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Oral prevention of skin cancer

Presented By
Dr Yolanda Gilaberte Calzada, Miguel Servet University Hospital, Spain
Conference
EADV 2020
Multiple studies have been conducted to evaluate the potential role of chemoprevention of skin cancer; Dr Yolanda Gilaberte Calzada (Miguel Servet University Hospital, Spain) provided a thorough overview of findings to date [1].   The most robust evidence is for the use of acitretin; current guidelines recommend its use for the prevention of squamous cell carcinoma in organ transplant recipients. An observational study of nearly 44,000 Australians divided subjects into groups according to risk, with high-risk defined as having a history of skin cancer excisions or >5 actinic keratosis (AK) lesions, and low-risk defined as having no history of skin cancer excisions and ≤5 AK lesions. At 3-year follow up, those in the high-risk group who took non-steroidal anti-inflammatory drugs (NSAIDs) at least weekly showed a decreased risk of basal cell carcinoma but not squamous cell carcinoma; those who took aspirin less than weekly showed a decreased risk o...


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