ASCO 2019 Archives - Medical Conferences

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American Society of Clinical Oncology 31 May – 4 June 2019, Chicago, USA

Featured articles

Letter from the Editors

Editor

Dr Erlinda Maria Gordon, Dr Sant P. Chawla

Conference

ASCO 2019

15 July 2019 15:30

Endocrine therapy plus ribociclib yields overall survival advantage in HR+/HER2-negative breast cancer

Presented By

Dr Sara A. Hurvitz, University of California, Los Angeles, Jonsson Comprehensive Cancer Centre

Trial

Phase 3, MONALEESA-7

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 15:00

Online First

Breast Cancer

Endocrine therapy plus ribociclib yields overall survival advantage in HR+/HER2-negative breast cancer

Presented By

Dr Sara A. Hurvitz, University of California, Los Angeles, Jonsson Comprehensive Cancer Centre

Trial

Phase 3, MONALEESA-7

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 15:00

Biomarker analysis predicts response to adjuvant trastuzumab, pertuzumab in HER2+ breast cancer

Presented By

Dr Ian E. Krop, Dana-Farber Cancer Institute, USA

Trial

Phase 3, APHINITY

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 14:00

ImPassion130 brings breast cancer into the immunotherapy era

Trial

Phase 3, ImPassion130

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 11:27

Melanoma

Nivolumab-mediated adverse events are independent of efficacy in resected advanced melanoma

Presented By

Prof. Mario Mandalà, Papa Giovanni XXIII Cancer Centre Hospital, Bergamo, Italy

Trial

CheckMate 238

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 23:18

Long term quality of life with nivolumab, or in combination (ipilimumab) in advanced melanoma

Trial

Phase 3, CheckMate 067

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 12:45

Kidney Cancer

Classification of metastatic renal cell carcinoma patients in immunotherapy era and positive responses for sarcomatoid tumours

Presented By

Prof. Bernhard Escudier, Gustave Roussy Cancer Campus, Paris, France

Trial

CheckMate 214

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 12:49

Sarcoma

Olaratumab trial in soft tissue sarcoma fails to meet overall survival endpoint

Presented By

Dr William D. Tap, Memorial Sloan Kettering Cancer Centre, USA

Trial

Phase 3, ANNOUNCE

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 13:46

Gastrointestinal Cancers

FOLFOXIRI plus bevacizumab an option for patients with mCRC and poor prognosis

Presented By

Dr Javier Sastre, Hospital Clínico San Carlos, Spain

Trial

Phase 3, VISNU-1

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 23:53

KEYNOTE-062: Pembrolizumab combination fails to improve survival in gastric/GEJ cancer

Presented By

Dr Josep Tabernero, Vall d’Hebron University Hospital, Spain

Trial

Phase 3, KEYNOTE-062

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 22:56

Neoadjuvant chemotherapy as a potential treatment option in colon cancer

Presented By

Dr Matthew T. Seymour, National Institute for Health Research Clinical Research Network, England

Trial

FOxTROT

Type

Peer-reviewed article

15 July 2019 21:58

Laparascopic surgery; less morbidity, same survival benefits as open surgery in colorectal cancer with liver metastases

Presented By

Dr Åsmund Avdem Fretland, Oslo University Hospital, Norway

Trial

OSLO-COMET

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 20:01

Maintenance olaparib improved PFS in patients with BRCA+ pancreatic cancer

Presented By

Dr Hedy L. Kindler, The University of Chicago, USA

Trial

Phase 3, POLO

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 14:07

Hematologic Malignancies

Daratumumab a promising treatment option for transplant-eligible multiple myeloma

Presented By

Dr Philippe Moreau, University Hospital Hôtel-Dieu, France

Trial

Phase 3, CASSIOPEIA

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 23:14

Rituximab/lenalidomide regimen shows clinical benefit in non-hodgkin lymphoma trials

Trial

MAGNIFY, AUGMENT

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 14:17

Paediatric Oncology

Entrectinib produces rapid and durable responses in children with refractory CNS and solid tumours

Presented By

Dr Giles W. Robinson, St. Jude Children’s Research Hospital, USA

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 14:20

Head and Neck Cancer

Ado-trastuzumab emtansine a potential new treatment option for HER2-amplified advanced salivary gland cancer

Presented By

Dr Bob T. Li, Memorial Sloan Kettering Cancer Centre, USA

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 23:13

Sentinel lymph node biopsy shows promise for early oral cancer

Presented By

Dr Yasuhisa Hasegawa, Asahi University Hospital, Japan

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 15:20

Genitourinary Cancer - Prostate Cancer

Enzalutamide offers survival advantage over other NSAAs in mHSPC

Presented By

Dr Christopher Sweeney, Dana-Farber Cancer Institute, USA

Trial

ENZAMET, TITAN

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 23:26

Benefits seen with apalutamide plus ADT in metastatic castration-sensitive prostate cancer

Presented By

Dr Kim N. Chi, BC Cancer Agency, Canada

Trial

Phase 3, TITAN

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 22:28

Enfortumab vedotin highly active in previously treated advanced urothelial carcinoma

Presented By

Dr Daniel P. Petrylak, Yale School of Medicine, USA

Trial

EV-201, EV-301

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 13:42

Multiple Myeloma

Anti-CD38 antibody isatuximab improves treatment response, PFS in R/R multiple myeloma

Presented By

Dr Paul G. Richardson, Dana-Farber Cancer Institute/Harvard Medical School, USA

Trial

Phase 2, ICARIA-MM

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 13:53

Lung Cancer

Neoadjuvant nivolumab/ipilimumab shows promise in resectable NSCLC

Presented By

Dr Tina Cascone, University of Texas MD Anderson Cancer Centre, USA

Trial

NEOSTAR

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 23:59

Overcoming the challenges of immunotherapy in non–small cell lung cancer

Presented By

Dr Sarah B. Goldberg, Dr Melissa Lynne Johnson, Dr Alexander Chi

Trial

PACIFIC, KEYNOTE-024, KEYNOTE-189

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 22:04

Repotrectinib shows encouraging safety, efficacy for patients with ROS1+ NSCLC

Presented By

Dr Byoung Chul Cho, Yonsei Cancer Centre, South Korea

Trial

TRIDENT-1

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 21:15

Pembrolizumab monotherapy leads to 5-year survival in some patients with NSCLC

Presented By

Dr Edward B. Garon, David Geffen School of Medicine, USA

Trial

Phase 1, KEYNOTE-001

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 20:17

Novel RET inhibitor BLU-667 offers promise for RET+ advanced NSCLC

Presented By

Dr Justin F. Gainor, Massachusetts General Hospital, USA

Trial

Phase 1, ARROW

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 19:23

Lurbinectedin shows promise as second-line therapy for SCLC

Presented By

Dr Luis G. Paz-Ares, Hospital Universitario 12 de Octubre, Spain

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 18:27

Early results from TAK-788 in NSCLC with EGFR exon 20 insertions

Presented By

Dr Gregory Riely, Memorial Sloan Kettering Cancer Centre, USA

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 13:31

Developmental Therapeutics - Immunotherapy

IL-6 and C-reactive protein as potential biomarkers for checkpoint inhibition

Presented By

Dr Jeffrey S. Weber, Laura and Isaac Perlmutter Cancer Centre, USA

Trial

CheckMate-064, CheckMate-066, CheckMate-067

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 23:55

First-in-human study shows IL1RAP-targeting drug safe in solid tumours

Presented By

Dr Ahmad Awada, Institut Jules Bordet, Belgium

Conference

ASCO 2019

Type

Peer-reviewed article

15 July 2019 13:58

Featured articles

CONTENTS

Online First

Breast Cancer

Melanoma

Kidney Cancer

Sarcoma

Gastrointestinal Cancers

Hematologic Malignancies

Paediatric Oncology

Head and Neck Cancer

Genitourinary Cancer - Prostate Cancer

Multiple Myeloma

Lung Cancer

Developmental Therapeutics - Immunotherapy