Algorithm-based remote patient monitoring was associated with lower mortality in a retrospective cohort study

In the French TELESAT study, the use of an algorithm-based remote patient monitoring (RPM) programme was associated with lower all-cause mortality in patients with heart failure (HF) compared with standard-of-care (SOC) in a non-randomised cohort study.

TELESAT (NCT06312501) was a multicentre, observational, retrospective, longitudinal cohort study designed to evaluate the ability of an RPM programme to prevent cardiac decompensation by detecting early weak signals of decompensation in patients with chronic HF in France. Prof. Nicolas Girerd (University Hospital of Nancy, France) presented the results of this large-scale study that included over 300 centres and almost 19,000 participants with HF.

The RPM group consisted of 5,467 patients and the retrospective cohort receiving SOC included 29,808 patients. Their mean age was 71.8 years, 68% were men, 68% had coronary disease, 56% had hypertension, and 86% had dyslipidaemia. The evaluable population consisted of 5,357 participants in the RPM group and 13,525 in the SOC group; over half of the participants in the SOC group were excluded from the analysis because of propensity score. The RPM group received a personalised telemedicine solution (device: Satelia® Cardio), which monitors clinical signs (i.e. HF symptoms and weight) and provides personalised education through its application, whereas the SOC group did not use any remote monitoring. In the RPM group, participants were asked simple questions and consequently given a score that was transmitted to the healthcare providers, who could then institute the appropriate responses.

Figure: The primary outcome of the TELESAT study: all-cause mortality [1]



RPM, remote patient monitoring; SOC, standard-of-care.

“An algorithm-based RPM based on symptoms and weight monitoring, with personalised frequency and tailored therapeutic education, was associated with lower all-cause mortality compared with standard care within the French healthcare system,” concluded Prof. Girerd. “This benefit seemed particularly pronounced in digitally illiterate patients, who generally constitute a significant portion of elderly individuals with HF at high risk.”

1. 
   
   1. Girerd N, et al. Impact of a remote monitoring program on all-cause mortality of patients with heart failure: National, real-world evidence of the TELESAT study. Late breaking clinical trials I, Heart Failure 2024, 11–14 May, Lisbon, Portugal.

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Posted on 16 July 202416 July 2024