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Asymptomatic SARS-CoV-2 infection common in IBD patients

Reuters Health - 04/09/2020 - As many as one in five patients with inflammatory bowel disease (IBD) under biologic treatment have evidence of mild or asymptomatic SARS-CoV-2 infection, researchers in Italy report. Patients with IBD, including those on biologic treatment, appear to have an uneventful course during the SARS-CoV-2 pandemic, but the rate of exposure of these patients to SARS-CoV-2 remains unknown. Dr. Lorenzo Norsa and colleagues at Papa Giovanni XXIII Hospital, in Bergamo, assessed the seroprevalence of COVID-19 among all 103 adult and pediatric patients with IBD undergoing biologic therapy at their center during the Italian COVID-19 outbreak. All symptoms suggestive of SARS-CoV-2 infection reported by these patients were mild, and none required hospitalization for COVID-19. Of the 90 patients who underwent serologic testing, 19 (21%) were positive for IgG, IgM, or both, the authors report in Gastroenterology. Eleven of these 19 pa...

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