This year’s European Academy of Neurology meeting welcomed participants in Budapest, Hungary with nearly 8,000 neurologists participating in this event that highlighted
research from all areas of neurology. Much news was communicated regarding diagnostic,
therapeutic, and pathogenetic advances in subdisciplines like multiple sclerosis, cerebrovascular disease and stroke, epilepsy, the dementias, and sleep disorders. Cutting-edge research related to elucidating the etiopathogenesis were presented, as well as results of new treatment trials for
neurological conditions across the board. As always, our summaries are written independently and are peer-reviewed for balance.
We hope you find this edition informative, engaging, and balanced and thank you again for
your readership.
Best wishes,
Prof. Hans-Peter Hartung
FRCP FEAN FAAN FANA
Biography
Prof. Hartung is currently Professor of Neurology at Heinrich-Heine-University Düsseldorf, Honorary Professor at Brain and Mind Center, University of Sydney, Visiting Professor at Medical University Vienna and Palacky University Olomouc. He was chairman of the Department of Neurology, Heinrich-Heine-University Düsseldorf from 2001-2020, director of the Center for Neurology and Neuropsychiatry from 2012-2020 and director of the Department of Conservative Medicine from 2012-2019.
Prof. Hartung’s clinical and translational research interests are in the field of basic and clinical neuroimmunology and in particular multiple sclerosis and immune neuropathies, development of new immunological, neuroprotective and neural repair promoting strategies. He has (co-)authored more than 950 articles in peer-reviewed journals and 100 book chapters. He has been involved as member of the Steering Committee in numerous international multicentre therapeutic phase 2 and 3 trials in multiple sclerosis, Guillain-Barré Syndrome and CIDP.
He was President of ECTRIMS and has served/ serves amongst others on the executive boards of the European Charcot Foundation, the European Neurological Society, and the International Multiple Sclerosis Cognition Society (IMSCOGS). He is/was also member of the Editorial Board of a number of international journals. Prof. Hartung is a Fellow of the AAN and EAN, and has been chair/ member of the management group of the EAN scientific panels on general neurology and multiple sclerosis. He is Corresponding and Honorary Fellow of several international societies.
Conflict of Interest Statement:Hans-Peter Hartung has received fees for consulting, speaking, and serving on steering committees from Bayer Healthcare, Biogen, GeNeuro, MedImmune, Merck, Novartis, Opexa, Receptos Celgene, Roche, Sanofi Genzyme, CSL Behring, Octapharma, Teva, TG Therapeutics, and Viela Bio, with approval by the Rector of Heinrich-Heine University.
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Table of Contents: EAN 2023
Featured articles
Letter from the Editor
Alzheimer’s disease and dementia: the road towards proactive and preventive care
Overarching Theme: Big Data
Contribution of genomics and genetics to personalised medicine
How big data can boost care for neurodegenerative disorders
COVID-19
Amantadine in early COVID-19 enhances recovery
SARS-CoV-2 vaccination in CIDP and MMN: more benefit than harm
Cerebrovascular Disease and Stroke
Intensive BP reduction associated with smaller haematoma
Cognition and Dementia
Towards cell biology of Alzheimer’s disease
Epilepsy
Minimising co-medication optimises cenobamate efficacy in drug-resistant epilepsy
Headache and Pain
GLP-1 agonists induce weight loss and alleviate headache in idiopathic intracranial hypertension
Cannabis-based medicine does not beat placebo in central neuropathic pain
80% of patients reverse from chronic to episodic migraine on anti-CGRP antibodies
Multiple Sclerosis
Which patients can initially be treated with platform DMT?
Retinal layer thickness predicts disability accumulation in early RMS
Withdrawing DMF in early pregnancy does not increase relapse risk in pregnant patients with MS
Immunosenescence and MS: relevance to immunopathogenesis and treatment
Sleep Disorders
Nightmares during childhood linked to cognitive decline later in life
Sleep changes contribute to the pathogenesis of neurodegenerative diseases
Miscellaneous
EAN guidelines on the management of ALS
What neurologists should know about bladder and sexual problems
Laughing gas abuse often leads to polyneuropathy, myelopathy, and encephalopathy
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