https://doi.org/10.55788/755bf764
Dr Daniel Ignatiuk (Cincinnati Children’s Hospital, OH, USA) presented a retrospective study analysing OSA risk factors documented in a 10-year cohort of paediatric patients with PH at the Cincinnati Children’s Hospital, between January 2010 and August 2020 [1]. Identified were 403 patients aged 0–21 years who underwent diagnostic polysomnogram (PSG), including 89 patients with a documented diagnosis of PH (median age 3.6 years; range 9 days to 17.6 years). These 89 patients were sub-classified based on their PH group: group 1 (n=25; 28.1%), group 3 (n=31; 34.8%), and group 1/3 for patients meeting both group 1 and 3 criteria (n=33; 37.1%). Group 2 consisted of only 2 patients and was excluded from the analysis due to the low number.
Diagnosed sleep disorders included OSA (n=79; 88.8%), central sleep apnoea (n=11; 12.4%), hypoventilation (n=6; 6.7%), non-apnoeic hypoxaemia (n=28; 31.5%), and periodic limb movement disorder (n=5, 5.6%). OSA risk was increased with a diagnosis of trisomy 21 (RR 1.24; 95% CI 1.09–1.42; P<0.05).
However, OSA risk was decreased in group 1 compared with group 1/3 PH (RR 0.84; 95% CI 0.71–0.99; P<0.05) or group 3 PH (RR 0.81; 95% CI 0.68–0.96; P<0.05), and no difference in OSA risk between group 1 and group 3 PH was observed.
The take-home message for this study was that OSA was diagnosed in a majority of paediatric patients, most notably in patients with trisomy 21 or PH classification meeting both group 1 and 3 criteria. “Our research supports routine screening for OSA in this population, especially,” concluded Dr Ignatiuk.
- Ignatiuk D, et al. Risk for Obstructive Sleep Apnea in Pediatric Patients with Pulmonary Hypertension. Session A68, ATS International Conference 2022, San Francisco, CA, USA, 13–18 May.
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Table of Contents: ATS 2022
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Letter from the Editor
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POISE-3: Tranexamic acid for non-cardiac surgery
Obstructive sleep apnoea in most children with pulmonary hypertension
No screening evidence for COPD
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