Letter from the Editor EditorDr Stefan Rauh, Centre Hospitalier Emile Mayrisch, Esch, Luxembourg ConferenceESMO 2019 26 November 2019 23:32
Interview with ESMO President Prof. Josep Tabernero ExpertProf. Josep Tabernero, Vall d’Hebron University Hospital, Barcelona, Spain ConferenceESMO 2019 26 November 2019 13:32
Triple negative breast cancer gets positive news: KEYNOTE-522 interim results Presented ByProf. Peter Schmid, Queen Mary University of London, UK TrialPhase 3, KEYNOTE-522 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:12
CDK4/6 inhibitors change landscape of breast cancer treatment: 2 studies Presented ByProf. Dennis Slamon, Prof. George Sledge, Prof. Nadia Harbeck TrialMonaleesa-3, Monarch 2 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 22:03
Veliparib-chemo combo prolongs survival without disease progression in some advanced breast cancer patients Presented ByVeronique Diéras, Centre Eugène Marquis, Rennes, France TrialPhase 3, BROCADE 3 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:04
Improved response rates without survival benefit with pembrolizumab in pretreated mesothelioma Presented ByDr Sanjay Popat, Royal Marsden Hospital NHS Foundation Trust, UK TrialPROMISE-meso ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:04
Frontline ipilimumab/nivolumab improves OS in advanced NCLSC Presented ByProf. Solange Peters, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland TrialPhase 3, CheckMate-227 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 22:05
First-line osimertinib significantly lengthens OS in NSCLC Presented ByProf. Suresh Ramalingam, Emory University, Atlanta, USA TrialPhase 3, FLAURA ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 21:05
Liquid biopsy to decide the best treatment for NSCLC Presented ByDr Shirish Gadgeel, University of Michigan, USA TrialPhase 2, BFAST ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:05
Long-term data from CheckMate 067 Presented ByProf. James Larkin, Royal Marsden NHS Foundation Trust, London, UK TrialPhase 3, CheckMate 067 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:06
Adjuvant nivolumab provides benefit Presented ByProf. Jeffrey S. Weber, NYU Langone Medical Center, New York City, USA TrialPhase 3, CheckMate 238 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 22:15
Nivolumab+ipilimumab superior to monotherapy for melanoma brain metastases Presented ByProf. Georgina Long, Melanoma Institute Australia, Sydney, Australia TrialABC ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:15
Preoperative chemotherapy for colon cancer Presented ByProf. Dion Morton, University of Birmingham, UK TrialFOxTROT, phase 2/3 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:20
Nivolumab improves OS in advanced oesophageal cancer Presented ByProf. Byoung Chul Cho, Yonsei University College of Medicine, South Korea TrialPhase 3, ATTRACTION-3 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 22:19
Liquid biopsy identifies relapse in patients with colorectal cancer after surgery Presented ByProf. Julien Taieb, Hopital European Georges Pompidou, France TrialPhase 3, IDEA-FRANCE ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 21:17
In hepatocellular carcinoma, CheckMate 459 misses OS endpoint, but some interesting trends emerge Presented ByDr Thomas Yau, University of Hong Kong, China TrialPhase 3, CheckMate 459 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 20:21
Heavily pre-treated GIST: ripretinib improves PFS Presented ByProf. Margaret von Mehren, Fox Chase Cancer Center, USA TrialPhase 3, INVICTUS ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 19:21
FGFR2+ cholangiocarcinoma: pemigatinib active as second-line treatment Presented ByProf. Antoine Hollebecque, Gustave Roussy Cancer Center, France TrialPhase 2, FIGHT-202 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 18:21
IDH1+ cholangiocarcinoma: phase 3 results show improved PFS Presented ByDr Ghassan Abou-Alfa, Memorial Sloan-Kettering Cancer Center, New York, USA TrialPhase 3, ClarIDHy ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 17:22
Advanced colorectal cancer and BRAF mutations: triplet combination improves survival Presented ByProf. Scott Kopetz, MD Anderson Cancer Center, Houston, USA TrialPhase 3, BEACON CRC ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:22
25% reduction in the risk of death in patients with nmCRPC treated with apalutamide Presented ByProf. Matthew Smith, Massachusetts General Hospital, Boston, USA TrialPhase 3, SPARTAN ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:23
Enfortumab vedotin and pembrolizumab in advanced bladder cancer: initial results Presented ByProf. Christopher Hoimes, Case Comprehensive Cancer Center, Cleveland, USA TrialPhase 1, EV-103 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 22:23
PARP inhibition in selected patients slows progression on advanced prostate cancer Presented ByProf. Maha Hussain, Northwestern University, Chicago, USA TrialPhase 3, PROfound ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 21:24
PFS extension with immunotherapy + chemotherapy in urothelial cancer Presented ByDr Enrique Grande, MD Anderson Cancer Centre Madrid, Spain TrialIMvigor130 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 21:24
Third-line in mCRPC: CARD trial Presented ByProf. Ronald De Wit, Erasmus University Rotterdam, the Netherlands TrialCARD ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 20:24
Prostate cancer: spare radiotherapy after surgery Presented ByProf. Chris Parker, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, UK TrialRADICALS-RT ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 18:24
Novel mode of action for kidney cancer treatment Presented ByProf. Eric Jonasch, MD Anderson Cancer Center, Houston, USA ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:24
Ovarian cancer patients benefit from combined maintenance therapy Presented ByProf. Isabelle Ray-Coquard, Université Claude Bernard, Lyon, France TrialPhase 3, PAOLA-1/ENGOT-ov25 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:25
Combination of PARP inhibition plus chemotherapy in ovarian cancer Presented ByRobert Coleman, University of Texas, MD Anderson Cancer Center, Houston, USA TrialPhase 3, VELIA ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 22:26
PFS benefit with niraparib as first-line maintenance in ovarian cancer Principal InvestigatorProf. Antonio González Martín, Clinica Universidad de Navarra, Spain TrialPhase 3, PRIMA/ENGOT-OV26/GOG-3012 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:26
Ceritinib in ALK+ NSCLC brain metastases Presented ByDr Laura Quan Man Chow, University of Texas at Austin, USA TrialPhase 2, ASCEND-7 ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:28
Adding bevacizumab to temozolomide-based therapy in neuroblastoma TrialPhase 2, BEACON-Neuroblastoma ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:29
Mixed data: AMG 510 in tumours with KRASG12C Presented ByProf. Ramaswamy Govindan, Washington University, St Louis, USA ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 23:30
DNA profiling of carcinoma of unknown primary should inform treatment Presented ByProf. Karim Fizazi, University of Paris Sud, France TrialGEFCAPI 04, CUPISCO ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 22:30
Larotrectinib: safe and effective in TRK fusion-positive tumours Presented ByDr David Hyman, Memorial Sloan Kettering Cancer Center, New York, USA TrialSCOUT, NAVIGATE ConferenceESMO 2019 TypePeer-reviewed article 26 November 2019 14:30