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Predicting MCI and dementia by assessing worrying about memory

Presented By
Prof. Frank Jessen, University Hospital of Cologne, Germany
Conference
ECNP 2020
Trial
Cohort study, AgeCoDe
Worrying about memory was associated with an increased risk of mild cognitive impairment (MCI) and dementia in individuals with subjective cognitive decline in a study based on longitudinal data from the AgeCoDe study [1]. This worrying was associated with abnormal β-amyloid in participants with MCI related to the severity of their subjective cognitive decline [2]. Prof. Frank Jessen (University Hospital of Cologne, Germany) presented data from the German AgeCoDe, an ongoing, multicentre study on ageing, cognition, and dementia [1]. This is a population-representative cohort aiming to identify risk factors of dementia. The present study from the AgeCoDe cohort included data from over 3,000 participants with an average age at baseline of 75 years; nobody had dementia [1]. One of the findings of the present study showed that cognitively healthy participants (n=2,423) with a subjective cognitive decline have a hazard ratio (HR) of 3.04 for developing A...


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