I hope you will enjoy our Medicom Conference Report of this year’s ASCO GU Symposium.
As usual, I’ll just sample some abstracts as “teasers”:
As you will see, we are coming closer to implementing a personalised medicine approach to prostate cancer, with both new prognostic and predictive markers identified.
LuPSMA has been used in daily practice for years in some European countries – now there’s more evidence that this was/is justified.
A new target, a new conjugate – very promising results in advanced bladder cancer treatment.
This comes at a price – and we are increasingly at odds to pay for. Please read the interesting article on the necessary overhaul of licensing and reimbursement of oncology drugs.
So, how about repurposing a cheap drug? Is there a new role for ACE inhibitors in bladder cancer treatments? It may be a little early for that, as this is retrospective data – and there’s a long history of supposedly promising but finally inefficient repurposed drugs in oncology. Still..
Please enjoy our congress report.
Yours, sincerely,
Stefan Rauh
Biography
Dr Stefan Rauh is currently working as haemato-oncologist in the oncology department of Centre Hospitalier Emile Mayrisch, Esch, Luxembourg. He is mainly involved in clinical work but also in research and teaching activities and is interested in public policy and international cooperation projects in oncology. He is member of the ESMO Practicing Oncologist’s Working Group since 2011 (chair 2014–2018), member of the ESMO Public Policy Committee, and has been an ESMO Executive Board member in 2015–2016. He is co-author of the 2017 ESMO European Cancer Patient Coalition (ECPC) Patient Survivorship Guide and an invited expert for the ECPC.
Conflicts of interest: Nothing to declare.
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Table of Contents: ASCO GU 2021
Featured articles
Prostate Cancer
Lu177 as a promising new therapy for metastatic prostate cancer
Role of prostate cancer genomics is evolving
Apalutamide prolongs progression-free survival in prostate cancer
Dose-intensified radiation therapy fails to provide better outcomes in prostate cancer
Intrinsic tumour biology may be predictive of treatment response in prostate cancer
Final TITAN trial results favour use of apalutamide
Penile Cancer
Prognosis of penile cancer associated with HPV status
Renal Cancer
Superior clinical outcomes and QoL with nivolumab plus cabozantinib in RCC
Lenvatinib plus pembrolizumab prolongs survival in renal cell carcinoma
Inflammatory markers may guide treatment decisions in metastatic renal cell cancer
Clinical trial exclusion criteria may lead to lack of evidence in real-world patients: how do the excluded fare?
Axitinib offers hope for improving renal cell cancer surgical outcomes
Cabozantinib as possible new first-line therapy in translocation renal cell carcinoma
Predictors of oral anti-cancer agent utilisation in renal cell carcinoma
Denosumab plus pembrolizumab in advanced clear cell renal cell carcinoma
Testicular Cancer
New prediction model for brain metastasis in germ cell tumours
Reduction in radiation exposure is possible in testicular seminoma surveillance
New therapeutic option for early metastatic seminoma
Urothelial Cancer
Poorer outcomes in bladder cancer predicted by race/ethnicity and gender
Enfortumab vedotin as a promising treatment option for bladder cancer: phase 3 results
Enfortumab vedotin as a promising treatment option for bladder cancer: phase 2 results
New standard of care recommended for patients with upper tract urothelial cancer
Signature DNA alterations in subtypes of bladder cancer
ACE inhibitors associated with superior responses in bladder cancer
Better allocation of research dollars needed
Better prediction of favourable responses to immune checkpoint inhibitors in mUC
Genitourinary Oncology
Researchers call for an overhaul of licensing and funding of anti-cancer drugs
Exploring a new strategy for metastatic germ cell tumours
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