Home > Neurology > Personalizing rTMS target sites likely to improve antidepressant effects

Personalizing rTMS target sites likely to improve antidepressant effects

Journal
JAMA Psychiatry
Reuters Health - 01/12/2020 - Patients with depression will have a stronger response to repetitive transcranial magnetic stimulation (rTMS) when it's delivered to a personalized target, new findings suggest. In 26 patients with major depressive disorder (MDD) who had already undergone rTMS, the closer the clinically targeted site was to a subsequently determined personalized target, the better the outcome, Dr. Robin F. H. Cash of The University of Melbourne, in Australia, and colleagues found. "Our work provides very strong evidence that individual clinical benefit to following brain stimulation is determined by brain connectivity (pathways of communication) between the prefrontal stimulation target and deeper regions of the brain that are involved in emotional regulation," Dr. Cash told Reuters Health in an email. "We developed new methodology which can pinpoint the optimal stimulation target based on an individual's brain scan with unprecedented accuracy." ...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on