Home > Neurology > AAN 2022 > COVID-19 > Cognitive, EEG, and MRI features in COVID-19 survivors

Cognitive, EEG, and MRI features in COVID-19 survivors

Presented By
Dr Giordano Cecchetti, Vita-Salute San Raffaele University, Italy
Conference
AAN 2022
Doi
https://doi.org/10.55788/dcba1289
For the first time, long-term neurocognitive and neurophysiological consequences of COVID-19 have been assessed. Patients showed interrelated cognitive, EEG, and MRI alterations 2 months after hospital discharge. Cognitive and EEG findings improved at 10 months. Dysgeusia and hyposmia during acute COVID-19 were related to increased vulnerability of memory over time. Cognitive impairment has been reported in 81% and 21% of patients at 3 and 6 months after SARS-CoV-2 infection, respectively [1,2]. Psychiatric disturbance is present in 56% after 1 month and in 25% after 6 months [3,4]. Proposed pathogenic contributors are direct cerebral viral invasion and cellular damage, systemic inflammation through cytokine release, and cerebral microvascular changes [5]. Neuropathological studies have shown pronounced microglia activation and microthrombosis within white matter, mainly in the brain stem. Concerns about long-lasting neurological consequences of ...


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