies
How to deal with misinformation in the medical world
Symptomatic embolisms after AF ablation: new insights on outcomes and predictors
Atrial fibrillation screening: beneficial in high-risk patients
Need for post-TAVI pacemaker implantation linked to poorer patient outcomes
Rivaroxaban is a viable alternative to warfarin in post-MI left ventricular thrombus
Can we manage INOCA in women with intensive medical therapy?
STRIDE: Semaglutide fruitful for patients with type 2 diabetes and PAD
Pulsed field non-inferior to cryoballoon ablation in symptomatic paroxysmal AF
SmartfIRE shows lasting relief and improved quality of life 1-year post-ablation
Activity analysis: A predictor for arrhythmias and clinical deterioration?
SMART-CHOICE 3: Clopidogrel preferred over aspirin in high-risk patients after PCI
FAIR-HF2: the value of intravenous iron in patients with HF plus iron deficiency
Restricting fluid in HF may not be good practice after all
TRILUMINATE: Clear benefit of TEER procedure with TriClip device in severe TR
Myocardial fibrosis triples arrhythmia risk in NICM patients
Analysis of the MORE-CRT MPP trial shows: Marked clinical benefit by MPP in echo non-responders
S-ICD: an alternative for sudden cardiac death prevention in Brugada Syndrome
REVERSE-IT: Bentracimab restores platelet function in ticagrelor-users
Oral semaglutide yields excellent CV outcomes in high-risk type 2 diabetes
HOST-BR: Searching for the optimal duration of DAPT after PCI
Lorundrostat represents novel class of BP-lowering drugs
General
Interview: Medicare’s first drug price negotiations: concerning?
Talking Medicine in 2024
Top 10 medical breakthroughs in 2023
Why Medicom Medical Publishers champions peer review
Heroes of Medicine
Addressing health risks of loneliness and social isolation
Understanding the stresses and strains of being a doctor
Top 14 Medical Innovations for 2022
Cardiology
ACC 2025 Highlights Podcast
Symptomatic embolisms after AF ablation: new insights on outcomes and predictors
Atrial fibrillation screening: beneficial in high-risk patients
Need for post-TAVI pacemaker implantation linked to poorer patient outcomes
Rivaroxaban is a viable alternative to warfarin in post-MI left ventricular thrombus
Can we manage INOCA in women with intensive medical therapy?
STRIDE: Semaglutide fruitful for patients with type 2 diabetes and PAD
Pulsed field non-inferior to cryoballoon ablation in symptomatic paroxysmal AF
SmartfIRE shows lasting relief and improved quality of life 1-year post-ablation
Activity analysis: A predictor for arrhythmias and clinical deterioration?
SMART-CHOICE 3: Clopidogrel preferred over aspirin in high-risk patients after PCI
FAIR-HF2: the value of intravenous iron in patients with HF plus iron deficiency
Restricting fluid in HF may not be good practice after all
TRILUMINATE: Clear benefit of TEER procedure with TriClip device in severe TR
Myocardial fibrosis triples arrhythmia risk in NICM patients
Analysis of the MORE-CRT MPP trial shows: Marked clinical benefit by MPP in echo non-responders
Myocardial fibrosis triples arrhythmia risk in NICM patients
S-ICD: an alternative for sudden cardiac death prevention in Brugada Syndrome
REVERSE-IT: Bentracimab restores platelet function in ticagrelor-users
Oral semaglutide yields excellent CV outcomes in high-risk type 2 diabetes
HOST-BR: Searching for the optimal duration of DAPT after PCI
Lorundrostat represents novel class of BP-lowering drugs
Letter from the Editor AHA 2024
PROMPT-AF: Novel ablation strategy improves outcomes for persistent AF
ARREST-AF: The true impact of risk factor management on AF recurrence after ablation
VANISH2: Antiarrhythmic drug therapy or catheter ablation in prior myocardial infarction complicated by ventricular tachycardia?
OPTION: LAAC over OAC after ablation in patients with AF and increased stroke risk
Head-to-head: Cryoballoon vs radiofrequency ablation in persistent AF
Will myeloperoxidase inhibition benefit patients with heart failure?
Is intranasal bumetanide a viable diuretic option in congestive HF?
REALIZE-K: MRA treatment optimisation in HFrEF plus hyperkalaemia
SUMMIT: Tirzepatide reduces cardiovascular events in HFpEF plus obesity
CLEAR Outcomes: Bempedoic acid reduces MACE and MALE in patients with PAD
GLORIOUS: Restrictive versus liberal oxygenation during CPB-assisted surgery
GLORIOUS: GLP-1 agonist did not meet primary endpoint in CABG
CLEAR SYNERGY: Can routine spironolactone improve post-MI outcomes?
ENBALV: Edoxaban or warfarin as anticoagulant after bioprosthetic valve replacement?
ZODIAC: Can we improve lipid-lowering strategies in ACS?
KRAKEN: Encouraging phase 2 results of Lp(a)-lowering muvalaplin
Reconditioned pacemakers may save lives in low/middle-income countries
Comparing dual antihypertensive combination therapies in a South Asian population
BPROAD: Intensive or standard BP treatment strategy in type 2 diabetes?
Promising results for CRISPR-based therapy in ATTR-CM
NUDGE-FLU: Effect of science-informed letters on influenza vaccination rates
Novel small-interfering RNA effectively reduced Lp(a) in phase 2
Full-dose or reduced-dose DOACs in high-risk VTE on extended therapy?
AHA Names 7 Cardiovascular Research Breakthroughs in 2024
Guidelines for the management of elevated blood pressure and hypertension
Guidelines for the management of chronic coronary syndromes
Guidelines for the management of atrial fibrillation
Guidelines for the management of peripheral artery and aortic diseases
EPIC-CAD: What is the best antithrombotic approach in high-risk AF plus stable CAD?
OCEANIC-AF: Asundexian inferior to apixaban for ischaemic stroke prevention in AF
MIRACLE-AF: Elegant solution to improve AF care in rural China
SUPPRESS-AF: What is the value of adding LVA ablation to PVI in AF?
ABYSS: Can beta-blocker safely be interrupted post-MI?
SWEDEGRAFT: Can a no-touch vein harvesting technique improve outcomes in CABG?
Bioadaptor meets expectations in reducing target lesion failures in coronary artery disease
REC-CAGEFREE I: Can we avoid permanent stenting with drug-coated balloons?
OCCUPI: OCT-guided PCI improves outcomes in complex CAD
Low-dose 3-drug pill GMRx2 shows promise in lowering BP
Is administering BP medication in the evening better than in the morning?
VERONICA: Improving BP control in Africa with a simple strategy
FINEARTS-HF: Finerenone improves outcomes in heart failure with preserved ejection fraction
MRAs show varied efficacy in heart failure across ejection fractions
MATTERHORN: Transcatheter repair matches surgery for HF with secondary mitral regurgitation
RESHAPE-HF2: Not a “tie-breaker” for TEER in heart failure
STEEER-AF: Shockingly low adherence to ESC atrial fibrillation guidelines
SCOFF: To fast or not to fast, that’s the question
WESTCOR-POC: Point-of-care hs-troponin testing increases emergency department efficiency
PROTEUS: Can AI improve decision-making around stress echocardiography?
RAPIDxAI: Can AI-augmented chest pain assessment improve cardiovascular outcomes?
HELIOS-B: Vutrisiran candidate for SoC in ATTR cardiomyopathy
Does RAS inhibitor discontinuation affect outcomes after non-cardiac surgery?
Novel approach to managing severe tricuspid regurgitation proves its value
NOTION-3: TAVI plus PCI improves outcomes in CAD plus severe aortic stenosis
RHEIA: TAVI outperformed surgery in women with aortic stenosis
Meet the Expert: Dr Abdullahi Mohamed on Iron Deficiency in Patients with HF
High risk for recurrent vascular events in young stroke patients
Anticoagulation or antiplatelet as secondary prevention for cancer-related strokes?
Effects of semaglutide on MACE irrespective of HF status
SEQUOIA-HCM: Aficamten demonstrates clinical efficacy in obstructive HCM
ARIES-HM3 trial: Subgroup analysis in patients with prior need for aspirin
Three diuretic regimens compared in the DEA-HF study
Adding a mineralocorticoid receptor modulator in heart failure with CKD
Empagliflozin did not reduce mortality for HF after MI regardless of T2D status
SGLT2 inhibitors decrease atrial fibrillation risk in patients with HFrEF
SGLT2 inhibition: Major and early impact on heart failure hospitalisation risk
Individualised diuretic titration in acute HF without a physician
Intravenous iron deficiency treatment improves exercise capacity in patients with HFpEF
CD34+ stem cells promote reverse cardiac remodelling after acute MI
Sex-specific outcomes and resource utilisation after HF hospitalisation
Application of guideline-directed medical therapy in patients with HFrEF in the Netherlands
PAP-guided management system appears safe in patients with HF
Delivery of CRT guided by non-invasive anatomy assessment
RELIEVE-ing HFrEF with interatrial shunting
Algorithm-based remote patient monitoring was associated with lower mortality in a retrospective cohort study
High mortality and morbidity in suspected de novo HF in outpatient care
Bio-ADM as a marker for congestion in patients hospitalised for acute HF
Hypertonic saline not effective in ambulatory patients with heart failure?
No effect of low-dose carperitide on mortality or hospitalisation in acute HF
Meet the Trialist: Innovating cardiac monitoring with MONITOR-HF
Preventive PCI of vulnerable intracoronary plaque leads to favourable outcomes
KARDIA-2: Add-on zilebesiran effectively lowers blood pressure
BRIDGE-TIMI 73a: Olezarsen halves triglyceride levels
Plozasiran: A novel approach to severe hypertriglyceridaemia
High-risk and very high-risk patients meet LDL-cholesterol targets with lerodalcibep
No cardioprotective effect of ACE inhibitors in patients with cancer
SGLT2 inhibition in heart failure more advantageous for women than men
Anxiety and depression: Lifestyle influential in MACE prevention
Self-expanding versus balloon-expendable TAVR in patients with small aortic annuli
Safety of TAVI non-inferior to SAVR for patients with lower surgical risk
Interatrial shunt for HF: neutral primary endpoint but potential benefit in HFrEF
Peripheral artery disease: procedure-guidance by IVUS superior to angiography
IVUS-guided PCI beats angiography in patients with acute coronary syndrome
Addressing frailty in patients undergoing TAVR
ACS: Necessary DAPT after PCI may be shorter than currently advised
AEGIS-II: ApoA-1 did not reduce MACE in patients with myocardial infarction but may provide benefit in patients with high LDL levels
REDUCE-AMI: Re-evaluating the role of routine beta-blockade in patients with acute myocardial infarction
STEP-HFpEF DM: Semaglutide beneficial in patients with HFpEF and diabetes
IMPROVE-HCM: Promising results for ninerafaxstat in non-obstructive HCM
Meet the Trialist: The “Sweet Spot” from RELIEVE-HF
Meet the Trialist: The EMPACT-MI trial findings
Ablate-by-LAW: CT-determined left atrial wall thickness for ablation titration in atrial fibrillation
Personalised LAWT-guided ablation non-inferior to CLOSE protocol for paroxysmal atrial fibrillation
Style-AF: Improved outcomes with vascular closure versus figure-of-eight suture
Advantage of PREVENTIVE ablation plus implantable cardioverter-defibrillator in ischaemic cardiomyopathy
ASTRO AF: No benefit of staged left atrial appendage isolation cryoballoon ablation over radiofrequency ablation
Pulsed-field ablation vs high-power short-duration radiofrequency in paroxysmal AF
CryoCure-VT: Endocardial ultra-low temperature cryoablation effective in sustained monomorphic ventricular tachycardia
PIRECNA: Cardioneuroablation is feasible for vagally-induced atrioventricular block
MRI head-to-head comparison of lesion quality following various ablation techniques
“Single-shot” conformable catheter shows promising efficacy in paroxysmal atrial fibrillation
AF burden versus classical AF classification in predicting arrhythmia recurrence
ARTESiA: Stroke risk unaffected by subclinical atrial fibrillation duration
Ablation strategy and the number of repeat procedures not associated with atrial fibrillation recurrence
Factors associated with negative outcomes in post-operative atrial fibrillation
Smartphone rhythm monitoring optimises AF management following cardiac surgery
SMART-AV and SMART-CRT: Improved cardiac outcomes with algorithm-adapted atrioventricular delay
Premature battery depletion can affect a quarter of subcutaneous cardioverter defibrillators
New atrial fibrillation associated with a high risk of major cardiovascular outcomes
Matters of the heart: late-breaking news from the American College of Cardiology
Successful results for semaglutide in the highly anticipated SELECT trial
Can a walking intervention improve functional status and quality of life in HFrEF?
Head-to-head: Surgical embolectomy versus ultrasound-assisted thrombolysis in high-risk pulmonary embolism
Abelacimab substantially lowers bleeding risk compared with rivaroxaban
Liraglutide may improve post-ablation outcomes in obese patients with AF
Single or dual cardioversion in patients with obesity and AF?
NOAH-AFNET 6: Does the duration of AHRE influence response to edoxaban?
ARTESIA: How useful is anticoagulation in subclinical AF?
Jewel IDE: High compliance rates for novel patch wearable cardioverter defibrillator
Sudden cardiac death in athletes: incidence, causes, and trends over 20 years
Encouraging data for lepodisiran as Lp(a) lowering therapy
Gene editing may change the treatment landscape of hypercholesterolaemia
REPRIEVE: Mechanisms behind MACE reduction in HIV population on pitavastatin
Recaticimab may offer a solution for uncontrolled hypercholesterolaemia
Edoxaban versus warfarin in chronic thromboembolic pulmonary hypertension
Sodium intake and blood pressure: new insights
Intensive BP intervention reduces risk of dementia
Post-partum intervention lowers BP after hypertensive pregnancy
Biannual zilebesiran associated with substantial BP reductions
MINT: Liberal or restrictive transfusion strategy in MI with anaemia?
ORBITA-2 confirms PCI effective for symptom relief in patients with stable angina
Nicotinamide riboside shows promising trend for walking function in PAD
Pemafibrate reduces microvascular complications of PAD and T2D
Dapagliflozin improves cardiometabolic outcomes in myocardial infarction
Interview: Medicare’s first drug price negotiations: concerning?
Top 10 medical breakthroughs in 2023
Traditional Chinese medicine successful in HFrEF
CRT upgrade benefits patients with HFrEF and an ICD
Catheter ablation saves lives in end-stage HF with AF
Immediate or staged revascularisation in STEMI plus multivessel disease?
Lp(a) and cardiovascular events: which test is the best?
Meta-analysis: Does FCM improve clinical outcomes in HF?
No benefit of extracorporeal life support in MI plus cardiogenic shock
HEART-FID: Is intravenous ferric carboxymaltose helpful in HFrEF with iron deficiency?
Heart failure: the 2023 update
Should we use anticoagulation in AHRE to prevent stroke?
Functional revascularisation outperforms culprit-only strategy in older MI patients
Minimising atrial pacing does not reduce the risk for AF in sinus node disease
Results of FRAIL-AF trial suggest increased bleeding risk with DOACs
Natriuresis-guided diuretic therapy to facilitate decongestion in acute HF
Guidelines for Acute Coronary Syndrome
ARAMIS: Can anakinra alleviate acute myocarditis?
Can aspirin be omitted after PCI in patients with high bleeding risk?
Guidelines for the management of cardiomyopathies
DICTATE-AHF: Early dapagliflozin to manage acute HF
The optimal duration of anticoagulation therapy in cancer patients with DVT
Expedited transfer to a specialised centre does not improve cardiac arrest outcomes
Angiography vs OCT vs IVUS guidance for PCI: a network meta-analysis
Cardiovascular disease and diabetes: new guidelines
Does colchicine prevent perioperative AF and MINS?
DAPT or clopidogrel monotherapy after stenting in high-risk East-Asian patients?
OCTOBER trial: OCT-guided PCI improves clinical outcomes in bifurcation lesions
Acoramidis improves survival and functional status in ATTR-CM
STEP-HFpEF: Semaglutide safe and efficacious in HFpEF plus obesity
Inorganic nitrate strongly reduces CIN in high-risk patients undergoing angiography
Diagnostic tool doubles cardiovascular diagnoses in patients with COPD or diabetes
Guidelines for the management of endocarditis
How to manage arterial thrombosis and thromboembolism in COVID-19?
Frequent co-existence of atrial fibrillation and obstructive sleep apnoea in stroke patients
Protein-bound uremic toxins predict HF events and death in patients with CKD
VOICE-COVID-II : Alexa successful in SARS-CoV-2 symptoms screening
HF patients with metabolic dysfunction at high risk to develop depressive symptoms
Standardised diuretic protocol significantly increases natriuresis in acute HF
Low concentrations of VEGF-C: a negative prognostic factor
Patisiran benefits maintained over 18 months in patients with transthyretin amyloidosis
Aficamten may lower symptom burden in non-obstructive hypertrophic cardiomyopathy
Sacubitril/valsartan reduces natriuretic peptides in HF patients with ejection fraction >40%
Clinically relevant reduction in HF hospitalisation due to haemodynamic monitoring
TRACER-HF: Trientine reduced biomarkers up to 8 weeks
Dapagliflozin improves LAVI, LV mass, and concentration of natriuretic peptides after 6 months
NUDGE-FLU: Repeated electronic nudges improve flu vaccination rates in patients with HF
Clinics on wheels – Bringing healthcare to patients in underserved communities
Sotatercept improves exercise capacity in patients with PAH
Fixed-dose macitentan plus tadalafil superior to either agent alone in PAH
Immediate complete revascularisation non-inferior to staged complete revascularisation
RENOVATE-COMPLEX-PCI results support intravascular-guided PCI for complex lesions
No need to restrict vigorous exercise in selected HCM patients?
No difference in CV outcomes between PET or CMR and SPECT
Benefits of MitraClip sustained to 5 years in COAPT trial
Transcatheter repair for patients with tricuspid regurgitation
Minimally invasive versus conventional sternotomy for mitral valve repair
Durable benefits of TAVR versus surgical aortic valve replacement in aortic stenosis patients
PCI not better than GDMT in severe ischaemic cardiomyopathy
Anticoagulation in non-critically ill hospitalised COVID patients
Statins associated with reduced heart dysfunction from anthracyclines
Multifaceted strategy improves prescription of therapies for diabetes and ASCVD
Bempedoic acid benefits statin-intolerant patients at high cardiovascular risk
Evolocumab improves coronary plaque morphology in stable CAD
Inflammation stronger predictor of MACE than cholesterol levels
Oral PCSK9 inhibitor significantly lowers LDL-C
Baxdrostat in patients with uncontrolled hypertension
Hormone therapy for gender dysphoria associated with increased CV risk
Pulsed-field ablation appears safe and effective for atrial fibrillation
Half-dose tenecteplase safe and effective for STEMI without timely PCI
Key correlates of incident dementia identified in the MESA study
Surgery saves lives in patients with oesophageal fistula
MANIFEST-PF: Good results for the pentaspline PFA catheter
POWER FAST III: High-power, short-duration radiofrequency ablation for AF
High-power, short-duration ablation linked to a higher stroke risk
Early or delayed ablation for AF?
CEASE-AF meets primary endpoint in persistent AF
Promising results for Marshall Plan ablation strategy
Can ICD-EG-derived information improve ventricular tachycardia ablation outcomes?
Prolonged ECG monitoring detects relevant arrhythmias in HCM
Does adaptive pacing work in patients with HF, LBBB, and intact AV conduction?
Can we identify patients who may not benefit from ICD therapy?
Statins display benefits for AF patients in a large population-based study
ANTWERP score selects HF patients for AF ablation
Epicardial ablation successful in Brugada syndrome
Highly increased risk of arrhythmias after mechanical ventilation for COVID-19
Top 14 Medical Innovations for 2022
Torsemide not superior to furosemide after hospitalisation for heart failure
IRONMAN failed primary endpoint but shows potential long-term benefits of iron repletion in HF patients
Up-titration of HF therapies following HF discharge saves lives
The endothelin system: a new target for resistant high blood pressure
Can renal denervation lower BP on top of antihypertensive drugs?
Quadruple, ultra-low-dose treatment did not meet primary endpoint in hypertension
Mindfulness programme contributes to office blood pressure lowering
Grafting with the radial vein: an underrated option in CABG surgery?
Methylprednisolone does not reduce risk of adverse outcomes in infants undergoing heart surgery
Extracorporeal membrane oxygenation not superior to conservative therapy in cardiogenic shock
Surgery with adequate saphenous vein partly better than endovascular treatment in CLTI
First-line ablation limits progression to persistent AF
Doubling the dose of self-administered etripamil terminates PSVT
Digitally delivered cognitive behavioural therapy successful in type 2 diabetes
Empagliflozin reduces risk of kidney disease progression and CV events in patients with CKD
RESPECT-EPA misses primary endpoint but hints towards improvements in CV outcomes by EPA
Pemafibrate fails to reduce cardiovascular events in diabetes but may benefit the liver
Olpasiran leads to dramatic reductions in Lp(a) concentrations
Dietary supplements not effective in lowering LDL-C, use of low-dose statins encouraged
No sex differences in lipid-lowering effect and treatment benefit of PCSK9 inhibitors
‘No’ to routine use of rivaroxaban in outpatients with COVID-19
COVID-19 pandemic: Older adults and those affected by the delta variant experienced increased cardiovascular morbidity and mortality
COVID-19 mRNA vaccination does not amplify risk of cardiovascular hospitalisation
Higher LDL-cholesterol levels linked to higher CVD mortality risk in the elderly
AF: Moderate alcohol intake possibly associated with a reduced mortality risk
Periodontitis: An independent risk factor for AF
VICTORION-INCEPTION: inclisiran immediately after ACS for secondary prevention
ORION-3: long-term inclisiran safe and feasible
Sponsored content – staggering results from Trial 21487PH
Old dogs, new tricks: Acetazolamide plus loop diuretics improves decongestion
No effect of neprilysin inhibition on cognition
Dapagliflozin DELIVERs for HFmrEF/HFpEF
Pooled analysis of DAPA-HF and DELIVER
Meta-analysis of DELIVER and EMPEROR-Preserved
Rheumatic heart disease-associated AF: standard-of-care holds ground
New anticoagulant safe and maybe effective: PACIFIC-AMI and PACIFIC-Stroke outcomes
AXIOMATIC-SSP: Reducing risk of ischaemic stroke with factor XIa inhibition?
Evolving evidence for P2Y12 inhibition in chronic coronary syndromes: PANTHER
Danish study suggests starting CVD screening before age 70
Polypill SECUREs win in secondary prevention in elderly
Long-term therapy with evolocumab associated with lower CV mortality
ARBs + beta-blockers may delay Marfan syndrome aortic root replacement
ENTRIGUE: Subcutaneous pegozafermin in severe hypertriglyceridaemia
First RCT evidence for use of AI in daily practice
AI-enhanced echography supports aortic stenosis patients
Smartphones for AF detection
Medical therapy versus PCI for ischaemic cardiomyopathy
Allopurinol disappoints in ALL-HEART
Conservative or invasive management for high-risk kidney disease patients with ischaemia?
Genotype-guided antiplatelet therapy in patients receiving PCI
Prevention of VT and sudden cardiac death: the new recommendations
New and first ESC cardio-oncology guideline
The 2022 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension
Cardiovascular assessment and management of patients undergoing non-cardiac surgery
Take hypertension medication anyTIME
BOXing out oxygen and blood pressure targets
Coronary CT angiography diagnostics compared head-to-head
High-dose influenza vaccine: mortality benefit?
FFR-guided decision-making in patients with AMI and multivessel disease
10% intensive cardiac care unit patients use Illicit drugs
Lifelong benefits of statin therapy
Signs of heart disease may be more subtle in women than in men
Polygenic score predicts sudden death in CAD
Causal link between haematopoietic loss of Y chromosome and cardiac disease unravelled
GALACTIC-HF: Omecamtiv mecarbil as option for HFrEF patients with low SBP
HELIOS-A: Vutrisiran meets exploratory endpoints
Patiromer helps HFrEF patients to optimise RAAS inhibitors without hyperkalaemia
FIDELITY: Cardiorenal benefits of finerenone, regardless of LVH status
DAPA-VO2: Rapid effect of dapagliflozin on peak VO2 in stable HFrEF
Significant improvement in BP from istaroxime, a novel non-adrenergic agent
SERENADE: Macitentan fails in HFpEF plus PAH
Ghrelin improves cardiac output in HFrEF
Combination of filgrastim and dutogliptin appears safe in STEMI
Cardiac contractility modulation therapy promising for patients with HFpEF
REBALANCE-HF: Encouraging observations for splanchnic nerve ablation in HFpEF
DAPA-HF: Dapagliflozin is safe and efficacious in frail patients
EMPEROR-Preserved: Empagliflozin stable across age groups
EMPULSE: Empagliflozin delivers rapid and clinically meaningful decongestion
Dapagliflozin performs consistently across LVEF in HF
Cardiac wasting relevant for clinical outcomes in cancer
Urocortin-2 a potential treatment target for HFpEF
Should ATTR-CM be added to the differential diagnosis of patients with HF?
Delayed initiation of novel GDMTs associated with adverse outcomes in HF patients
POISE-3: Tranexamic acid for non-cardiac surgery
Invasive management of NSTEMI improves outcomes in chronic kidney disease
Longer time between COVID shots may protect young men from heart inflammation
Statin use tied to slower progression of arterial stiffness in Chinese adults
Use of statins for primary prevention tied to lower risk of hospitalization for COVID-19
POISE-3: Tranexamic acid for non-cardiac surgery
Treating chronic mild hypertension during pregnancy leads to better outcomes
New VOYAGER PAD data: Should patients with both PAD and CKD get rivaroxaban?
Alirocumab significantly reduces high-risk coronary plaques
Aggressive warming during non-cardiac surgery does not improve outcomes
DIAMOND trial: Patiromer lowers risk of severe hyperkalaemia
Replacing septal reduction therapy with mavacamten for HCM
Surprise outcome for SODIUM-HF
Sotagliflozin SCORED MACE benefit
Omecamtiv mecarbil does not impact exercise capacity of patients with HFrEF
Symptomatic obstructive hypertrophic cardiomyopathy: long-term mavacamten control
COMPLETE revascularisation improves angina-related QoL
Plot twist for negative FAME 3 results: early QoL benefits of PCI
1-year CLASP TR results support tricuspid regurgitation repair
Head-to-head: post-TAVR edoxaban not better than DAPT
Chocolate Touch vs Lutonix catheters
No FLAVOUR difference between FFR and IVUS for PCI guidance
Low-resource countries benefit from global STEMI initiative
Sodium thiosulfate ineffective at cardiac protection
ICM-guided management did not improve MACE after MI
PACIFIC-AF: Low bleeding rates for asundexian in atrial fibrillation
RCT-IVVE trial: Do HF patients benefit from annual flu shots?
TRANSLATE-TIMI 70: Primary endpoint met but safety concerns for vupanorsen
Lipoprotein(a) slashed by 98% in APOLLO trial
Dietary intervention from your supermarket
Letter from the Editor
Benefits of SGLT2 inhibitors may extend beyond HF-associated outcomes
Updates on anti-arrhythmic agents
Sex differences revealed in AF determinants and AF progression
Early rhythm-control therapy efficacious in men and women with AF
Progression in remote app-based monitoring of atrial fibrillation
First results of the POWER FAST III trial
Real-world safety results on pulsed-field ablation with pentaspline catheter
VANISH: Ablation reduces shock burden compared with anti-arrhythmic drug in ventricular tachycardia
Low AF recurrence rates after PVI using pulsed-field ablation
Pulsed-field ablation reduces neurocardiac damage versus cryoballoon ablation
Ultrasound-guided femoral venipuncture reduces complications in catheter ablation
Conduction system pacing potential alternative for biventricular pacing in heart failure
Left bundle branch area pacing is a feasible technique for HF and bradyarrhythmia
Focus on the efficacy of cardiac resynchronisation therapy in HF plus concomitant AF
RESET: No survival benefit of CRT-defibrillator over CRT-pacemaker in heart failure
Insertable cardiac monitors effective for AF detection in cryptogenic stroke
Cardiac magnetic resonance imaging improves prediction of post-MI sudden cardiac death
AI model accurately predicts sudden cardiac death in overall population
Developments in imaging tools for AF
Large impact of remote screening tool on sleep apnoea diagnoses in AF
AI model accurately discriminates between arrhythmias
Impact of AF screening on stroke prevention influenced by systolic blood pressure
‘Startling’ heart attack finding in COVID patients
Survival higher after septal myectomy vs alcohol ablation for hypertrophic cardiomyopathy
Post-pulmonary embolism impairment frequent, follow-up urged after acute PE
MRA use does not limit empagliflozin benefit in HF with preserved ejection fraction
Text-based gamification boosts physical activity in hypertensive postpartum women
ACS patients with several metabolic risk factors may benefit most from PCSK9 inhibitors
Once-daily triple combination pill may best usual care for high blood pressure
Co-prescribed PDE5 inhibitors and nitrates not tied to adverse outcomes
Ischemic-pattern LGE in idiopathic dilated cardiomyopathy might not reflect ischemia
Fewer than half of stroke patients receive indicated dual-antiplatelet therapy
Fewer than half of stroke patients receive indicated dual-antiplatelet therapy
Bone marrow activation tied to atherosclerosis, metabolic syndrome in seemingly healthy people
Inhaled flecainide promising for atrial fibrillation
Presenting heart attack symptoms may help predict outcome
Strong magnets in newer portable electronic devices may interfere with implanted defibrillators
ACC issues consensus document on cardiovascular consequences of COVID-19
Serious mental illness tied to increased CV risk, starting in young adulthood
Mammograms may provide clues to heart-disease risk in older women
Stroke-related brain death in young heart donors tied to higher recipient mortality
Predictors pinpointed for recurrent mitral regurgitation, worse outcomes after MitraClip use
CT as effective as invasive angiography for guiding treatment of stable chest pain
Stress tests unreliable at detecting left main disease in moderate/severe ischemia
Study challenges troponin limits for determining heart damage after cardiac surgery
Myocardial fibrosis measures may help decisions about electronic device implantation
Early-life trauma tied to ECG changes indicating risk of arrhythmia during mental stress
Ross procedure tops prosthetic aortic valve replacement in younger adults
More-intensive statin-based therapies may be warranted for secondary stroke prevention
Anesthesiology handover during cardiac surgery associated with increased mortality
Normal NT-proBNP levels tied to low clinical risk in asymptomatic, nonsevere aortic stenosis
Elevated lipoprotein(a) linked with cardiovascular risk in patients with high coronary calcium
Endovascular baroreflex amplification appears safe, effective in resistant hypertension
Coronary-calcium score can help tailor treatment for severe hypercholesterolemia
New tool predicts mortality after percutaneous mitral-valve repair
NOAC could be better than warfarin in diabetes patients with atrial fibrillation
Anxious men face earlier decline in cardiometabolic health
Lower 5-year death rate with oral versus IV antibiotic therapy for endocarditis
Endovascular therapy found effective for larger cerebral infarctions
Conflicting periprocedural MI definitions impact clinical practice, research
Dapagliflozin improves stroke volume in patients with HFrEF
Shortcomings and solutions for the management of young patients with hypercholesterolemia
The scope of remote healthcare in hypertension and hyperlipidaemia
Reduction in atrial arrhythmias in patients with CIED on SGLT2 inhibitors
Inclisiran Lowers Cholesterol Across All BMI groups
AHA: Biomarker highly predictive of dapagliflozin response in HFrEF
Pilot trial shows potential benefit of stem-cell therapy in microvascular dysfunction
Apixaban plus P2Y12 inhibitor likely best for AF after ACS or PCI
Whether treated with CABG or PCI, heavily calcified lesions tied to higher mortality
AI-powered, ECG-enabled stethoscope detects heart failure in primary care
2021 Guideline for Chest Pain: Top 10 takeaways
Accurate ejection fraction assessment in paediatric patients via artificial intelligence
Concomitant tricuspid annuloplasty reduces treatment failure in moderate tricuspid regurgitation
Blood pressure control disrupted during the pandemic
Icosapent ethyl did not reduce the risk of hospitalisation in COVID-19
Neutral effect of P2Y12 inhibitors in non-critical COVID-19 hospitalisations
COVID-19 mRNA vaccination benefits outweigh the risk for myocarditis
Long-term reduced risk of CV events with ticagrelor plus aspirin after CABG
Early surgery outperforms conservative management in asymptomatic severe aortic stenosis
External support device for SVG grafts in CABG surgery shows promise
Rivaroxaban regimen beneficial after revascularisation for claudication
LIBERTY 360 shows quality-of-life improvements after peripheral vascular intervention
Deficient treatment outcomes after PVI in Black and low-income adults with PAD
REDUCE-IT: Cardiovascular risk reduction with icosapent ethyl in PAD
Ticagrelor cessation: early CABG non-inferior to delayed surgery
Distinguishing patients before AMI based on plaque morphology
Empagliflozin efficacious in HF patients with preserved ejection fractions ≥50%
EMPULSE: Empagliflozin improves outcomes of acute heart failure
CHIEF-HF: Canagliflozin improves health status in heart failure
DREAM-HF: MPC therapy for HFrEF did not meet primary endpoint
Therapeutic approaches in heart failure with diabetes
Remote healthcare programme improves hypertension and lipid control
Novel oral PCSK9 inhibitor shows promising results for hypercholesterolaemia
REVERSE-IT: Interim analysis shows promising effect of bentracimab on ticagrelor reversal
No significant effect of aspirin on reducing cognitive impairment
Milvexian phase 2 data supports safety and efficacy for VTE prevention after total knee replacement
Network meta-analysis observes no clear effect of eicosapentaenoic acid on CV outcomes
New developments in remote diagnostics and monitoring of AF
Head-to-head: Efficacy of dabigatran versus warfarin on cognitive impairment
Posterior left pericardiotomy safe and effective in reducing atrial fibrillation
LAA ligation did not reduce recurrent atrial arrhythmias in persistent AF
Equal benefits of early rhythm control in AF subtypes
Cannabis use associated with elevated cardiovascular disease risk
Interrogating cardiac implants after death reveals valuable details about patients and devices
Hearts from donors after circulatory death appear highly suitable for transplant
QoL better in most patients after transcatheter tricuspid-valve repair
Bedside ultrasound detects central venous congestion in patients with heart failure
Sex-hormone-binding globulin a potential biomarker for heart risks in men
Dapagliflozin tied to reduction in new-onset diabetes in patients with CKD, heart failure
Mixed results with metoprolol in obstructive hypertrophic cardiomyopathy
Carefully selected patients can go home the day after PCI for STEMI
Support for adapted D-dimer thresholds for ruling out pulmonary embolism
More promising data on mavacamten for hypertropic cardiomyopathy
Apixaban tops rivaroxaban for repeat-VTE protection in real-world analysis
Extracoronary vascular events likely rare after spontaneous coronary artery dissection
The scope of remote healthcare in hypertension and hyperlipidaemia
Cardiopulmonary exercise test helps define the cause of unexplained dyspnea in COVID long-haulers
Recurrent VTE more common than thought with isolated subsegmental pulmonary embolism
Evidence for smoking, insomnia as modifiable risk factors for intracranial aneurysm, hemorrhage
Atrial fibrillation symptoms less likely to be noticed by patients with diabetes
Women with breast cancer at increased risk for developing atrial fibrillation
Coffee’s physiological effects are mixed, randomized trial shows
Fitbit algorithm reliably detects atrial fibrillation
Time from stopping blood thinner to CABG can be safely shortened
Support for early valve replacement in severe aortic stenosis without symptoms
Low-urgency heart-transplant recipients more likely to receive organs from higher-risk donors
Secondary antibiotic therapy offers 10-fold lower risk of rheumatic heart disease progression
Urine sample study shows 18% increase in heart risk for every 1,000 mg of sodium in diet
Benefits of adding tricuspid repair to mitral-valve surgery tempered by pacemaker risk
A new bicaval-valve implant could improve outcomes in some heart-transplant patients
After a heart attack, sacubitril-valsartan no better than ramipril for heart-failure prevention
No benefit to skipping alteplase before endovascular treatment
Cryptogenic-stroke features and cancer status may be linked
Bypass still better than stenting in severe heart disease – study
Novel index likely predicts outcomes in heart failure with severe secondary mitral regurgitation
Coronary calcium score alone of limited value in younger patients with suspected CAD
Strategy to assess tafamidis efficacy in transthyretin amyloid cardiomyopathy proposed
Stimulant use among older adults ups risk of cardiac harm in the short-term
Diagnoses of wild-type transthyretin amyloid cardiomyopathy rising, but often late
Breathing problems: the most frequently reported symptom before cardiac arrest
Lay responders can improve survival in out-of-hospital cardiac arrest
Rivaroxaban improves clinical outcomes in discharged COVID-19 patients
COVID-19: Thromboembolic risk reduction with therapeutic heparin dosing
Long COVID symptoms – Is ongoing cardiac damage the culprit?
VOYAGER PAD: Fragile or diabetic patients also benefit from rivaroxaban
NATURE-PCSK9: Vaccine-like strategy successful in lowering CV events
Polypill: A successful tool in primary prevention
Smartphone app improves BP control independent of age, sex, and BMI
QUARTET demonstrates that simplicity is key in BP control
Salt substitutes: a successful strategy to improve blood pressure
Valsartan seems to attenuate hypertrophic cardiomyopathy progression
Dapagliflozin reduces incidence of sudden death in HFrEF patients
Empagliflozin: First drug with clear benefit in HFpEF patients
CardioMEMS: neutral outcome but possible benefit prior to COVID-19
Cardiac arrest without ST-elevation: instant angiogram does not improve mortality
Older hypertensive patients benefit from intensive blood pressure control
Antagonising the mineralocorticoid receptor beneficial for patients with diabetes and CKD
2021 ESC Guidelines on Heart Failure
2021 ESC/EACTS Guidelines on Valvular Heart Disease
2021 ESC Guidelines on Cardiac Pacing and Cardiac Resynchronisation Therapy
2021 ESC Guidelines on Cardiovascular Disease Prevention
‘Broken heart’ syndrome rising in women even before pandemic
Adherence to sacubitril/valsartan for heart failure tied to risk of readmission, death
Remote heart-failure care tied to less diagnostic testing, less guideline-directed therapy
Most women born with heart defects can become pregnant and give birth safely
TAVR benefits likely similar in trials and real world, and maybe in some bicuspid cases
NAFLD may be independent risk factor for cardiovascular morbidity and mortality
‘Reassuring’ clinical outcomes with pacemaker implantation after TAVR
Stroke risk rises transiently with AF episodes in patients with implanted cardiac devices
Increased risk of death in cardiac wait list patients seen early in pandemic
Healthy sleep patterns tied to healthier heart rhythms
Continuous monitoring detects atrial fibrillation up to 30 days after discharge
Empagliflozin benefits tied to drop in NT-proBNP levels in heart-failure patients
Young women who receive left-sided radiation for breast cancer at higher risk for heart disease
Monitoring PA pressure likely curbs heart-failure hospitalization in obese
ESC 2021 Highlights Podcast
‘Considerable’ bleeding risk with extended anticoagulant therapy after first unexplained VTE
PCSK9 inhibitors may not be sufficient to curb atherosclerotic cardiovascular disease
Adults 65+ benefit from LVADs, with fewer complications than younger people
Elevated lipoprotein(a) plus high sensitivity CRP levels raise cardiac risk
Machine-learning model helps predict short-term response to cardiac-resynchronization therapy
Early switch to DOAC appears safe and effective for intermediate-risk pulmonary embolism
Health status, exercise capacity help predict outcomes in heart failure with mitral regurgitation
Drug prevents some heart-failure hospitalizations when ejection fraction is preserved
At age 60 to 80, systolic pressure of 110 to <130 produces clear health benefits
Drinking alcohol tied to increased atrial fibrillation risk hours later
Dual-antiplatelet therapy only necessary for one month after implantation of drug-eluting stent
Edoxaban not inferior to vitamin K antagonists after TAVR, but bleeding risk higher
Quick catheterization may not be wise in cardiac-arrest survivors with no ST-segment elevation
Salt substitution found to reduce death, stroke, heart events by 12% to 14%
EMPORER-Preserved: Interview with Prof. Stefan Anker
Colchicine likely curbs MACE risk regardless of history, timing of prior acute coronary syndrome
New pacing method shows early promise for advanced peripheral-conduction disease
REFILE-Progressive rehabilitation improves outcomes for elderly heart failure patients
Women still excluded from cardiovascular clinical trials
Delaying diabetes onset a target for heart-failure prevention
Iron substitution improves LVEF in intensively treated CRT patients with iron deficiency
Novel mineralocorticoid receptor antagonist effective irrespective of HF history
Iron substitution in iron-deficient HF patients is highly cost-effective
Omecamtiv mecarbil might be less effective in patients with atrial fibrillation or flutter
Vericiguat effective irrespective of atrial fibrillation status
Baroreflex activation: a novel option to improve heart failure symptoms
Beta-blocker withdrawal to enhance exercise capacity in heart failure?
Inconclusive results for dapagliflozin treatment in heart failure
Computerised cognitive training improves cognitive function in HF patients
Real-world study suggests sacubitril/valsartan benefits elderly patients with HF
Proenkephalin: A useful biomarker for new-onset heart failure?
Weight loss associated with increased mortality risk in heart failure patients
Echocardiographic parameters linked to dementia diagnosis
Telemedicine: Every light has its shadow
COVID-19-related HF: from systemic infection to cardiac inflammation
Increased COVID-19 mortality in patients with cardiorenal comorbidity
Myocardial infarction outcomes were significantly affected by the pandemic
Empagliflozin linked to lower cardiovascular risk and renal events in real-world study
Efficacy of dapagliflozin and empagliflozin not influenced by diabetes status
TAPSE effective biomarker associated with high-risk of severe COVID-19
COVID-19 in AF patients with HF: no higher mortality but longer hospital stay
Biomarker panel predicts SGLT2 inhibitor response
Psychoactive substances put young people at risk of cardiovascular disease
Heart failure patients might be at an increased risk for head and neck cancer
The challenge of improving the quality of life of heart failure patients
Trastuzumab associated with cardiotoxicity in breast cancer
Authors commenting on RCTs of invasive cardiovascular interventions often have financial conflicts
Decline in hospitalizations for heart attack and stroke persisted through 2020
Repeat TAVR an ‘important’ option for aortic-valve re-intervention
3D-bioprinted cardiac patches promising for myocardial regeneration after heart attacks
No difference between treatment with milrinone, dobutamine in cardiogenic shock
DOACs superior to aspirin after left ventricular arrhythmia ablation
Protein profiles may predict stable, progressive chronic lymphocytic leukemia
Can a glass of wine a day keep a-fib away?
Atrial fibrillation after SAVR or TAVR tied to poorer outcome
Success rates for coronary re-access after TAVR higher in patients with short stent-frame prostheses
Progressive rehabilitation improves outcomes for elderly heart failure patients
Physical activity tied lower all-cause mortality after ICD implantation
Apixaban has benefits over other DOACs in frail adults with atrial fibrillation
Factor XI inhibitor cuts risk of postoperative venous thromboembolism by about 80%
TAVI safe and effective in patients with inflammatory bowel disease
New score predicts perioperative mortality of adult congenital heart disease surgery
Genotype-based strategy reduces thrombotic events after heart-device implant
Adding rivaroxaban to aspirin may help some CAD, PAD patients live longer
Athletes may have doubled A-fib risk compared to general public
Dapagliflozin fails to show a significant protective effect in COVID-19
Favourable outcomes with transcatheter atrial appendage occlusion
PARADISE-MI: Sacubitril/valsartan not superior to ramipril in reducing HF events
STRENGTH trial fails to demonstrate cardioprotective effect of omega-3 fatty acids
Men and women benefit equally from early aspirin withdrawal following PCI
Apixaban outcomes similar to current standard of care following TAVR
No difference in ischaemic risk or bleeding with low vs high-dose aspirin for secondary prevention: Lessons and questions from the ADAPTABLE trial
Etripamil nasal spray significantly improves PSVT-related symptoms
Similar outcomes with fractional flow reserve and angiography-guided revascularisation
Evinacumab lowers triglyceride levels in severe hypertriglyceridaemia
Rivaroxaban reduces total ischaemic events after peripheral artery revascularisation
Therapeutic anticoagulation not superior to prophylactic anticoagulation in COVID-19
Older adults with heart failure benefit from rehabilitation programme
Moderate hypothermia not superior to mild hypothermia following out-of-hospital cardiac arrest
Quality improvement intervention fails to improve care for patients with heart failure
TALOS-AMI: Exploring outcomes after switching to clopidogrel versus ticagrelor at 1 month from MI
Clopidogrel monotherapy associated with better net outcomes relative to aspirin monotherapy 6-18 months after PCI
Sacubitril/valsartan does not reduce NT-proBNP versus valsartan alone in HFrEF
Preliminary results encouraging for EVOQUE tricuspid valve replacement
Novel use of ivabradine in reversible cardiomyopathy
Atorvastatin does not reduce mortality in COVID-19
Health equity and the role of the cardiologist: 7 priorities to consider
Ablation-based rhythm control as effective as rate control in AF and HF
Finerenone reduces the risk of AF onset in patients with CKD and diabetes
Better outcomes with invasive strategy if anatomic complete revascularisation is possible
With hypertrophic cardiomyopathy, age and BMI among predictors of AFib events
Ablation bests drug therapy for minorities with afib in North America
PCI for chronic total occlusion more successful after coronary CTA
Echocardiography identifies risks of arrhythmia, cardiac failure in pediatric myocarditis
Statins not tied to incident dementia or cognitive decline in older adults
Wireless, resorbable pacemaker may help patients who need only temporary pacing
LV lateral wall function may be marker of need for resynchronization in LBBB
Experimental drug lowers risk of cardiovascular, renal events in type 2 diabetics
Despite successful reversal in many, DOAC-prompted bleeding fatal in some
Boosting cardiac output via TAVI may help preserve kidney function
Elderly heart transplant patients have 5-year survival similar to younger recipients
Intravascular lithotripsy promising vessel-prep strategy for peripheral-artery calcification
Sotagliflozin reduces disease burden in diabetes with worsening heart failure
Lipid management lacking in patients with peripheral-artery disease
ECG biomarker identifies AFib patients most likely to benefit from electrical stimulation
Presumed sudden cardiac death among HIV-infected often not due to coronary-artery disease
Individualised approaches key to success in resynchronisation therapy non-responders
Antiarrhythmic drug treatment in children: evidence-based recommendations
The importance of cardiac imaging in patients with congenital heart disease
EHRA expert statement on pacemakers and intracardial devices: “watch out for the little old lady”
5-Year efficacy of subcutaneous implantable cardioverter defibrillator
EHRA Practical Guide on cardiac imaging in electrophysiology
Novel diagnostic score accurately differentiates between athlete’s heart and ARVC
The precordial R-prime wave: a discriminator between cardiac sarcoidosis and ARVC
Limited added value of ECG-based mortality prediction in COVID-19 patients using machine learning
Early rhythm-control ablation: insight from the CHARISMA registry
Personalised pulmonary vein isolation procedure feasible and effective
Pulmonary vein isolation: cryoballoon non-inferior to radiofrequency ablation
Pulmonary vein isolation lesions plus personalised methods shows promising results
Predictors of young-onset atrial fibrillation
RACE 3 long-term results show fading benefit of targeted therapies in AF and HF
Deep dive into EAST-AFNET 4 results on early rhythm-control in atrial fibrillation
Cryo-FIRST study: improved AF and QoL outcomes with cryoballoon versus drug therapy
STROKESTOP: Benefits of systematic screening for atrial fibrillation
DOACs and bleeding: the role of antidotes
Going directly to angiography tied to better outcomes after transfer for thrombectomy
2021 EHRA practical guide: DOACs in pre-operative and bleeding patients
New transcatheter tricuspid-valve repair device helps close larger coaptation gaps
Lung-cancer screening can spot people at high risk for aortic stenosis
Prophylactic pacemaker placement may streamline TAVR hospitalization in some patients
Troponin testing presents unique challenges in patients with kidney impairment
Pericardial fat tied to increased heart failure risk, particularly for women
Hypertension in pregnancy tied to increased risk of stroke years later in offspring
PCI for in-stent chronic total occlusion shows in-hospital success
Accelerometer-derived physical activity tied to atrial fibrillation risk
Interventions after TAVR may benefit some with mitral regurgitation
Benefits of multivessel PCI unclear in patients with NSTEMI and cardiogenic shock
Higher systolic blood pressure likely boosts early heart disease risk in adults born preterm
Stage 1 hypertension in early 40s a stronger ACS risk factor for women than men
Finerenone may delay onset of atrial fibrillation in at-risk patients
Bleeding, vascular complication rates lower when transradial PCI replaces transfemoral PCI
Benefits of transcatheter repair of mitral regurgitation maintained at 2 years – CLASP study
Cardiac-myosin activator yields greatest benefit in severe heart failure
Strong case for rivaroxaban plus aspirin after lower-extremity revascularization in PAD
Finerenone may reduce risk of AF onset in patients with CKD and diabetes
Evinacumab lowers triglyceride levels in severe hypertriglyceridaemia
Pulmonary artery thrombectomy a safe alternative to thrombolytics
Atorvastatin does not reduce mortality in COVID-19
Therapeutic anticoagulation inferior to prophylactic anticoagulation in COVID-19
Moderate hypothermia not superior to mild hypothermia following out-of-hospital heart attack
TALOS-AMI: Superior outcomes clopidogrel over ticagrelor following 1-month DAPT
Dapagliflozin fails to show a significant protective effect in COVID-19
Rivaroxaban reduces total ischaemic events after peripheral artery revascularisation
Similar outcomes fractional flow reserve and angiography-guided revascularisation
Clopidogrel superior to aspirin as monotherapy after DAPT in HOST-EXAM trial
Older adults with heart failure benefit from rehabilitation programme
Afib patients benefit when left-atrial-appendage occlusion added to their heart surgery
Higher bleeding risk in women after PCI mostly due to baseline sex differences
Aggressive rehabilitation helps frail heart-failure patients
Aspirin dose of 81 mg offers comparable protection to 325 mg in secondary prevention
Low-dose as effective as regular strength aspirin in preventing CV events
Apixaban outcomes comparable with current standard of care following TAVR
Sacubitril/valsartan does not lower risk of heart failure versus ramipril
Mavacamten emerges as a new therapy for hypertrophic cardiomyopathy
Men and women benefit equally from early aspirin withdrawal following PCI
Favourable outcomes with transcatheter atrial appendage occlusion
Mavacamten significantly improves QoL of patients with hypertrophic cardiomyopathy
Atypical MI symptoms tied to higher mortality, poorer emergency response
Anticoagulation common near end of life in dementia patients with AFib
Pulsed field ablation effective against paroxysmal atrial fibrillation
Catheter ablation with mapping likely bests conventional approach to tachycardia over the long-term
Catheter ablation likely more effective than drugs for paroxysmal atrial fibrillation
Hemostatic patch promises to improve cardiac cath-lab efficiency
Occupational physical activity tied to major adverse cardiovascular events, mortality
Patients on hormonal therapies for cancer should be monitored for heart risk – AHA
Many patients on DOACs receive concurrent non-indicated aspirin tied to bleeding risk
Dapagliflozin benefits in type-2 diabetes consistent across kidney-function groups
Tocilizumab boosts myocardial salvage in acute STEMI
Low risk of delayed brain bleed after blunt head trauma in older people on DOAC therapy
AHA 2020: Polypill + aspirin prevents cardiovascular events
AHA2020: Inclisiran effective across age and genders for hyperlipidemia
No age cap for lipid-lowering therapy
PCSK9 inhibition as primary prevention for VTE: Is it LDL or Lp(a)?
Permanent pacemaker implantation after TAVI likely lower in women than men
Riociguat an option for pulmonary arterial hypertension when PDE-5 inhibitors fail
Contraceptive and pregnancy planning essential in women with heart disease, experts advise
COVID-19 outcomes no worse with congenital heart disease
Sotatercept improves vascular resistance in pulmonary arterial hypertension in early trial
Remote antiarrhythmic drug loading may be feasible – pilot study
KCCQ-OS more likely than NYHA class to detect health status changes in heart failure
DOACs safer, more effective than warfarin in valvular atrial fibrillation
‘Silent’ heart attack tied to risk of future stroke in older adults
Retinal damage may signal risk for stroke and dementia
Substantial discordance between troponin assays for ACS risk stratification
Mobile stroke units improve outcomes in acute ischemic stroke
Diuretic effect may not mediate most empagliflozin benefits in heart-failure patients
Best medical care often lacking in critical limb ischemia
Intensive hypertension therapy not tied to worse sexual health.
ApoB more likely to predict mortality risk than LDL-C or non-HDL-C in statin-treated patients
Endovascular approach to diabetic limb ischemia tied to lower hospital mortality, more amputations
Cancer patients have higher readmission rates for heart attack, bleeding after PCI
Link between cardiovascular-risk management and dementia protection remains elusive
‘Alexa, How is my heart?’ Using smart speakers to monitor cardiac rhythm
Screening with wearable ECG increased AF detection 10-fold in hypertensive older adults
Ivabradine helpful in postural orthostatic tachycardia syndrome
Women with heart disease often fare better with a female physician
Subclinical atherosclerosis, CVD risk factors tied to brain hypometabolism
PAD: Rivaroxaban reduces VTE risk after revascularisation
Sotatercept: potential new treatment option for PAH
Finerenone lowers CV events in diabetic CKD patients
Mavacamten effective in obstructive hypertrophic cardiomyopathy
Children exposed to tobacco smoke have worse heart function as adults
Transgender people have unaddressed heart disease risks
Rilonacept reduces risk of pericarditis recurrence
Intensive blood pressure lowering benefits older adults
Dobutamine versus milrinone in cardiogenic shock
Longer chest compression pause worsens outcomes after paediatric IHCA
Ticagrelor/aspirin reduces stroke risk in patients with ipsilateral cervicocranial plaque
AF monitoring following cardiovascular surgery
Extra imaging reveals cause of MINOCA in women
Ticagrelor not superior to clopidogrel after elective PCI
No benefit from omega-3 fatty acids after recent MI
PIONEER III trial: Drug-eluting stents comparable
Omecamtiv mecarbil improves outcomes in HFrEF-patients
IV iron reduces HF hospitalisation
Dapagliflozin reduces renal risk independent of CV disease status
“Strongly consider an SGLT2-inhibitor in most T2DM patients”
Additional HFrEF education and patient-engagement tools
Pre-diabetes tied to increased stroke risk with nonvalvular atrial fibrillation
Clever trial design gets patients back on statins: the SAMSON trial
Polypill plus aspirin reduces cardiovascular events
Lowering LDL cholesterol in older patients is beneficial
No CV benefit from omega 3 in high-risk patients
Safety and efficacy of inclisiran for hypercholesterolemia
Remote risk management programme effective and efficient
Healthy lifestyle lowers mortality irrespective of medication burden
Vitamin D or omega 3 fatty acids do not prevent AF
Active screening for AF improves clinical outcomes
AF screening in older adults at primary care visits
Fewer CV complications than expected in AHA COVID-19 Registry
Worse COVID-19 outcomes in younger obese patients
Effects of CVD in hospitalised COVID-19 patients
Meta-analyses: ACEI/ARB and COVID-19
Unfavourable outcomes for COVID-19 patients with AF and atrial flutter
High-dose influenza vaccine in patients with CVD
Long-term mortality after coronary-artery occlusion may not depend on recanalization status
High blood pressure likely to be causally linked to atrial fibrillation
Transcatheter valve-repair system promising against tricuspid regurgitation
Common genetic variants, modifiable risks implicated in hypertrophic cardiomyopathy
No need to adjust rivaroxaban dose for overweight heart disease patients
Benzodiazepines given for ACS anxiety, pain may trigger posttraumatic stress symptoms
SAVR an option for many low-risk patients excluded from clinical trials
Calcium chloride during CABG curbs subsequent atrial fibrillation
Left atrial appendage occlusion tied to less afib bleeding, mortality vs DOACs
Mortality higher in real-world LVAD recipients ineligible for clinical trials
DASH-diet intervention might slow progression of nonobstructive coronary atherosclerosis
Could statins protect the heart from breast-cancer chemotherapy?
Remote intensive management by allied healthcare providers safe in low-risk MI patients
TTR V122I variant linked to adverse cardiac mechanics in middle-aged Black Americans
Higher levels of diet-derived antioxidants don’t protect against heart disease
Pregnancy safe after arterial switch operation for transposition of the great arteries
Treating inpatient hypertension likely does more harm than good: study
Study shows no mortality increase if paclitaxel coats peripheral-artery devices
LVAD centers linked to less mortality from cardiogenic shock
Study links fracking operations to worsening heart failure
AI-driven body-composition analysis predicts heart attack and stroke better than BMI
Claudication often recurs after endovascular treatment without risk-factor management
Sedentary time tied to heart failure hospitalization in postmenopausal women
SGLT2 inhibitor reduces filling pressure in HFrEF patients
VLDL, remnant cholesterol may help assess cardiovascular risk
Transcatheter valve replacement curbs tricuspid regurgitation in many
TAVR may be best choice for valve replacement after mediastinal radiation
Complete hemodynamic profiling tied to lower mortality from cardiogenic shock
ECMO-resuscitation tied to better survival in out-of-hospital cardiac arrest
Studies show cardiovascular benefit with sotagliflozin
Cryoablation Afib studies show better first-line outcomes than drug therapy
Correcting iron deficiency protects heart failure patients from repeat hospital stay
Rivaroxaban not inferior to warfarin for afib patients with artificial mitral valve
Amgen drug shaves 8% off risk of heart-failure event or heart death
Heart polypill cuts cardiovascular disease risks by 21% over placebo in primary prevention trial
Direct oral anticoagulants may best vitamin K agonists for post-TAVR a-fib
Obesity independently tied to longer survival after cardiac resynchronization
Cryoballoon supplement to pulmonary-vein isolation curbs AF recurrence
2020 Atrial Fibrillation Guidelines
2020 Non-ST-Segment Elevation Acute Coronary Syndromes Guidelines
2020 Sports Cardiology and Exercise in Cardiovascular Patients Guidelines
2020 Adult Congenital Heart Disease Guidelines
SGLT2 inhibitor improves cardiovascular outcomes in heart failure patients
First-in-class cardiac myosin inhibitor effective in obstructive hypertrophic cardiomyopathy
Reduced cardiovascular outcomes with early rhythm control
Trimetazidine after successful PCI not associated with fewer cardiac events
POPular TAVI: Aspirin-only antiplatelet strategy?
Reduced NT-proBNP in HFpEF with sacubitril/valsartan
DAPA-CKD: Dapagliflozin improves CKD survival ± diabetes
Low-dose colchicine reduces CV death and ischaemic events in coronary disease
Similar outcomes sPESI and HESTIA for pulmonary embolism triage
Antihypertensives also reduce CV risk in people with normal blood pressure
COVID-19: Continuing versus suspending ACE inhibitors and ARBs
Drug initiation strategy not associated with increased use of oral anticoagulants
Restrictive blood transfusion non-inferior and cost-effective strategy
Increased mortality with colchicine in patients with ACS
Rivaroxaban protects limbs and ischaemic events in CAD-PAD patients
Antisense APOC3 oligonucleotide lowers triglyceride and atherogenic lipoproteins
Antisense ANGPTL3 lowers triglycerides
Reduced progression of coronary atherosclerosis with icosapent ethyl
Digoxin improves symptoms in stable patients with permanent AF
SGLT2 inhibitor ertugliflozin shows similar mortality but fewer HF hospitalisations
Risk factors for thromboembolism and bleeding in COVID-19: lessons from Wuhan
The Yale COVID-19 Cardiovascular Registry
COVID-19 treatments and the importance of randomised trials
New model quantifies cardiac arrest risk in Brugada syndrome
Serum omega-3 fatty acids tied to improved STEMI prognosis
Mortality lower after coronary bypass surgery than after percutaneous interventions
Intravascular lithotripsy safely treats severely calcified coronary-artery disease
Surgical valve explantation after TAVR tied to high short-term mortality
Durability of newer TAVR valve comparable to that with SAVR
After heart attack, men and women face more-similar cardiovascular risks
Lipoprotein(a) levels tied to atherosclerotic heart disease risk
COVID-19-associated delays in aortic-valve replacement tied to worse outcomes
Clopidogrel cessation after atrial-septal-defect repair doesn’t boost migraine risk
Increased risk for cardiovascular disease seen with two or more menopausal symptoms
Ertugliflozin passes post-approval cardiovascular safety test
Treatment times of acute STEMI have increased with COVID-19 pandemic
Improvement of coronary-artery-plaque lipid-rich necrotic core seen with biologic therapy of psoriasis
Pesco-Mediterranean diet with fasting proposed to optimize heart health
Leadless cardiac pacemakers may be safely retrieved after several years
Surgical bleeding risk most important determinant of bleeding outcomes
Similar bleeding rates in patients with VTE and AF treated with DOACs
Physical rehabilitation improves health outcomes after pulmonary embolism
Guidelines adherence reduces bleeding risk after surgery and childbirth for VWD patients
Factor V Leiden mutation linked to atrial fibrillation
Increased rates of arterial thromboembolism in cancer patients
Residual pulmonary obstruction may predict risk of VTE recurrence
Less diagnostic delay in CTEPH diagnosis with novel algorithm
Risk of checkpoint inhibitor-associated thromboembolic events important for cancer prognosis
Fewer adverse events with ticagrelor monotherapy after 3 months DAPT
TWILIGHT sub-study: same outcomes for diabetes patients
Crosstalk between inflammation and coagulation in severe COVID-19 infections
TWILIGHT sub-study: complex PCI patients
COVID-19 associated with higher VTE rates relative to influenza
Therapeutic anticoagulation not associated with lower mortality rates in COVID-19 ICU patients
LAAO Watchman registry data positive
COVID-19 not associated with heightened VTE risk after discharge
Finding the sweet spot of anticoagulation in AF patients with ACS
Lower embryopathy risk with DOAC versus VKA during pregnancy
Higher thrombotic risk in NSCLC patient with ALK rearrangement
Novel gene therapy leads to normal FIX activity levels in severe haemophilia B
Haemophilia gene therapy: progress and obstacles
Recombinant factor VIII safe and effective in PUPs A-LONG study
Apixaban in AF patients with recent ACS/PCI: Drop aspirin after 30 days
Homozygous FH responds to alirocumab
Evinacumab significantly reduces LDL-C in homozygous FH patients
Higher serum levels of eicosapentaenoic acid correlate with reduced CV events
Quit smoking: vaping + counselling helps
TAVR safe and effective in low-risk bicuspid aortic stenosis patients
TAVR model reveals differences in hospital outcomes
TAVR versus surgery in older patients
Real-world evidence for MitraClip
2-year results show non-significant outcomes TAVR vs surgery in severe aortic stenosis
Renal denervation better than sham for blood pressure
Radial artery best for second bypass
PCI and CABG are equal in left main CAD
Infusion of ethanol in the vein of Marshall for persistent AF
Rivaroxaban and aspirin effective and safe for PAD patients
Subgroup analysis VOYAGER PAD
TAILOR-PCI misses endpoint but still provides valuable insights
Edoxaban: alternative to warfarin after surgical aortic or mitral valve procedures?
Bleeding reduction post-TAVI with OAC alone vs OAC + clopidogrel
Apixaban offers new perspective for cancer patients in need of anticoagulation
Rivaroxaban superior to enoxaparin in preventing VTE in non-major orthopaedic surgery
Mavacamten shows promising results in non-obstructive hypertrophic cardiomyopathy
Vericiguat shows beneficial effects in a very high-risk HF population
No role for sodium nitrite in out-of-hospital cardiac arrest
ACC.20/WCC Highlights Podcast Part 1 of 3
ACC.20/WCC Highlights Podcast Part 2 of 3
ACC.20/WCC Highlights Podcast Part 3 of 3
Aspirin alone best anti-clotting strategy after TAVI
Drop aspirin after 3 months in non-STEMI ACS patients on dual antiplatelet therapy
Icosapent ethyl plus statins reduces total plaque volume
RENAL-AF trial: Apixaban similar to warfarin
Full GALILEO results: Why did rivaroxaban fail after TAVR?
FUEL trial: Udenafil improves some exercise measurements in Fontan
Apple Heart Study: Not just for atrial fibrillation
Balloon-expandable better than self-expanding transcatheter heart valves
DAPA-HF: Dapagliflozin also good for heart failure patients without diabetes, of any age, or any health status
ORION-9: Inclisiran RNAi halves LDL in familial hypercholesterolaemia patients
Immediate coronary angiography after cardiac arrest does not improve survival
Early apixaban safe as secondary prevention of stroke from AF
New RNAi therapies to reduce triglycerides: 2 studies show favourable results
Complete revascularisation for obstructive non-culprit lesions with vulnerable plaque
Carvedilol does not improve exercise performance in Fontan patients
Colchicine: no difference in peri-procedural cardiovascular events 30 days post-PCI
Phase 3 BETonMACE trial did not meet its primary endpoint
PARAGON-HF: Benefits for women and lower ejection fraction
Targeting LDL-C <70 mg/dL is better than 100 mg/dL after stroke
Intra-aortic balloon pump better than Impella: new observational data
Inclisiran safely halves LDL-Cholesterol
Testosterone gel increases left ventricular mass
New guidelines on the prevention of cardiovascular conditions
RECOVERY: Benefit of early surgery in asymptomatic severe aortic stenosis
ISCHEMIA trial: Invasive treatment only better for angina burden
Colchicine prevents cardiovascular events
ESC guidelines on chronic coronary syndromes focus on lifestyle
Early rule-out alogrithm for MI patients proves safe and effective
Adding evolocumab to high-intensity statins in ACS patients reduces LDL-C substantially
Early vasodilation in acute HF does not improve outcomes
More severe coronary artery calcifications with VKA than NOAC
Long-term data confirm superiority of inter-hospital transport for primary PCI vs fibrinolysis
Omega-3 fatty acid supplements may offer cardiovascular protection
Beta-blockers reduce death in HF patients with moderate renal impairment
Complete revascularisation superior to culprit-lesion-only PCI
Decreasing use of preventive medication a few years after CABG
Ticagrelor in diabetic patients reduces CV events but increases major bleeding
Reduced doses rivaroxaban and apixaban may be beneficial to reduce renal impairment
Apixaban superior to VKAs for major bleeding, stroke/STE and all-cause mortality
The new ESC Guidelines dyslipidaemia: the lower the better
Fewer deaths and hospitalisations in HF patients with SGLT2-inhibitor dapagliflozin
Prasugrel superior to ticagrelor in reducing ischaemic events in ACS + planned invasive strategy
Inclisiran offers substantial LDL-C reductions in ASCVD patients
Catheter ablation reduces all-cause mortality risk in AF-HF patients
Salt substitution programme successful in lowering blood pressure
Scandinavian children with familial hypercholesterolemia are underdiagnosed and undertreated
Early use ICD after PCI shows beneficial effect on survival in patients at high risk of death after STEMI
HOPE 4 trial: Community-based intervention successful in reducing CV risk in hypertensive patients
Genetic testing non-inferior to standard drug treatment with regard to thrombotic events
Rivaroxaban monotherapy non-inferior to combination therapy in AF and stable CAD patients
Catheter ablation plays key role in 2019 ESC Guidelines on tachycardia
The Italian experience: DOAC more cost-effective than VKA
Real-world data shows catheter ablation in AF patients lowers risk of death and HF hospitalisation
No benefit of percutaneous reduction of secondary mitral regurgitation in HF patients over standard care
10-year follow-up shows no significant difference in all-cause death between PCI and CABG
PURE study: risk factors cardiovascular disease in low- and high-income countries
Similar MACE rates but higher all-cause mortality in PAD patients with diabetes
Lower rates stroke/SE with DOACs in frail non-valvular AF patients
Similar rates of stroke/SE associated with DOAC vs warfarin use in obese non-valvular AF patients: Results from an observational registry
TAVR superior and non-inferior to SAVR in low-risk patients
Convincing evidence of the role of icosapent in reducing subsequent CV events
Immediate angiography not better than delayed angiography in non-STEMI cardiac arrest patients
Frequent use of beta-blocker after HFpEF hospitalisations in elderly patients without compelling indications
Clopidogrel monotherapy after 1-month DAPT may be beneficial in stent patients
Ticagrelor monotherapy safe after dual antiplatelet therapy
Apixaban is safe and effective in real-world setting for treatment of venous thromboembolism
BNP still a reliable prognostic marker before and during sacubitril/valsartan treatment
P2Y12 inhibitor monotherapy is a novel antiplatelet strategy after short duration DAPT
High 5-year survival rates for older HF patients without initial severe comorbidity
Early discharge and home treatment feasible for low-risk pulmonary embolism patients
Higher incidence arrhythmia post-percutaneous closure of secundum ASD in patients >60 years
Diagnosing cardiac sarcoidosis with endomyocardial biopsies
Patients with polyvascular disease significantly undertreated with lipid lowering therapies
Unplanned hospital readmission is common after congenital cardiac surgery
Substantial impact of temporary interruptions of warfarin versus DOAC
DECLARE TIMI-58 trial shows benefits of dapagliflozin in high-risk subgroups
Letter from the Editor
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
Less bleeding and fewer hospitalisations with antithrombotic regimen with apixaban without aspirin
Smartwatch can detect atrial fibrillation with high degree of accuracy
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
Letter from the ESC Congress Programme Committee Chairs
Letter from the Advisory Board
Letter from the ESC Congress Programme Committee Chair
Interview with Prof. Mitja Lainscak
Letter from the ESC Congress Programme Committee Chair
Letter from the ESC Congress Programme Committee Chair
Letter from the ESC Congress Programme Committee Chair
Letter from the ESC Congress Programme Committee Chair
Letter from the Editor
Interview with Prof. Frank Ruschitzka
Letter from the Editor
Interview with Prof. Matthias Heringlake
Interview with Dr. Richard A. Chazal
Dermatology
Letter from the Editor
What’s new in acne?
Nearly all participants respond to deucravacitinib in lichen planopilaris study
Dupilumab in bullous pemphigoid
Breaking the cutaneous lupus loop with deucravacitinib
Active psoriatic arthritis: POETYK PsA-2 trial results
Upadacitinib efficacious in palmoplantar pustulosis
Delgocitinib gets the upper hand in chronic hand eczema
Excellent long-term data for TYK2 inhibitor ESK-001 in psoriasis
ICONIC-LEAD in plaque psoriasis
A ‘TYK’ above placebo: ICP-488 in plaque psoriasis
TYK2 inhibitor D-2570 safe and effective in psoriasis
Flexing upadacitinib dose adjustment for AD and itch relief
ROCKET ignites interest in rocatinlimab
Reduced biopsy rate and improved malignancy rate with high-end imaging tool
Cutaneous immune-related AEs may predict toxicities in ICI-treated patients
Clinical patterns and outcomes in hypopigmented mycosis fungoides
Bempikibart shows its potential for hair regrowth in alopecia areata
Ivarmacitinib stimulates hair regrowth in severe alopecia areata
Baricitinib regrows hair in adolescents with alopecia areata
Briquilimab breaks walls in chronic spontaneous urticaria
New anti-IL-23p19 inscribes its name on the plaque
How to recognise and manage Schnitzler syndrome in clinical practice
Expanding treatment armamentarium for actinic keratosis and Bowen’s disease
VEXAS syndrome and its cutaneous manifestations
Management of atopic dermatitis in children in 2025
New horizon for classifying and managing vascular anomalies
How to deal with misinformation in the medical world
AAD 2025 Highlights Podcast
Letter from the Editor
3-Year results highlight durable effects of IL-13 inhibitor in AD
IL-22RA1 inhibition shows potential in atopic dermatitis
Lifelong psychosocial burden linked to early-onset atopic dermatitis
Second-generation selective PDE4 inhibitor shows promise in AD
Prurigo nodularis: long-term treatment decreases relapse events
JAK1 inhibitor shows promising long-term efficacy in PN
Deucravacitinib treatment in lichen planopilaris
Delgocitinib cream outperforms oral alitretinoin in chronic hand eczema
Atopic hand eczema: similar treatment success for dupilumab and topical delgocitinib
Targeting IL-17A offers a promising treatment perspective in hidradenitis suppurativa
Bimekizumab shows sustained 2-year efficacy in hidradenitis suppurativa
Familial hidradenitis suppurativa tied to metabolic disease
Imsidolimab potential future therapeutic avenue for generalised pustular psoriasis
A new era of care: Artificial intelligence in psoriasis
Deuruxolitinib significantly improves hair satisfaction in AA
Topical pan-JAK inhibitor mitigates inflammatory biomarkers in frontal fibrosing alopecia
Vitiligo: Prolonged facial re-pigmentation maintained with continued ruxolitinib cream
Anti-KIT antibody: the next frontier in CSU treatment?
New targets identified for acute and chronic wound healing
PsoBest registry: Biologics dominate treatment for moderate-to-severe psoriasis
Semaglutide improves outcomes for patients with obesity and HS
Advanced BCC: histological subtype and time to complete response may predict tumour recurrence
Neoadjuvant nivolumab/ipilimumab improves DMFS in stage III resectable melanoma
New neoadjuvant combinations in stage III melanoma
Long-term benefit of nivolumab, ipilimumab, and pembrolizumab: 10-year survival data
Early treatment with ambrisentan might prevent PAH development in patients with SSc
Dermatomyositis: Triple therapy with tacrolimus beats cyclosporin regimen
Highly significant event-free survival benefit with neoadjuvant nivolumab/ipilimumab in stage III melanoma
Neoadjuvant intralesional daromun improves relapse-free survival in stage III melanoma
Intratumoural tilsotolimod shows no benefit for advanced refractory melanoma
How close are we to personalised medicine in psoriatic arthritis?
Genetic and immunological advances in risk assessment and treatment of psoriatic diseases
Using advances in the genetics of psoriatic disease to better predict treatment response
Depression complicates the management of psoriatic disease
The unfavourable role of obesity in psoriatic disease
Managing obesity and fibromyalgia in psoriatic disease
Multiple novel oral agents show promise in psoriasis
Biologics for psoriasis: towards oral therapies and less frequent dosing
Advances in psoriasis treatment: topical therapies show promising results
Improving outcomes in pregnancy and psoriatic disease
Towards prevention of psoriatic arthritis in patients with psoriasis
Diagnosing generalised pustular psoriasis
Itch and pain are major components of psoriatic disease and require management
Can diet help with the management of psoriasis?
Biologics in psoriatic arthritis: where we are and where we are headed
Letter from the Editor
The management of lymphoedema in 2024
Diagnosing skin disorders in patients with skin of colour
What’s new in clinical dermatology?
Safety and efficacy of a therapeutic HPV vaccine in high-grade anal intraepithelial neoplasia
Artificial intelligence in dermatology: current applications and future horizons
Digital dermatology in the Dutch treatment landscape
Improving risk classification in cutaneous squamous cell carcinoma
Skin cancer in transplant patients: practical challenges
Ins and outs of tumour-infiltrating lymphocytes therapy in metastatic melanoma
Understanding bullous pemphigoid: a rare skin condition
Advancements in gene therapy for epidermolysis bullosa
Interview: State-of-the-art dermatology care in the Netherlands: “The future of dermatology is bright”
Letter from the Editor
Children with atopic dermatitis may be smaller and heavier than healthy children
JAK inhibitors have similar incidence rates of long-term adverse events as traditional immunomodulators
Baricitinib maintains regrowth of hair, eyebrows, and eyelashes over 3 years
GUIDE demonstrates: Hit hard and early in psoriasis
Hidradenitis suppurativa treatment with secukinumab linked to low immunogenicity
HS: Targeting IL-1 pathway potential option after anti-TNF failure
BTK signalling as a novel target in hidradenitis suppurativa treatment
Topical ruxolitinib shows promise in milder stages of hidradenitis suppurativa
Robust long-term efficacy of bimekizumab in psoriasis
Benefit and safety of TYK2 inhibitor ESK-001 for psoriasis in phase 2
Durable skin clearance by IL-23 blockers due to reduction of resident memory T cells
Amlitelimab leads to a high response 28 weeks after treatment discontinuation
Delgocitinib cream: A promising treatment option for chronic hand eczema
Upadacitinib: A novel treatment option for vitiligo
JAK1 inhibitor meets primary endpoint in prurigo nodularis
Botanical drug solution leads to sustained hair regrowth in paediatric alopecia
SGLT2 inhibition: A possible mode-of-action for inflammatory skin diseases?
Promising first results of novel topical treatment for congenital ichthyosis
Ritlecitinib also effective in patients with total hair loss
Meet the Trialist: Dr Andrew Blauvelt on the KNOCKOUT Trial
Interview: Medicare’s first drug price negotiations: concerning?
Tapinarof on course to become a new topical treatment in AD
Upadacitinib provides sustained skin clearance in adolescents and adults with AD
Sustained deep clinical and itch responses with novel IL-13 inhibitor
IL-13 inhibitor shows potential in atopic dermatitis
Encouraging results for amlitelimab in atopic dermatitis
Chronic hand eczema: patients share similar molecular signatures regardless of AD status
Severe hand eczema: dupilumab could be a future treatment
Dual IL-17 blockade yields efficacy on joints and skin
High-dose subcutaneous spesolimab prevents GPP flares up to week 48
Drug survival of guselkumab and risankizumab seems superior to other biologics
IL-23 blockers may lower the risk of developing inflammatory and psoriatic arthritis
First-in-class oral IL-23 inhibitor safe and effective for moderate-to-severe plaque psoriasis
Skin tape stripping allows a novel precision medicine approach in HS
Nanobodies: A novel way to treat HS
Anti-IL17 blockade leads to maintained pain reduction in patients with HS
JAK1 inhibition: a promising forthcoming treatment option in vitiligo
Vitiligo: Continuation of topical ruxolitinib successful in many initial non-responders
JAK3/TEC inhibition achieves clinically meaningful responses in AA
Alopecia areata: remarkable regrowth rates with deuruxolitinib
Botanical drug solution improves hair regrowth in children and adolescents with AA
Nemolizumab shows high success rates in prurigo nodularis
Remibrutinib reduces itch, sleep problems, and activity impairment in patients with CSU
Innovative wound gel reduces frequency of painful dressing changes in epidermolysis bullosa
Women with psoriasis face increased adverse effects with systemic therapy
Improved AI tool shows high sensitivity rates in skin cancer detection
Dermoscopy training combined with AI significantly improves skin cancer detection
Topical gene therapy for recessive dystrophic epidermolysis bullosa
Strategies for Early Psoriatic Arthritis Recognition in Psoriasis Patients: GRAPPA Survey Findings
Alopecia areata: Ritlecitinib generates substantial re-growth of scalp hair
Promising results in AD treatment with an OX40 ligand inhibitor
Differential effect of biologics for psoriasis on the risk of developing arthritis
Innovative wound gel significantly reduces daily dressing changes in epidermolysis bullosa
Generalised pustular psoriasis: IL-36 inhibits new flares up to week 48
Patience is rewarded in initial non-responders to topical ruxolitinib with vitiligo
Women with psoriasis face increased adverse effects with systemic therapy
Dupilumab – a future option for severe hand eczema?
Vitiligo: Oral JAK1 inhibitor induces increasing repigmentation over time
IL-23p19 inhibitors have a superior drug survival compared with other biologics
Skin tape stripping: Can it pave the way for early diagnosis in HS?
Topical tapinarof – a rising star in atopic dermatitis
Botanical drug solution improves hair regrowth in children and adolescents with AA
Anti-IL17 blockade leads to maintained pain reduction in patients with HS
Nemolizumab shows high success rates in prurigo nodularis
JAK inhibitor provides sustained skin clearance in adolescents and adults with AD
Nanobody sonelokimab shows efficacy in hidradenitis suppurativa
Letter from the Editor
Rocatinlimab delivers efficacy and safety in atopic dermatitis
Head-to-head: paraffin- versus ceramide-based moisturiser for paediatric AD
JAK inhibitors for AD in the real world
Novel JAK1 inhibitor for patients with atopic dermatitis
Can lebrikizumab maintain response rates in atopic dermatitis?
Most patients with AD on dupilumab stick with this drug long-term
Botulinum toxin A might provide efficacious treatment option for nail psoriasis
POETYK PSO-1 and 2: Long-term efficacy results of deucravacitinib in plaque psoriasis
Encouraging results for first oral IL-23 receptor antagonist in plaque psoriasis
Subcutaneous spesolimab for GPP flare prevention
Knocking out psoriasis with high-dose risankizumab?
Deucravacitinib versus other systemic therapies in Asian patients with psoriasis
Patients with AA report high long-term regrowth rates with baricitinib
Can ritlecitinib deliver long-term efficacy in alopecia areata?
TikTok videos on hair disorders lack reliability
Spesolimab appears successful in hidradenitis suppurativa
Promising results for paroxetine in rosacea
Novel PPARγ modulator reduces acne manifestations
Microencapsulated benzoyl peroxide shifts skin microbiome in rosacea
OLYMPIA 2: Positive results for nemolizumab in prurigo nodularis
PRFM or PRP therapy for trophic ulcers due to leprosy?
Large teledermatology project in a remote island in Eastern Indonesia
Can AI-driven teledermatology increase access to healthcare in rural African settings?
Oleogel-S10 shows long-term efficacy and safety in dystrophic epidermolysis bullosa
Picosecond alexandrite laser safe and effective in benign pigmentary disorders
Gentamicin improves symptoms in paediatric Nagashima-type palmoplantar keratosis
Clinics on wheels – Bringing healthcare to patients in underserved communities
Biologics in psoriasis: can they prevent joint involvement?
JAK inhibitor deuruxolitinib shows encouraging hair re-growth in alopecia areata
Biomarkers predicting response of different CSU treatments in children
Izokibep shows remarkably high grades of clinical response in HS
Bimekizumab could be the new up-and-comer for HS treatment
Switching to risankizumab successful in IL-17 inhibitor non-responders
Novel, selective TYK2 inhibitor shows promise for psoriasis
As-needed ruxolitinib shows successful long-term symptom control in AD
Dupilumab: a viable option for atopic hand and foot eczema
Topical roflumilast beneficial in atopic dermatitis
IL-22 receptor blocker reduces itch and skin lesions in AD
Delgocitinib shows promise as topical therapy for chronic hand eczema
Vitiligo patients maintain re-pigmentation after ruxolitinib cream withdrawal
Nemolizumab decreases lesions and itch in prurigo nodularis
Lichen planus: a future indication for baricitinib?
Letter from the Editor
Letter from the Editor
Eligibility and selection of JAK inhibitors for constitutional eczema
The rise of JAK inhibitors for alopecia areata
Obesity and the skin: state of affairs
The role of surgeons in stage I–II melanoma
Skin diseases and nutrition
Melanoma: Surveillance and follow-up
When to screen for anal intraepithelial neoplasia?
The importance of anti-microbial proteins in the skin
Scabies: Therapy failure and tips for the clinic
Life-threatening skin infections
OCT non-inferior to biopsy in basal cell carcinoma
Top 14 Medical Innovations for 2022
Letter from the Editor
High rate of non- or partial responders jeopardises therapeutic success in HS
Genital psoriasis: high prevalence, often underdiagnosed
Decreased overall survival in melanoma patients with low vitamin D
High potential for secukinumab as next biologic treatment for HS
Hidradenitis suppurativa: TYK2/JAK1 inhibitor shows promise
Dupilumab leads to clinically relevant improvements in signs and symptoms of prurigo nodularis
Nalbuphine: aspiring to become another treatment for prurigo nodularis?
Notalgia paresthetica: may κ-opioid receptor agonists be a long-awaited effective therapy?
Enhancing re-pigmentation rates with topical ruxolitinib in all body areas
Markedly lower skin cancer risk in vitiligo patients
Myths regarding “health benefit” of suntan prevail in majority of population
Fern extract reverses severe actinic keratosis lesions
Novel oral psoriasis drug maintains efficacy over 2 years
A3 adenosine receptor agonist showed modest efficacy but excellent tolerability
Selective IL-23 inhibitor achieves long-term disease control in many patients with active PsA
AI machine learning algorithm useful in early detection of PsA
Long-term improvement in alopecia areata with ritlecitinib therapy
Topical gel plus finasteride beneficial for patients with androgenetic alopecia
Deuruxolitinib achieves hair regrowth, even in patients with severe alopecia areata
Baricitinib possible therapeutic option for children with AD
Amlitelimab therapy leads to sustained decrease of IL-22 in AD patients
IL-13 inhibition with lebrikizumab shows high maintenance rates in AD
Does 8 weeks of emollients use prevent AD in high-risk infants?
Roflumilast foam led to high response rates in seborrheic dermatitis
Letter from the Editor
Therapies for atopic dermatitis: still moving forward
Children with AD: high risk of bacterial infections in carriers of a filaggrin gene variant
Men on biologics report fewer adverse events than women
Conceptual framework of adverse drug reactions may improve treatment of patients with IMIDs
No adverse pregnancy outcomes in patients exposed to baricitinib
Systemic treatment for psoriasis: what is on the horizon?
Topical therapy in psoriasis: an important partner in combination therapy
GPP flares: pronounced undertreatment is common
All patients with GPP benefit from IL-36 inhibitor therapy
IL-17A/F inhibitor bimekizumab shows higher response and maintenance rates compared with secukinumab
Greater PASI reductions lead to less impairment in social and sexual life
Paediatric psoriasis: ixekizumab beneficial in difficult-to-treat areas
Psoriasis patients see great benefit in achieving complete skin clearance
Predilection sites for skin signs of vitiligo disease activity determined
IHS4 better suited as an outcome measure in HS trials?
New treatments for HS: IL-17 inhibitors next in practice?
Alopecia areata: light at the end of the tunnel
Alopecia areata pathogenesis: known genetic background, unknown environmental triggers
Psoriasis treatment: no elevation of MACE and VTE on deucravacitinib
Comorbid anxiety and depression may benefit from psoriasis treatment with certolizumab
Dose tapering in psoriasis is associated with a low relapse rate
Adjunctive reflective confocal microscopy can curb unnecessary excision for suspected melanoma
Green tea ingredient shows promise for preventing severe radiation dermatitis
Inpatient dermatologic therapy is linked to lower mortality and readmission rates
AD treatment during the pandemic: dupilumab does not raise COVID-19 infection risk
Letter from the Editor
Upadacitinib: Fast and more pronounced skin improvement in AD patients
Dermatology diseases need the highest doses of biologics
JAK inhibitors in AD: Setting the efficacy bar even higher
Lebrikizumab treatment leads to encouraging outcomes in multiple traits of AD
Novel IL-4/IL-13 blocker shows high efficacy with only modest conjunctivitis signal
New insights into psoriasis comorbidity
Long-term psoriasis treatment with bimekizumab results in maintained efficacy
Novel developments in topical psoriasis therapy
Add-on apremilast may improve recalcitrant dermatomyositis
Could dupilumab put an end to the therapeutic draught in prurigo nodularis?
Fungal skin infections in children: A diagnosis to keep in mind
Innovative gel speeds up clearance of molluscum contagiosum lesions
JAK inhibition offers promising treatment prospects for uncommon dermatoses
JAK inhibitors may offer a new horizon in the treatment of sarcoidosis
Light at the end of the tunnel for vitiligo therapy
JAK inhibitors: A risk assessment
Monitoring is key during JAK inhibitor therapy
Intestinal microbe-preparation: Modest activity but safe for mild psoriasis
Alopecia areata: 1-year baricitinib treatment increases success
New anticholinergic preparation is effective and tolerable in hyperhidrosis
Is melanoma screening by primary care practitioners linked with overdiagnosis?
Topical ruxolitinib continues to show promise for vitiligo
Arthritis drug beats placebo for treating severe alopecia areata
Dermatologists may be unaware of scalp cooling for chemo-induced hair loss
Melanoma-secreted amyloid beta likely curbs neuroinflammation, promotes brain metastases
Merkel cell cancers recur more often than other skin cancers, usually within three years
Race, socioeconomic status tied to melanoma survival
Letter from the Editor
Potential biomarker discovered for treatment response to ustekinumab
TNF inhibitor for immune-mediated inflammatory disease doubles the risk of paradoxical psoriasis
Secukinumab also tolerable in paediatric psoriasis patients
High treatment success with ixekizumab in patients with psoriasis and diabetes
The Yin and Yang of opposing vectors: an explanation for side effects of biologics
Explaining arthropathy development through IL-4 and IL-13 blockade
DLQI scores underestimated during lockdowns?
TNF blockers likely beneficial for psoriatic patients with COVID-19
Patients on immunomodulators need 2 COVID-19 vaccinations before seroconversion
IL-36 gene expression in GPP lesions reduced by spesolimab
Inhibition of heat shock protein: A novel way to treat psoriasis?
Guselkumab shows highest drug survival among systemic treatments
Risankizumab superior to ustekinumab in skin histopathology scores
Tapering biologics: No alarming signs of increased anti-drug antibodies
Intermediate monocytes are possible predictors of response to secukinumab
Gut microbiota of psoriasis patients: less diverse and reduced functionality
Psoriasis associated with a higher cancer risk
Comorbidity and clinical features of psoriasis vary according to HLA-C*06:02 status
Psoriasis patients with cardiovascular comorbidity characterised by high systemic inflammation
HLA-C*06:02-positive patients on ustekinumab show higher drug survival in a real-world scenario
Selective IL-23 inhibition normalises gene expression in active PsA
Protective factors identified against anti-drug antibody formation to adalimumab in psoriasis
Dermatologists and psoriasis patients call for specialized care to prevent heart disease
Radiomic signature may predict survival in pembrolizumab-treated advanced melanoma
Oral JAK inhibitor continues to show promise for alopecia areata
One week enough to clear pustular psoriasis in half of patients after experimental infusion
Experimental cream improves plaque psoriasis but can spark local side effects, headaches
An unusual case of E. coli cellulitis in an immunocompetent patient
Psoriasis tied to small increase in risk of venous thromboembolism, peripheral vascular disease
Autologous serum therapy benefits chronic spontaneous urticaria
Comparing routes of administration of methotrexate in psoriasis patients
Expanding the toolbox: what is new in melanoma detection?
Equity in dermatology: Skin Care For All
Challenges in diagnosis and treatment of leprosy in Brazil
A PASSION to provide dermatological care in LMICs
Paediatric dermatology in Tunisia: common diagnoses
Registry of vitiligo patients aims to break the stigma
Ceramides and their role in skincare
10% thioglycolic acid gel peels: a safe and efficient option for pigmented purpuric dermatosis
Benefits of microneedling with platelet-rich plasma for acne scars
Dupilumab for atopic dermatitis linked with milder COVID-19 symptoms
Targeting OX40 in the treatment of atopic dermatitis meets expectations
Superior EASI scores after switch from dupilumab to upadacitinib
CSU: Novel agent targeting Bruton’s tyrosine kinase leads to disease control
Novel JAK3/TEC blocker leads to maintained re-pigmentation in vitiligo
TYK2 inhibitor deucravacitinib shows impressive long-term response in psoriasis
Letter from the Editor
Tapinarof cream for psoriasis leads to high clearance rates and remittive effect
CSU: Ligelizumab likely safe and effective for adolescents
Long-term disease control in AD could be in reach with anti-OX40 antibody KHK4083
Topical JAK1/JAK2 inhibitor effective in vitiligo
Abrocitinib demonstrates fast itch control and skin clearance in atopic dermatitis
AD patients with stable response fare well with a monthly dose of tralokinumab
Damaged skin as a possible transmission route for SARS-CoV-2
Upadacitinib beats dupilumab in different body regions
Efficacious 2-year AD control with IL-13 inhibitor tralokinumab
Ruxolitinib cream: a safe treatment for elderly AD patients
Novel and upcoming targeted AD treatment
Existing and upcoming small molecules in psoriasis
Treating psoriasis during pregnancies
A patient-related approach to freedom of disease
Ixekizumab superior to secukinumab in real-world psoriasis study
Nail psoriasis: An important target to be treated
Grand debate: Is psoriasis a systemic or skin-only disease?
JAK1/2: A promising novel treatment target in alopecia areata
Alopecia areata: encouraging response rates with JAK3/TEC inhibition
Opioid receptor agonist difelikefalin disappoints in AD
Supplemental patch testing often needed to identify allergens in contact dermatitis
EADV 2021 Highlights Podcast
COVID toes and seasonal chilblains share similar immune responses
Potential first-in-class drug shows disease-modifying impact in atopic dermatitis
Do oral corticosteroids drive fracture risk in atopic eczema?
Live varicella-zoster vaccine safe, effective with TNF inhibitors
Could steroid treatment speed recovery from infliximab-induced liver injury?
Unresolved needs for patients with PsA despite growing therapeutic options
PsoBarrier EU: Large survey evaluating quality of care in Europe
Bridging the gap between patients and access to psoriasis specialists
Psoriasis and PsA in transgender adults on hormone therapy
Psoriasis: New disease severity classification
Immune checkpoint inhibitors in patients with pre-existing psoriasis
Psoriasis registries yield important data about COVID-19
COVID-19 affects patients and care
Vaccination feasible in people with psoriatic disease
Low COVID-19 risk for patients with psoriasis on biologic treatment
Psoriasis: Disrupted gut-skin axis
Psoriasis associated with increased duodenum inflammation
Whole-exome sequencing to study the underlying pathogenesis of psoriasis
Pan-European guidelines for the treatment of psoriasis and comorbid conditions
Psoriatic arthritis: Guidelines and best practice
Patients with PsA have a higher cardiovascular risk
Potential role of inflammation in cardiovascular comorbidity
Psoriasis: New treatments and current pipeline
Rapid pustule and skin clearance with IL-36 receptor inhibitor spesolimab
Selective TYK2 inhibitor effective in moderate-to-severe plaque psoriasis
Letter from the Editor
Severe atopic dermatitis tied to depressive symptoms, internalizing behaviors in children
Adoptive cell therapy less effective in pretreated metastatic melanoma
Upadacitinib bests dupilumab for adults with moderate-severe atopic dermatitis
Hair shedding related to COVID-19 doesn’t last long
Certain biologics may boost serious infection risk in patients with psoriasis
Blistering eruptions, including bullous pemphigoid, seen after COVID vaccine
Patch tests ‘essential’ in patients who develop facial dermatitis from face masks
Allergies: an underrated factor in alopecia pathogenesis
Psoriasis and hidradenitis suppurativa during COVID-19: keep calm and carry on
Psoriasis: The treatment armamentarium continues to grow
COVID-19 in children – cutaneous involvement is common
Psoriasis management in times of COVID-19: the knowledge is growing steadily
Cutaneous reactions after COVID-19 vaccination: an update
Sunless tanning and other developments in sun protection
Comorbidity does not influence crisaborole efficacy in atopic dermatitis
Comorbidity is common in adult and paediatric atopic dermatitis patients
Lower burden of high-risk atherosclerotic plaques in psoriasis patients treated with biologics
Botulinum toxin A: a contradictory role in hair loss
New therapeutic options add value to current acne treatment
Significant improvements in the system armamentarium for AD treatment
Nicotinamide and probiotics can support acne therapy
Convincingly low levels of infections with long-term tildrakizumab
No increased risk of infection with long-term dupilumab for atopic dermatitis
Topical pan-JAK inhibitor cream safe and efficacious in atopic dermatitis
Atopic dermatitis in children has a severe impact on their families
IL-17 inhibitor effective in axial manifestations of psoriatic arthritis
Platelet-rich plasma in androgenetic alopecia – hype or hope?
‘Maskne’ – How can it be managed?
Meaningful amelioration of quality of life in paediatric AD patients on dupilumab
Small molecule effective in moderate-to-severe psoriasis
Bruton’s tyrosine kinase inhibition promising for pemphigus vulgaris
Bimekizumab superior to secukinumab in psoriasis
Etrasimod – a new mode of action for treatment of atopic dermatitis
Women at higher risk for dermatologic side effects during immunotherapy
Novel easy-to-use foam formulation clears scalp psoriasis in one-third of patients
Anti-cholinergic gel demonstrates superior long-term tolerability and efficacy in axillary hyperhidrosis
Baricitinib shows long-term effectiveness against moderate to severe atopic dermatitis
Letter from the Editor
CO2 laser monotherapy of questionable efficacy in vulvar lichen sclerosus
Rituximab bests mycophenolate mofetil as one-year treatment for pemphigus vulgaris
New psoriasis injection bests secukinumab, adalimumab in separate tests
Wildfire air pollution linked to jump in atopic dermatitis and itch dermatology visits
Switch from adalimumab to its biosimilar not tied to drug retention in psoriasis patients
Surveillance, education may help to catch melanomas earlier
Novel drug first to improve outcome of metastatic uveal melanoma
Survival after Mohs surgery likely better at academic, high-volume facilities
Dermatologists can help identify, predict immune-checkpoint inhibitor toxicity
Psoriasis associated with liver diseases beyond NAFLD
Pfizer’s atopic dermatitis drug bests dupilumab, but only at higher dose
Risankizumab long-term risk-benefit profile for moderate to severe psoriasis
Pediatric atopic dermatitis tied to school, work absenteeism
ctDNA levels promising for tracking melanoma treatment progress, predicting outcomes
Tirbanibulin ointment clears actinic keratosis lesions in half of recipients within two months
Personal neoantigen vaccine prompts lasting response in melanoma patients
Severe atopic eczema tied to higher risk of premature death
Clinicians recommend hair pull test of up to two hairs for all textures
Dermatologists call for regulation of direct-to-consumer skin-lightening products
Metastatic-melanoma immunotherapy may be tied to increase in second cancers
Risky sexual behaviour and STIs on the rise despite the pandemic
Real-world data on brodalumab affirms efficacy and fast onset of action
Bimekizumab in psoriasis: Up-and-coming
Heightened risk for psychiatric comorbidities in hidradenitis suppurativa patients
Meaningful sleep improvement with IL-13 inhibition
Preventing foot odour with zinc oxide coated socks
Baricitinib in AD: Efficacy paired with consistent long-term results
Bacterial resistance in skin infections – a challenging threat
Chronic inducible urticaria can require some detective work
Borreliosis: A multifaceted disease
JAK inhibitors in AA: re-establishing the immune privilege of hair follicles
Chronic spontaneous urticaria: hives, wheals & biomarkers
Scabies – A global health challenge
Ligelizumab for chronic spontaneous urticaria: a new star on the horizon
JAK inhibitors in vitiligo
JAK1 inhibition successful in hidradenitis suppurativa
Topical JAK inhibition: a novel treatment option for patients with mild-to-moderate AD
Biologic psoriasis treatment and COVID-19 risk: Contradictory results
Much to be learned about COVID-19 and the skin
Selective IL-23 blocker shows potential in psoriasis treatment
Promising results with nanobody treatment in psoriasis
Light at the end of the tunnel for chronic hand eczema
Epidermolysis bullosa: Novel wound treatment on the horizon
Efficacious non-steroidal topical for psoriasis
Oral JAK 1 inhibitor leads to fast itch relieve and remarkable skin clearance in AD
Effects IL-13 blocker improves with longer treatment duration
Mohs surgery may not boost survival over standard excision of melanomas on trunk, extremities
Risankizumab improves patient-reported outcomes in moderate to severe psoriasis
Cantharidin-based drug-device combination likely safe, effective for molluscum contagiosum
Narrowband UVB for vitiligo linked to lower fracture risk
Higher risk of severe cardiovascular events seen in months after starting ustekinumab therapy
Improvement of coronary-artery-plaque lipid-rich necrotic core seen with biologic therapy of psoriasis
Five-year follow-up confirms drug combo lowers odds of melanoma recurrence
Letter from the Editor
Selective IL-23 blocker safe in elderly psoriasis patients
Spironolactone safe for androgenetic alopecia in cancer survivors
Baricitinib beneficial in head and neck AD
Continuous terbinafine most effective for toenail onychomycosis
ECLIPSE trial: skin clearance independent of PsA status at baseline
Intranasal kappa-opioid agonist effective for intractable pruritus
HS patients carry higher risk for systemic lupus erythematosus
Biologics in HS – a growing armamentarium
How to manage cutaneous side effects of immunotherapy
Cannabinoids: a future role in dermatology?
Psoriasis therapy for children and pregnancies
Biologic psoriasis treatment to lower cardiovascular risk?
A new topical PDE-4 inhibitor effective in psoriasis
IL-17A and IL-17F blockade remarkably effective in psoriasis
Good response and pruritus reduction in AD with novel selective JAK1 inhibitor
Novel IL-23 blocker risankizumab highly effective and tolerable in psoriasis
IL-13 blocker tralokinumab effective in AD
Tape stripping – a painless way to distinguish AD and psoriasis?
IL-4/IL-13 blocker dupilumab effective in children with severe AD
Pembrolizumab leads to higher toxicity risk in obese melanoma patients
Can gene expression help to pick the right biologic to treat psoriasis in cancer patients?
Omalizumab for cancer-induced dermatoses
Better compliance in AD skin care with novel emollient stick
IL-17A blocker effective in paediatric psoriasis patients
Small molecules: interesting novel treatment options in AD
Rituximab beats mycophenolate mofetil in pemphigus vulgaris
IL-1⍺ blockade: a new treatment option in AD
IL-4/IL-13 blockade leads to rapid itch reduction in adolescents
Novel JAK1/2 inhibitor shows remarkable efficacy in alopecia areata
Acne highly influenced by climate, pollutants, and unhealthy diet
JAK inhibition plus TCS lead to high clearance rates in AD
How to manage conjunctivitis in AD patients treated with a biologic
Biologics: increasingly used in paediatric dermatology
No cancer risk with long-term use of tacrolimus, a topical calcineurin inhibitor, in children with AD
Green light for a second JAK inhibitor in AD
Topical ruxolitinib effective in vitiligo
Above-the-neck melanoma more prone to metastases
Comorbidities more common in chronic urticaria, psoriasis, and AD
IL-17 blocker: effective and safe in patients with comorbidities
Reduced sleep quality in dermatoses influenced by itch and pain
Systemic photoprotection: a valuable addition to topical sun protection
ESPRIT registry: sharp decline in mortality in patients treated with a TNF blocker
Anxiety and depression are common in families of AD infants
D-Dimer as future biomarker in CSU management?
Relationship psoriasis and NAFLD: new data on the hepato-dermal axis
Novel selective IL-23 blocker equally effective in patients with metabolic syndrome
Selective IL-23 blocker crushes fumaric acids in all assessed efficacy endpoints
Certolizumab pegol efficacious for head and neck psoriasis
New guidance on rosacea therapy according to phenotype
Ligelizumab for CSU: symptom control and high response rates in re-treatment
The underestimated effect of visible light
No hint of teratogenicity through ixekizumab
Letter from the Editor
Statin use elevates risk of eczema and atopic dermatitis
Will malignant melanoma become a curable disease?
Cutaneous adverse events due to EGFR inhibitors
Keloids: a faulty switch in wound healing?
Letter from the Editor
Insights into pathogenesis of AD define novel therapeutic targets
Novel treatment options for many dermatologic indications
Various guidelines with much overlap
Management strategies for drug-induced mucositis
Treating keloids with injections
Long awaited oral therapy for moderate-to-severe AD
Choosing the right biologic in psoriasis
Novel treatment options in alopecia areata and vitiligo
Antibiotics in hidradenitis suppurativa
Treating keloids with lasers
New targets and biologics for cutaneous lupus erythematosus
Novel selective IL-23 blocker highly effective over 2 years
Surgical management of melanoma
What the future of keloid treatment could hold
Biologicals beyond TNF blockade
Novel lupus classification will aid future research
Skin toxicity of immune checkpoint inhibitors
Combinations are hot in AD treatment
Registries – an important research tool in biologics
Advances in target-oriented therapy: psoriatic arthritis
Favourable safety profile of long-term use of ixekizumab
Brodalumab onset of action is significantly faster than ustekinumab: Results from the phase 3 AMAGINE-2 and -3 studies
Adalimumab vs adalimumab + methotrexate in psoriasis: First-year results on effectiveness, drug survival, safety, and immunogenicity
Understanding genetics to unravel psoriasis and atopic dermatitis pathogenesis
Granulomatous rosacea: exploratory histological markers
Ustekinumab for the treatment of moderate-to-severe plaque psoriasis in paediatric patients
Live imaging of cutaneous immune responses
Results from the ECLIPSE trial: does blocking IL-23 have better long-term outcomes in psoriasis?
Fumarates and vitamin A derivatives advance and latest insights in non-biologic systemic therapeutic agents in psoriasis and atopic dermatitis
ABP501 biosimilar for adalimumab: What you need to know
Switching infliximab biosimilars safe in treating chronic plaque psoriasis
Sustained and complete responses from the phase 3 AMAGINE-2 and -3 studies
Certolizumab: Long-term safety and efficacy results for psoriasis-related nail disease
Reduction in coronary artery disease in psoriasis patients treated with biologic therapies, possible implications for atopic dermatitis
Atopic dermatitis and psoriasis: on a spectrum?
Letter from the Editor
Treatment goals in psoriasis
Small molecules, apremilast, and TYK2
Letter from the Editor
Interview with AAD president Prof. George J. Hruza
Secukinumab maintains improvements in psoriasis through 5 years of treatment
Bermekimab – a future treatment for atopic dermatitis?
JAK1/2 inhibitor effective in alopecia areata
Oral antibiotics for acne treatment
New and emerging atopic dermatitis therapies
Novel anti-IgE drug enables durable urticaria control
JAK inhibitors: a new therapeutic tool for dermatologists
Plaque psoriasis – Efficacy of guselkumab
Dual IL-17A and IL-17F blocker leads to unprecedented response rates in psoriasis
Pemphigus patients prone to osteoporosis
JAK inhibitors: a pathogenesis-directed therapy for alopecia areata
Thicker AK lesions benefit from laser pretreatment with high channel density
Tralokinumab improves eczema and reduces staphylococcus aureus colonisation in AD
New standardised cantharidin product against molluscum contagiosum efficacious in two phase 3 trials
Bruton’s tyrosine kinase inhibitor highly effective in pemphigus vulgaris
Intralesional 5-fluorouracil induced high clearance rates in cutaneous squamous cell carcinoma
Serlopitant reduces pruritus associated with psoriasis
Hair Loss: No Reason for Therapeutic Nihilism
Vitiligo in children
Can JAK inhibitors close the current therapeutic gap in AD?
Psoriasis and Biologics: The Beat Goes On
Should we use more hormonal therapy?
Surgical treatment for selected vitiligo cases
JAK-inhibitors: an emerging treatment option for vitiligo
Food triggers eczema – an imperturbable belief of patients
Letter from The Editor
Better gastrointestinal tolerability with biologics than the conventional therapy
Living in the golden age of psoriasis and atopic dermatitis therapies
Improvement in impact of genital psoriasis on sexual activity with use of ixekizumab
Intralesional cryosurgery and itching in psoriasis
Winter effect and preventing scarring
AD sleep disturbance, antihistamines and osteoporosis
Melanoma incidence continues to rise in Europe
Oral therapeutics, supersaturation and excimer laser
A glimpse into the future
Lesions in paediatric patients and possible correlation with coffee drinking
IL-17C inhibition in AD and new oral treatments
New agents and combination therapy
Restrictive antibiotic use and novel tetracycline
New topical and systematic treatments
Dual JAK/SYK inhibitor and anti-IL-33 blockade
Psoriasis: Selective IL-23 blocker, analysis of VOYAGE-2, dual IL-17 inhibitor and ustekinumab
CNNs and targeted combination therapy
Hyperhidrosis: Soft molecule and anticholinergic towelettes
Psoriasis management online?
IL-4/IL-13 inhibition
Behcet’s syndrome and hidradenitis suppurativa
Letter from the Editor
Interview with Prof. Martin Röcken
Letter from the Editor
Letter from the Editor
Endocrinology
Therapeutic equivalence between denosumab and biosimilar Bmab-1000
DPP-4 is better target to lower migraine rates in patients with type 2 diabetes
Neoadjuvant chemoradiation does not improve surgical outcomes or survival in pancreatic cancer
Liraglutide achieves 5.8% reduction in BMI for children aged 6-12
FINE-HEART: Finerenone demonstrates benefits in patients with T2D
Dapagliflozin enhances kidney function and reduces albuminuria in low-renal-risk T2D patients
177Lu-DOTATATE significantly extends PFS in patients with GEP-NETs, regardless of grade or origin
Promising first results of mitazalimab in metastatic pancreatic ductal adenocarcinoma
No advantage of neoadjuvant radiochemotherapy over neoadjuvant chemotherapy in borderline resectable pancreatic cancer
NETTER-2: Practice-changing results for 177Lu-DOTATATE in GEP-NETs
Interview: Medicare’s first drug price negotiations: concerning?
Top 10 medical breakthroughs in 2023
Top 14 Medical Innovations for 2022
Head-to-head: Etoposide and irinotecan equally effective in neuroendocrine carcinoma
Dapagliflozin tied to reduction in new-onset diabetes in patients with CKD, heart failure
High-frequency spinal cord stimulation provides lasting relief of painful diabetic neuropathy
Dapagliflozin curbs albuminuria in CKD with or without diabetes
No benefit of adding axitinib to ocreotide acetate in non-pancreatic neuroendocrine tumours
Phase 2 abemaciclib trial in patients with advanced NETs
Ertugliflozin offers some kidney protection
DAPA-CKD trial shows extensive benefits of dapagliflozin
Empagliflozin significantly reduces CV and renal risk
Poor prognosis for T2D patients on loop diuretics in addition to SGLT2 inhibitor
Once daily oral treatment with glucokinase activator TTP399 reduced HbA1c in patients with type 1 diabetes
High risk of vascular dementia in patients with T2D
HbA1c reduction with GLP-1RA leads to lower risk of CV events in cardiovascular outcome trials
Diabetes still goes unnoticed, resulting in delayed diagnosis
Patients with RA have higher risk of developing diabetes
Once-weekly insulin is a promising treatment option
Non-invasive monitoring by measuring glycated albumin in tears
More exercise means less risk of all-cause mortality amongst T2D patients.
Intermittent fasting: consuming fewer calories but in a different way.
Spread through air spaces is prognostic in lung neuroendocrine tumours
Prognostic value of distant organ-specific metastases in newly diagnosed lung neuroendocrine tumours
Gastroenterology
Letter from the Editor
Antibody responses predict IBD onset 10 years before diagnosis
Therapeutic antibody clearance reliable predictor for endoscopic outcomes in CD
Higher neoplasia detection rate with virtual chromoendoscopy in real-world IBD study
Reducing the carbon footprint of IBD care
TL1A-LTB axis induces perianal fistulising disease-associated changes in CD
Emulsifier-restrictive diet effective in alleviating symptoms in CD
Could stem cell transplantation be a fruitful solution for refractory CD?
First IL-7 inhibitor for UC shows its potential
Novel TL1A inhibitor achieves high rates at stringent endpoints in UC
Positive results for TL1A inhibitor duvakitug in CD
Improving efficacy with longer mirikizumab treatment in CD
Long-term upadacitinib data reassuring for patients with UC
EFFICACI: Infliximab or vedolizumab after TNF failure in UC?
Latest data for subcutaneous guselkumab in CD and UC
Long-term use of etrasimod in UC safe and well-tolerated
Sustained efficacy and stable safety profile for risankizumab in UC
VEDOKIDS: Long-term outcomes of vedolizumab in paediatric IBD
PREdiCCT: Role of psychosocial factors in IBD flares unravelled
Kono-S or side-to-side anastomosis for resection in Crohn’s terminal ileitis?
Identifying patients at high risk for chronic pouchitis
ECCO consensus on diet and nutrition in IBD
ECCO Topical Review: pouch-related disorders
ECCO 2025 Highlights Podcast
Letter from the Editor
A paradigm shift in CD clinical practice
LOVE-CD: Vedolizumab yields better outcomes in early than in late CD
Moving towards the prevention of IBD
New insights into perianal fistulising CD pathogenesis may lead to new therapies
Risankizumab influences key pathogenic Th17 cells in CD
Meaningful corticosteroid-sparing effect of mirikizumab in UC
Extending ustekinumab dosing interval does not influence drug survival in IBD
CULTIVATE: Promising signal for etrasimod in Crohn’s disease
Tamuzimod delivers promising long-term data in UC
TL1A inhibitor tulisokibart shows potential in UC
Upadacitinib associated with normalisation of HRQoL in UC
Diagnostic accuracy of fluorescence confocal laser microscopy after EUS-TA
An accelerated treatment approach may save lives in pancreatic walled-off necrosis
Guar gum alleviates IBS-related constipation in a randomised controlled trial
How useful is colonoscopy for constipation in young women?
Tradipitant improves symptoms of motion sickness
Encouraging results for L-carnitine in metabolic dysfunction-associated steatotic liver disease
Exploring zibotentan plus dapagliflozin for cirrhosis
TACITO: Does faecal microbiota transplantation improve survival in mRCC?
Is faecal microbiota transplantation a viable option to treat primary C. difficile infections?
Cendakimab meets primary endpoints in eosinophilic oesophagitis
Neoadjuvant chemoradiation does not improve surgical outcomes or survival in pancreatic cancer
Adding lenvatinib plus pembrolizumab to TACE improves PFS in intermediate-stage HCC
Benefit of adjuvant atezolizumab/bevacizumab in HCC not maintained over time
Pre-operative chemoradiation does not improve survival in resectable gastric cancer
Final results of the IKF-AIO-Moonlight trial
Retifanlimab boosts survival in patients with anal cancer
NICHE-2 and NICHE-3 show high efficacy of short neoadjuvant immunotherapy in dMMR colon cancer
Organ-preserving regimens in rectal cancer
No benefit of high-dose vitamin D3 supplementation in mCRC
More highlights in Colorectal Cancer
AI facilitates early detection of hepatocellular carcinoma
177Lu-DOTATATE significantly extends PFS in patients with GEP-NETs, regardless of grade or origin
Durvalumab plus chemotherapy enhances 3-year survival in advanced biliary tract cancer
Promising first results of mitazalimab in metastatic pancreatic ductal adenocarcinoma
Post-operative MRD status more prognostic than TNM stage
CAPRI 2 GOIM trial navigates biomarker-driven therapy
Meta-analysis of triplet therapy in BRAFV600E-mutated mCRC
CheckMate 8HW: Nivolumab/ipilimumab in MSI-H/dMMR mCRC
Sequence effect for third-line treatment of mCRC
REGINA meets stage 1 endpoint in rectal cancer and moves to stage 2 with reduced dose regorafenib
High efficacy of pembrolizumab combined with standard therapy in patients with MSS/pMMR mCRC and high immune infiltrate
Prognostic value of ctDNA in stage III colon cancer
Neoadjuvant combined immunotherapy also effective in MSS/pMRR CRC
Neoadjuvant immunotherapy plus radiation effective in advanced MSI-H rectal cancer
Peri- or post-operative chemotherapy benefits patients with resectable CRCLM
MINOTAUR: Promising phase 1 data for lunresertib plus FOLFIRI
TRANSMET meets OS endpoint
No survival benefit of tumour debulking for patients with multi-organ metastatic CRC
Thermal ablation of small-size colorectal liver metastases is non-inferior to resection
Benefit of first-line nivolumab/ipilimumab in MSI-H/dMMR metastatic CRC
Neoadjuvant checkpoint blockade in MSI-H/dMMR CRC
CodeBreaK 300: Promising survival trends in KRAS G12C-mutated mCRC
FLOT outperforms CROSS in resectable oesophageal cancer
Nivolumab/ipilimumab combination outperforms TKIs in unresectable HCC
No advantage of neoadjuvant radiochemotherapy over neoadjuvant chemotherapy in borderline resectable pancreatic cancer
Letter from the Editor
Mepolizumab improves the histologic severity of eosinophilic oesophagitis
Budesonide demonstrates efficacy in eosinophilic oesophagitis
Dupilumab shows promising results in treating paediatric eosinophilic oesophagitis
Quality-of-life assessment in children with eosinophilic oesophagitis
Gut permeability and neuroinflammation linked in Parkinson’s disease
Promising data for cardiovascular outcomes of bariatric surgery in patients with obesity
Survodutide meets expectations in MASH
GALAXI 2 & 3: Guselkumab proves efficacy in Crohn’s disease
QUASAR maintenance study: Guselkumab effective and safe for UC
VEDOKIDS: Vedolizumab maintains remission in patients with paediatric IBD
ADMIRE-CD II: Darvadstrocel does not meet primary endpoint in complex Crohn’s perianal fistulas
PREEMPT CRC: Blood-based screening test for colorectal cancer shows promise
New cable-transmission capsule endoscopy shows high accuracy in detecting upper GI lesions
Superior OS with atezolizumab plus bevacizumab versus lenvatinib in unresectable HCC
Nutritional consultation boosts nutritional status in patients with alcohol-associated hepatitis
REGENERATE study: Obeticholic acid shows antifibrotic benefit in NASH
Acalculous cholecystitis as a risk factor for gallbladder perforation: insights from a 10-year retrospective study
STARS: Apraglutide shows efficacy in short bowel syndrome with intestinal failure
COX-2 inhibitors show promise in reducing severity of acute pancreatitis
Hormone-containing therapies may increase the risk of IBS and functional dyspepsia
Letter from the Editor
VIVID-1: Mirikizumab meets expectations in Crohn’s disease
COMMAND: Long-term efficacy benefits of risankizumab in ulcerative colitis
SEQUENCE: Risankizumab versus ustekinumab across endpoints
QUASAR: Guselkumab improves QoL for patients with ulcerative colitis
Fatigue, urgency, and QoL improvements on mirikizumab in Crohn’s disease
Novel agent VTX002 holds promise in ulcerative colitis
PROFILE: Top-down treatment strategy benefits patients with early Crohn’s disease
Biologicals and JAK inhibitors hold promise in microscopic colitis
Ustekinumab as alternative for anti-TNFs in HLA-DQA1*05-positive Crohn’s disease
How effective is dose escalation of biologicals in IBD?
Promising data for JAK inhibitors in Crohn’s disease from phase 2 trial
U-ENDURE long-term extension: sustained efficacy of upadacitinib in Crohn’s disease
TRIUMPH: Tofacitinib as rescue option for acute severe ulcerative colitis
Should we screen for metabolic bone disease at IBD diagnosis?
Predicting relapse in ulcerative colitis with AI-assisted endoscopy
Clear case for NUDT15 genetic testing in Asian patients with IBD
HELIOS: HD-WLE can yield similar neoplasia detection rates as HD-CE
CURE-CD: Capsule endoscopy-guided proactive treatment leads to fewer relapses in Crohn’s disease
Extended mesenterectomy or mesenteric-sparing surgery in Crohn’s disease?
Similar outcomes for Kono-S and side-to-side anastomosis in Crohn’s terminal ileitis
Risk factors for re-resection in Crohn’s disease revealed
ADMIRE-CD-II: Darvadstrocel does not meet primary endpoint in complex peri-anal fistula
Interview: The winding road to curing metastatic colorectal cancer
Meet the Trialist: Dr Yasuharu Maeda on AI-assisted endoscopy
Adding docetaxel to standard-of-care does not improve outcomes in gastric cancer
Thoracoscopic oesophagectomy non-inferior to open surgery in thoracic oesophageal cancer
KEYNOTE-590: 5-Year outcomes confirm benefit of pembrolizumab in oesophageal cancer
New standard-of-care for locally advanced oesophageal squamous cell carcinoma?
MATTERHORN: FLOT plus durvalumab leads to high pCR rate in gastric cancer
SKYSCRAPER-08: Adding tiragolumab to oesophageal cancer regimen improves outcomes
CheckMate 648: More quality time for patients with oesophageal cancer on nivolumab
CheckMate 649: Nivolumab plus chemotherapy continues to deliver efficacy benefit in gastric cancer
Promising efficacy data for next-gen FGFR inhibitor tinengotinib in CCA
NETTER-2: Practice-changing results for 177Lu-DOTATATE in GEP-NETs
EMERALD-1: TACE plus immunotherapy meets primary endpoint in unresectable HCC
Can adjuvant radiotherapy improve outcomes in resected HCC with narrow margin?
Encouraging preliminary data for glecirasib in pancreatic ductal adenocarcinoma
ALPACA: Promising results for dose de-escalated regimen of gemcitabine/nab-paclitaxel in metastatic PDAC
CheckMate 8HW: Excellent results for nivolumab plus ipilimumab in MSI-H/dMMR mCRC
Can ctDNA-directed therapy improve outcomes in low-risk colon cancer?
Clinical biomarkers may guide therapy selection in RAS wildtype mCRC
Laparoscopic or open surgery in low rectal cancer?
Investigational agent DKN-01 promising for advanced MSS CRC
Interview: Medicare’s first drug price negotiations: concerning?
Letter from the Editor
DIVERSITY1: Filgotinib results in Crohn’s disease leave investigators puzzled
SEQUENCE: Risankizumab doubles endoscopic remission rates compared with ustekinumab in CD
Guselkumab provides benefits in UC regardless of advanced therapy history
INSPIRE: Risankizumab meets all efficacy endpoints in UC
Risankizumab resolves extraintestinal manifestations in CD
Obefazimod takes the spotlight as promising UC treatment
Rapid response to upadacitinib boosts outcomes in severe Crohn’s disease
LUCENT trials: Mirikizumab works in UC, regardless of targeted therapy history
ARTEMIS-UC: New kid in town for UC
Safer removal of large polyps with cold snare technique
Higher recurrence rates with cold snare EMR than with conventional EMR
How to deal with at-risk patients above the CRC screening age limit?
European CRC screening needs to be revised
Epinephrine boosts efficiency in gastric ESD
Artificial intelligence-aided colonoscopy did not improve outcomes in Lynch syndrome
Can computer technology improve our everyday colonoscopy results?
Is AI-assisted colonoscopy ready for clinical practice?
Should we use E-SEMS or EVT for traumatic oesophageal perforations?
Digital intervention relieves symptoms and improves QoL in IBS
GastroGPT: Successful proof-of-concept study of gastroenterology-specific large language model
Primary results from MAESTRO-NASH trial: resmetirom efficacious for NASH
Apraglutide: Advancing the treatment of short bowel syndrome
Endobiliary radiofrequency ablation in pCCA: a pilot study
Raising awareness for microscopic colitis: disease course and predictors
Reprogramming stem cells to heal intestinal mucosa in IBD: fact or fiction?
Linking the Black Death with Crohn’s disease predisposition
Clinics on wheels – Bringing healthcare to patients in underserved communities
EVOLVE Expansion study: vedolizumab and ustekinumab as first-line biologic treatments for Crohn’s disease
Environmental and dietary factors can amplify paediatric IBD risk
Ulcerative colitis: bowel urgency remission associated with improvement in fatigue
Crohn’s disease: Upadacitinib improves endoscopic outcomes in participants with or without previous biologic failure
Durability of SER-109 clinical response in patients with recurrent Clostridioides difficile infection
IBS management: the complex role of dietary fibres
Daily and seasonal fluctuations in the gut microbiome
Colorectal cancer: Aspirin and NSAIDs could reduce the risk of early-onset adenomas
PIPAC technique shows promise for unresectable colorectal peritoneal metastases
Effectiveness of B/F/TAF treatment in HIV/HBV co-infection
Terlipressin shows promise for participants with hepatorenal syndrome and concomitant alcoholic hepatitis
Mepolizumab shows potential in eosinophilic oesophagitis treatment
Dupilumab improves eosinophilic oesophagitis outcomes, regardless of history of oesophageal dilation
Coeliac Disease: “among the top 10 hard-to-diagnose common diseases” – an interview with Dr Cynthia Kelly
IgE-mediated food allergy: increase occurrence of coeliac disease
Children with coeliac disease and anti-tissue transglutaminase antibodies
Characteristics of IBD/coeliac children seropositivity
Updated clinical guidelines for diagnosis and management of coeliac disease
Checking kidney function is important during the course of IBD
Diabetes therapy with GLP-1-based drugs does not elevate the risk of IBD
Long-term resection potentially better than anti-TNF treatment in CD
Early, post-operative complications in CD reduced by pre-operative enteral nutrition, irrespective of biologic exposure
Perinatal period is crucial for the risk of developing CD
Drop in overall IBD procedures during the pandemic
Early-life antibiotic exposure: a risk factor for paediatric-onset IBD
Proton pump inhibitors associated with worse outcomes in CD
Paediatric patients with immune-mediated inflammatory disease harbour a heightened cancer risk
Poor sleep in CD linked to low levels of vitamin D
Novel AI tool assessing mucosal inflammation achieves high correlation with histopathologists
Letter from the Editor
Beneficial effect of early, post-operative vedolizumab on endoscopic recurrence in CD
Long-term data supports the established efficacy and safety of ustekinumab in UC
Anti-TNF withdrawal may be a safe option in stable IBD
Intensified drug therapy leads to better stricture morphology in CD
Continued efficacy of long-term ozanimod as UC treatment
Upadacitinib successful in the management of both CD and UC
Solid results for long-term therapy of UC with filgotinib
Top 14 Medical Innovations for 2022
Letter from the Editor
Immunotherapy response may be modulated by microbiome
Computer-aided colonoscopies improved adenoma detection rates
Screening-detected colorectal cancers may have superior surgical outcomes
Favourable pancreatitis outcomes with procalcitonin-based algorithm to guide antibiotic use
Fewer long-term interventions after delayed drainage in necrotising pancreatitis
Detection of Europe´s deadliest cancer: much room for improvement
Portal hypertension is associated with poor prognosis in cirrhotic patients
Chances of transplant-free survival in PSC enhanced by colectomy with ileostomy
SARS-CoV-2: Booster doses of key importance for cirrhotic patients
Less ulcer bleeds early after H. pylori eradication in aspirin users
Dupilumab effective in paediatric patients with eosinophilic oesophagitis
Neoplasia in Barrett’s oesophagus: the earlier the intervention, the better the long-term outcome
Fast recapture of response with ozanimod after withdrawal in UC
Ozanimod treatment prompted substantial response after failure of response to induction
Etrasimod shows advantage over placebo in UC
Etrasimod reduces adaptive immune cells in the periphery in UC
Favourable maintenance rates for risankizumab also in delayed responders with CD
IL-23 inhibition reduces inflammatory biomarkers in pre-treated UC
Maintained symptom control with mirikizumab in UC
Mirikizumab successfully resolves active histologic inflammation in UC
Upadacitinib for CD: remarkable efficacy in induction therapy
Sustained maintenance results with upadacitinib in UC
Start low with brepocitinib and ritlecitinib in UC
Another chance for TYK2 inhibition in UC
Small molecule obefazimod shows promise in UC
Pivotal results of etrolizumab for CD partly disappointing
Better results for vedolizumab in early CD
Some patients with limited CD may benefit from an early surgical intervention
Dose-interval of adalimumab might be prolonged in CD patients in stable remission
Azathioprine discontinuation linked to genotype regardless of race
Alcoholic cirrhosis is most common liver transplant indication in young U.S. adults
Aggressive treatment of anal lesion prevents more than half of anal cancers in HIV patients
AI-assisted colonoscopy improves adenoma detection
Faecal microbiota transplantation: a safe procedure to treat recurrent Clostridium difficile infections
Oral microbes effective for prevention of recurrent Clostridium difficile infections
Augmented-reality imaging during surgery for bile-duct gallstones reduces residual stones
Octreotide therapy beats standard of care in GIADs
Improvement in hepatic steatosis but worse lipid profile after alcohol cessation
Normal BMI in NAFLD patients is associated with a higher risk of cardiovascular disease
COVID-19 increases the mortality rates of patients with ALD
Substantial increase of oesophageal cancer prevalence in the middle-aged
Cannabis users need more sedation medication for gastroscopy
Preterm delivery and NICU admission are associated with the development of eosinophilic oesophagitis
Dupilumab promising as treatment for eosinophilic oesophagitis
Antibiotic use elevates IBD risks in senior citizens
Too much hygiene: CD in later life?
Biologic treatment decreases dementia risk in senior IBD patients
CD: Induction treatment with upadacitinib successful in clinical and endoscopic ratings
IL-23 inhibition beneficial in maintenance treatment of UC
Positive outcomes for etrasimod in UC
Colonoscopy in UC: less pain and reduced recurrence with CO2 insufflation
Variceal embolization during TIPS placement does not reduce rebleeding
Letter from the Editor
Lessons from the COVID-19 pandemic for IBD management
AI model distinguishes between histologic activity and remission in ulcerative colitis
Multi-Omic and dietary analysis of Crohn’s disease identifies pathogenetic factors
Novel classification system for perianal fistulising Crohn’s disease
Vaccination tool associated with improved vaccination coverage in IBD
Comparable safety profiles of biological therapies in elderly patients with IBD
Early biologic therapy induces larger effect than delayed treatment in Crohn’s disease
RESTORE-UC: No better outcomes with FMT superdonors than with autologous stools
Positive outcomes with therapeutic drug monitoring during infliximab maintenance therapy
Segmental colectomy beneficial over total colectomy in Chrohn’s disease
Modified 2-stage ileal pouch-anal anastomosis versus 3-stage alternative
Similar results for different corticosteroid tapering protocols in UC
Ozanimod treatment shows maintained response in ulcerative colitis
Stopping infliximab but not antimetabolites leads to more relapses in Crohn’s disease
Vedolizumab first approved therapy for chronic pouchitis
VEDOKIDS: Vedolizumab seems effective in paediatric IBD
Primary endpoint of 5-hydroxytryptophan for fatigue in IBD not met
Anti-TNFs versus vedolizumab and ustekinumab in Crohn’s disease
Upadacitinib appears to be an efficacious therapy for moderately-to-severely ulcerative colitis
Subcutaneous infliximab versus subcutaneous vedolizumab in IBD
Vedolizumab outperforms anti-TNF in biologic-naïve ulcerative colitis
Guselkumab shows encouraging safety and efficacy in ulcerative colitis
Guselkumab maintenance therapy achieved high efficacy rates in Crohn’s disease
Mirikizumab efficacious for active ulcerative colitis
Risankizumab more efficacious in colonic than in ileal Crohn’s disease
Guselkumab plus golimumab promising combination for ulcerative colitis
Combined endpoint may support personalised medicine in ulcerative colitis
Filgotinib seems promising for perianal fistulising Crohn’s disease
Upadacitinib maintenance therapy delivers sustained improvements in active ulcerative colitis
Upadacitinib counters extraintestinal manifestations in ulcerative colitis
Upadacitinib effector pathways unravelled
Deucravacitinib does not meet primary endpoint for ulcerative colitis
Early parenteral nutrition support cuts infections after major abdominal surgery
Transcutaneous electrical acustimulation may help ease functional constipation
Cancer detection likely similar for one-time colonoscopy or two fecal immunochemical tests
GLP-1 receptor agonists may increase risk of gallbladder or biliary disease
Metastasis rate high after endoscopic resection of high-risk T1a esophageal cancers
Cumulative exposure to tacrolimus tied to post liver transplant cancer risk
Sintilimab plus FOLFIRINOX may provide benefits in metastatic pancreatic cancer
TRYbeCA-1: Eryaspase + chemotherapy does not meet primary endpoint in pancreatic cancer
Persisting disparities in pancreatic cancer care
ctDNA promising biomarker for recurrence of pancreatic cancer
Letter from the Editor
Head-to-head: Etoposide and irinotecan equally effective in neuroendocrine carcinoma
EMR versus ESD in oesophageal cancer
Pre-operative chemoradiation versus peri-operative chemotherapy for oesophageal cancer
AK104 plus chemotherapy promising first-line option for gastric cancer
DESTINY-Gastric01: OS benefit of T-DXd over chemotherapy for HER2-positive gastric cancer
The emerging role of AI in gastroesophageal cancer
DCF outperforms standard-of-care for locally advanced oesophageal cancer
Nivolumab in gastric cancer: Efficacy update and the role of gut microbiome
Updates on pembrolizumab for oesophageal and gastric cancer
NIPICOL: New data on optimal ICI treatment duration in MSI/dMMR mCRC
Dostarlimab may offer an alternative for dMMR rectal cancer
DESTINY-CRC01: Maintained efficacy of T-DXd in mCRC
Key updates in colorectal cancer screening
Impact of COVID-19 on screening for colorectal cancer
Nivolumab plus standard-of-care does not meet primary endpoint for mCRC
No benefit of additional oxaliplatin in elderly patients with mCRC
Prognostic impact of early oxaliplatin discontinuation in colon cancer unravelled
Long-course chemoradiation versus short-course radiotherapy in rectal cancer
Adjuvant S-1 therapy superior to observation in resected biliary tract cancer
Pembrolizumab safe and efficacious in advanced hepatocellular carcinoma
TOPAZ-1: Adding durvalumab to chemotherapy effective in advanced biliary tract cancer
HIMALAYA: Durvalumab ± tremelimumab new first-line option for unresectable HCC
LAUNCH: TACE plus lenvatinib efficacious in advanced HCC
Modest activity of atezolizumab plus bevacizumab in Child-Pugh B HCC
Early transplant for severe alcoholic hepatitis boosts survival, alcohol intake
Irregular periods may put women at risk for liver disease
p53 mRNA nanotherapy plus anti-PD-1 therapy reverse immunosuppression in a liver cancer model
Sponge-on-a-string device helps detect, monitor early esophageal neoplasia
Early-onset colorectal cancer in young patients is often advanced at diagnosis
BRCA1/2 pathogenic variants linked to prostate, pancreatic and stomach cancers
No benefit to adding trastuzumab to neoadjuvant chemoradiation for HER2 esophageal cancer
Neoadjuvant cemiplimab promising for resectable liver cancer
Antihyperglycemic drugs likely effective for NAFLD
Stem cell-derived pancreatic cells may be alternative to islet transplants
Women with IBD expect their gastroenterologist to initiate discussion of reproductive health
Spore therapy cuts C. difficile reinfection by 68% in 8-week study
No need to repeat celiac screening for five years after negative serology
Gastrointestinal PCR panel enables faster, better antibiotic therapy in kids with infectious diarrhea
Overweight, obesity in early adulthood tied to higher risk of early-onset colorectal cancer
Crohn’s strictures may respond to immunosuppressive drug therapy
Greater intestinal permeability seen with bile acid diarrhea than IBS diarrhea
Simple scoring system may safely reduce abdominopelvic CT in Crohn’s patients
Antibiotics plus oral fecal microbiota transplantation tied to ulcerative colitis remission
Immune checkpoint inhibitors likely best standard therapies for unresectable liver cancer
CRISPR/Cas9 gene editing boosts effectiveness of sonodynamic therapy for liver cancer in mice
Pre-op chemosensitivity tied to post-op survival in patients with gastric tumors
Lowering of CRC-screening age likely to affect colonoscopy demand, case mix, adenoma detection
Etrolizumab down but not out for ulcerative colitis: studies
Crohn’s disease exclusion diet may produce remission of mild-to-moderate disease
Diet that promotes sulfur-metabolizing bacteria tied to colorectal cancer risk
A single flexible sigmoidoscopy screening tied to long-term protection against colorectal cancer
Assisted reproductive therapy safe in women with IBD but efficacy mixed
Transit bipartition an attractive second-step option when sleeve gastrectomy fails
External-beam radiation underused in people with liver cancer awaiting transplant
Should all bariatric-surgery patients take ursodeoxycholic acid to prevent gallstones?
In people on NSAIDs, SSRI antidepressant may further up risk of GI bleeding
More adults embraced at-home colorectal-cancer screening during pandemic
New drug for short-bowel syndrome offers hope of simplified treatment
Add-on ramucirumab increases PFS, not overall survival, in East Asians with advanced gastric cancer
Adenomas detected per colonoscopy a valid quality measure tied to lower post-colonoscopy CRC
Risankizumab meets primary endpoints in maintenance study for CD patients
Ustekinumab treat-to-target strategy offers long-term alternative for standard-of-care in CD
Long-term efficacy data of dupilumab for eosinophilic oesophagitis
Upadacitinib efficacious and safe as maintenance therapy for UC
Upadacitinib outperforms placebo in UC patients with inadequate response to biologics
Rapid symptom control for UC patients on upadacitinib
Filgotinib demonstrates promising results for various lines of therapy in UC
Filgotinib demonstrates long-term corticosteroid-sparing effects in UC
Long-term benefits of tofacitinib for substantial proportion of UC patients
Ritlecitinib and brepocitinib are promising JAK inhibitors for UC
First pharmacological therapy with clear efficacy in coeliac disease patients
Serologic response to COVID-19 mRNA vaccine reduced in IBD patients on anti-TNFα
Serious adverse events put a stop to ASTIClite trial for CD
Motorised spiral enteroscopy safe in real-life and in patients with altered anatomy
Novel tool can reliably exclude submucosal invasion in colorectal polyps
Home infusion safe for IBD patients receiving infliximab and vedolizumab
Surgery needed in nearly half of appendicitis patients treated with antibiotics
UEGW 2021 Highlights Podcast
Percutaneous endoscopic gastrostomy may be less risky for long-term tube placement
NAFLD may be independent risk factor for cardiovascular morbidity and mortality
Rising rates of esophageal cancer in young adults, lifestyle may be to blame
Rectal compliance lower than normal in ulcerative colitis but recovery is possible
Relatives of patients with colorectal carcinoma in situ at higher risk for colorectal cancer
Biopsy may not be needed to treat immune checkpoint inhibitor-associated hepatitis
Antibiotics tied to increased risk of colorectal cancer
Combined chemoembolization and ablation effective for early-stage hepatocellular carcinoma
Robotic-controlled, fully automated capsule endoscopy on par with conventional method
Live varicella-zoster vaccine safe, effective with TNF inhibitors
Could steroid treatment speed recovery from infliximab-induced liver injury?
Sleeve gastrectomy safe and effective long-term in kids with severe obesity
Mirati drug combination shrinks tumors in 39% of colon cancer patients in study
Clinicians see barriers to colonoscopy completion after abnormal fecal test
New guidelines provide framework for safe liver transplantation for non-resectable colorectal liver metastases
Screening and treating H. pylori in those at high risk for gastric cancer appears cost-effective
Subcutaneous vedolizumab appears effective maintenance therapy in Crohn’s disease
Adalimumab biosimilar on par with original in Crohn’s disease
More-aggressive therapy not warranted for early-onset colorectal cancer
AI improves detection of gastric neoplasms during routine endoscopies
Pertuzumab plus trastuzumab promising in HER2-positive biliary-tract cancers
New target to dial down inflammation and pain discovered
Early cholecystectomy for mild gallstone pancreatitis may also have economic benefits
Perioperative SOX protocol bests adjuvant CapOx in locally advanced gastric cancer
Gut-microbiome changes may precede celiac disease onset in at-risk children
Rectal diclofenac likely comparable to rectal indomethacin for post-ERCP pancreatitis
TAVI safe and effective in patients with inflammatory bowel disease
Study supports chemopreventive effect of statins on liver cancer in NASH cirrhosis
Pfizer-BioNTech vaccine effectiveness comparable in IBD patients, general population
Donafenib yields survival advantage over sorafenib in Chinese patients with advanced liver cancer
Variation seen in radiologist recommendations for small cystic pancreatic lesions
Psychological problems common in IBS, may worsen prognosis
Drug attenuates duodenal damage from gluten in celiac disease
Adalimumab safe and effective in children with ulcerative colitis
No increased risk of (severe) COVID-19 among IBD patients
Blood proteins predicting relapse in CD identified
Similar efficacy of ustekinumab and adalimumab for moderate-to-severe CD
Upadacitinib meets primary endpoint for moderate-to-severe UC
Oral faecal microbiota transplant therapy efficacious in UC
Extracellular RNA has potential as a non-invasive biomarker in IBD
Ustekinumab safe and effective in elderly CD patients
Promising safety and pharmacokinetic data on BT051 for UC
Artificial intelligence outperforms human classifying of endoscopic images in UC
Early clinical remission and response following risankizumab therapy in CD
Surgical closure plus anti-TNF outperforms anti-TNF alone for perianal fistula
Increased risk of rectal cancer after colectomy in IBD
Risk of hospitalisation and surgery linked to IBD biological
Risk of colorectal cancer is detected by low-pass whole genome sequencing
Large variability in IBD care and education across Europe
Ultra-processed food intake associated with IBD
Factors of coping difficulties in IBD revealed
Obesity increases the risk of immunogenicity to adalimumab in IBD
Contrast-free imaging can spot post-op Crohn’s recurrence
How do three natural remedies for chronic constipation measure up?
Apatinib boosts survival in Chinese patients with advanced liver cancer
Specific carbohydrate diet not superior to Mediterranean diet for Crohn’s disease
Childhood celiac disease may be on the rise
Patients with advanced esophageal cancer can skip chemo with upfront dual immunotherapy combo
Esophageal dilation using a novel attachment cap clinically effective in EoE
FMT an option in severe refractory cases of C. difficile, new guideline says
Smart toilet analyzes stool to aid remote management of GI disorders
Probiotics might help guard against upper respiratory symptoms
PARP inhibitor rucaparib helps shrink pancreatic tumors with mutations
Web-based patient education cuts down upper GI endoscopy for dyspepsia
Stopping infliximab linked to relapse in ulcerative colitis
Stool-based tests boosted declining screening rates for colorectal cancer during pandemic
Fecal microbiota transplantation impacts microRNAs implicated in recurrent C. difficile
mRNA COVID-19 vaccines effective in IBD patients receiving biological therapies
Adding aprepitant to other antiemetics further prevents chemo-induced nausea and vomiting
HER2 results in gastric cancer often differ between labs with implications for treatment
Chemoprevention with low-dose aspirin promising in familial adenomatous polyposis
Surgery after chemo can improve survival in stage 2 pancreatic cancer
Aggressive hydration ‘not justified’ for post-ERCP pancreatitis prophylaxis
Nivolumab doubles disease-free survival when residual esophageal cancer lurks
Bariatric surgery tied to reduced breast cancer risk, earlier diagnosis
IBD patients should be screened for anxiety, depression
Hypofractionated ablative radiation tied to improved survival in pancreatic cancer
Liquid biopsy after hepatectomy promising aid in metastatic colorectal cancer
First-line pembrolizumab shows superior PFS in MSI-H/dMMR mCRC
Short-course radiotherapy with delayed surgery better for elderly rectal cancer patients
Bemarituzumab response for gastric/GEJ cancers correlates with FGFR2b levels
Circulating tumour DNA predicts recurrence in colorectal cancer
Gut microbiome DELIVERs nivolumab forecast in gastric cancer
Ivosidenib in second-line improves OS in IDH1-mutant cholangiocarcinoma
Neoadjuvant pembrolizumab in locally-advanced rectal cancer: primary results
OS benefit for trifluridine/tipiracil in advanced gastric cancer from third-line onward
Prognostic value of tumour deposits in stage 3 colon cancer patients
Final phase 2 results of second-line infigratinib for advanced cholangiocarcinoma
Neoadjuvant chemotherapy does not increase perioperative complications in thoracic oesophageal cancer
Ipilimumab/nivolumab plus panitumumab in patients with microsatellite-stable mCRC
Adjuvant nivolumab: good quality-of-life
Preliminary surgery salvage data after watch & wait policy from OPERA trial
Landmark OS for HCC, updated IMbrave150 data
Adding docetaxel to adjuvant S-1 reduces gastric cancer relapse
Second-line pembrolizumab after progression on sorafenib benefits OS/PFS in advanced HCC
Predicting resistance to first-line FOLFOX plus bevacizumab in mCRC using circulating markers
Phase 2 study supports first-line pembrolizumab in advanced HCC
Final OS analyses comparing trifluridine/tipiracil + bevacizumab versus capecitabine + bevacizumab in first-line unresectable mCRC patients noneligible for intensive therapy
Yttrium-90 (Y-90) glass microspheres for HCC
Maintenance treatment with cetuximab versus observation in RAS wildtype mCRC
Duloxetine ameliorates oxaliplatin-induced peripheral neuropathy
Sorafenib extends PFS, but not OS, for HCC transcatheter arterial chemoembolisation
Zanidatamab provides ORR in HER2+ biliary tract cancer
Letter from the Editor
Borderline resectable pancreatic cancer: phase 2 results
No survival benefit for olaparib in BRCA-mutated metastatic pancreatic cancer
Metastatic pancreatic adenocarcinoma: second-line naI-IRI plus 5-FU/LV
COVID-19 impact on gastrointestinal cancer care
Treatment delay for cholangiocarcinoma adjuvant therapy does not affect OS
No benefit of adding axitinib to ocreotide acetate in non-pancreatic neuroendocrine tumours
Phase 2 abemaciclib trial in patients with advanced NETs
Neoadjuvant chemo for intrahepatic cholangiocarcinoma may prolong life
PICaSSO tool promising for predicting histologic remission in ulcerative colitis
No survival benefit to primary resection before chemo in metastatic colorectal cancer
Amoxicillin-clavulanate safe, effective for uncomplicated diverticulitis
Ustekinumab works well in ulcerative colitis in the general population
Reassuring data on immune checkpoint inhibitors in autoimmune disease
Adherent-invasive E. coli metabolism drives inflammation in Crohn’s disease
Robotic total gastrectomy pricier, but has some advantages over traditional laparoscopic approach
Hirschsprung disease tied to increased risk of inflammatory bowel disease
Drug combo yields longest-ever survival in advanced liver cancer
IBD patients with clinical remission often malnourished, sarcopenic
Rifaximin may prevent hepatic encephalopathy after TIPS placement for cirrhosis
IV ferric carboxymaltose tops IV iron sucrose for iron-deficiency anemia in IBD
Cigarette smoke tied to colorectal neoplasia in IBD patients
Promising longer-term data for etrasimod in ulcerative colitis
Bariatric surgery may curb diabetic eye disease incidence but worsen existing retinopathy
Radiotherapy for rectal cancer linked to risk for later malignant gynecological neoplasms
Organ preservation possible in early-stage rectal cancer
Radiotherapy then chemotherapy before surgery may be best in rectal cancer
Noninvasive fibrosis tests predict clinical, patient-reported outcomes in advanced NASH
Carcinoid tumors increasing in young adults at a faster clip than adencarcinomas
Health, well-being of children with Hirschsprung’s disease seriously impaired
Anti-cytokine therapy normalizes ACE2 expression in IBD, may protect against COVID-19
No survival differences with open or laparoscopic surgery for liver metastases
Semaglutide effective against nonalcoholic steatohepatitis in phase-2 trial
Risk-adapted starting ages proposed for colorectal cancer screening in diabetics
Pembrolizumab prolongs overall survival in some with advanced esophageal cancer
Race, ethnicity affect epidemiology and management of inflammatory bowel diseases
Sustained efficacy of mirikizumab in moderate-to-severe Crohn’s disease
Low-FODMAPs diet does not improve PPI-refractory GERD
Probiotic provides a potential adjuvant treatment to gluten-free diet
Cholecystectomy does not affect mortality in elderly patients
No improvements of remission with etrolizumab in ulcerative colitis
Filgotinib effective as maintenance treatment for ulcerative colitis
Possible causal link between eosinophilic inflammation and anxiety
Dupilumab improves in diverse aspects of eosinophilic oesophagitis
Plecanatide effective for IBS with constipation
Sustained response to faecal microbiota transplantation
Endoscopy can be delivered safely during the COVID-19 pandemic
Adenoma detection rate improves over time
Post-colonoscopy colorectal cancers in IBD patients
Risk factors for severe COVID-19 among IBD patients
First randomised T2T trial using endoscopy to guide dose escalation
Cobitolimod might induce remission in moderate-to-severe left-sided ulcerative colitis
Per-oral endoscopic myotomy “reasonable” first-line treatment for idiopathic achalasia
Bioenhanced curcumin may induce remission in ulcerative colitis
Colorectal cancer more likely after first acute diverticulitis
Linked color imaging bests conventional imaging for upper GI cancer detection
Invasive features, positive margins tied to worse outcome of precancerous pancreas lesions
Bariatric surgery increases life expectancy in large Swedish study
Surufatinib improves progression-free survival in advanced pancreatic neuroendocrine tumors
IBS symptoms common in patients with IBD in remission
MR-Linac-delivered adaptive radiation therapy promising in pancreatic cancer
Antibiotics prove noninferior to surgery for appendicitis in large trial
Vascular invasion, tumor deposits more prognostic than TNM for rectal cancer
High-dose digestive enzymes prevent NAFLD after pancreaticoduodenectomy
Celiac disease tied to increased risk of major osteoporotic fractures
Gasless laparoscopy provides minimal-access surgery in resource-limited countries
Eflornithine-sulindac combo may not offer extra benefit for familial adenomatous polyposis
New guidelines expand management options for hereditary hemorrhagic telangiectasia
Too much fructose disrupts intestinal barrier in mice, leading to liver damage
Resolution of mucosal inflammation has dramatic effect
PICaSSO validated in real-life study
Re-inducing inflammation in organoids from UC patients
Role of immune cells in intestinal fibrosis
Association between meat consumption and IBD risk
CD exclusion diet corrects dysbiosis
Increased risk of small bowel cancer in IBD
Increased incidence of colorectal cancer and death in CD
Risk of rectal, anal cancer increased in perianal CD
Glyco-fingerprint as risk factor of UC-associated cancer
Effects of vedolizumab versus adalimumab on QoL
Vedolizumab and anti-TNF therapies: a real-world comparison
Vedolizumab, adalimumab, and golimumab compared
Vedolizumab versus ustekinumab
On the cutting edge of pathology and surgery
Impact of strategies on intestinal resection rate
Early ileocaecal resection in CD patients failing conventional treatment
Biologics before surgery in IBD do not elevate infection risk
Top-down infliximab superior to step-up in children with CD
High versus standard adalimumab in active UC
Infliximab discontinuation increases relapse risk
Tofacitinib ‘real-world’ effectiveness in active UC
Ustekinumab in CD: a T2T trial
Subcutaneous ustekinumab as maintenance therapy in UC
Subcutaneous vedolizumab maintenance therapy in CD
Vedolizumab treatment persistence and safety
Pipeline of IBD drugs
AMT-101: an oral human IL-10 fusion protein
Phase 2 results of first-in-class TL1A inhibitor
Open-label extension study of risankizumab: final results
Clinical remission after dose escalation of upadacitinib
Response to faecal microbiota transplantation in UC
Multi-omics help describe CD phenotypes
The positive impact of genetic data on drug development
Impact of biologicals on faecal microbiota
Bioactives produced by gut bacteria to modulate immune response
Letter from the Editor
Interview with UEG President Prof. Paul Fockens
Practice-changing: infliximab in children with Crohn’s
Ustekinumab is safe and effective in ulcerative colitis: 2-year data
Ileal microbiota predict recurrence in CD patients after resection
Early stages of gastric metaplasia: molecular profiling
Decreased microvilli length in CD patients
Faecal microbiota transplantation is effective for irritable bowel syndrome
New model predicts recurrence of acute biliary pancreatitis
Locally active corticosteroid promising in eosinophilic oesophagitis
EUS-guided histological specimens from the pancreatic cyst wall
Metal stents are better than plastic for endoscopic biliary drainage
Restrictive strategy for cholecystectomy selection does not reduce pain, but does reduce surgery
Plant-based foods and Mediterranean diet associated with healthy gut microbiome
Phase 2 data shows benefit for mirikizumab in CD patients
Ramosetron relieves low anterior resection syndrome
β-blockers may halt cirrhosis progression: PREDESCI trial
Subcutaneous ustekinumab as maintenance therapy in UC
Half of common medications wreak havoc on gut microbiome
Digital single-operator cholangioscopy more sensitive than endoscopic retrograde cholangiopancreatography
Global burden of digestive diseases reveals alarming trends
First evidence of long-term efficacy of ABX464 in ulcerative colitis
Immunonutrition during neoadjuvant oesophagogastric cancer therapy: no benefit
Obeticholic acid prevents liver fibrosis from NASH
Interim data on GOULASH-PLUS trial
Human milk oligosaccharides improve IBS symptoms
First-in-human radiofrequency vapor ablation in Barrett’s oesophagus
New treatment may reverse coeliac disease
New single-use duodenoscope well-liked by endoscopists
IBD prevalence 3 times higher than estimated and expected to rise
Antibiotic resistance in H. pylori has doubled over last 20 years
The right drug for the right patient
Topical review
Letter from the Editor
Vedolizumab superior to adalimumab in ulcerative colitis
Complementary and alternative medicine associated with chronic fatigue and lower QoL
Selective oral sphingosine 1-phosphate receptor modulator amiselimod
Vedolizumab: Results from the GEMINI programme
Crohn’s disease exclusion diet + partial enteral nutrition in paediatric Crohn’s disease
Novel host-microbiome interactions in inflammatory bowel disease
Pathogenesis
The costs and benefits of biologicals
Selective sphingosine-1-phosphate receptor modulator etrasimod
Ustekinumab as maintenance therapy and with shortened interval
Early remission of Crohn’s disease prevents progression
Microbial composition and psychological wellbeing
Immune cells and microbes: a happy marriage?
Efficacy and safety of biosimilars
Tofacitinib: Results from the OCTAVE open-label studies
Histological remission predicts relapse-free survival in ulcerative colitis
Gene expression signature predicts non-response
OPERA II study: MAdCAM-1 antibody SHP647
Safety of thiopurine + allopurinol vs thiopurine monotherapy
Upadacitinib: data from U-ACHIEVE and CELEST
Limited long-term effectiveness and safety of tacrolimus in ulcerative colitis
Cyclosporine: novel low-dose, controlled-release formulation
IBD risk of treatment with IL-17 antagonists
Interview with Prof. Janneke van der Woude
Proactive adalimumab trough measurements
Glycans as novel immunomodulators in inflammatory bowel disease
Quiescent disease, characteristics and biomarker correlations
Enhanced post-operative recovery pathways for IBD patients
Combining new drugs with different mechanisms
Long-term risk of advanced neoplasia after colonic low-grade dysplasia in IBD
Vedolizumab in anti-TNF-naïve IBD patients and safety profile
Higher colectomy rate with infliximab vs conventional therapies in more severe UC
Cobitolimod induces anti-inflammatory effects by balancing Th17/T-reg cell response
Cancer risk in IBD associated with age and recent immunomodulator use
Long-term safety profile of adalimumab
Significant reduction of emergency stoma surgeries for CD
Shallow whole-genome sequencing predicts future cancer risk of LGD in UC
Overall manageable safety profile of tofacitinib in long-term use
Central role of IL-23 in molecular resistance to anti-TNF therapy
Early and significant effects with upadacitinib induction treatment
