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Advanced colorectal neoplasia risk seen before age 50

Journal
Gastroenterology

Reuters Health - 21/06/2021 - Average-risk individuals who undergo screening colonoscopy at ages 45 to 49 have a risk of early-age onset colorectal neoplasia that is similar to people in the 50-59 age group and warrants screening at younger ages, a systematic review and meta-analysis suggests.

Researchers examined data from 17 studies with a total of 51,811 average-risk individuals who underwent screening colonoscopy. The main focus of the study was on early-age onset of colorectal neoplasia, which researchers defined as cases before age 50.

Overall, the pooled rate of early-age onset colorectal neoplasia was 13.7% and the pooled rate of early-age onset advanced colorectal neoplasia was 2.2%.

"The rates of colorectal cancer have been increasing in individuals under age 50 for the last several decades, thus, we are not surprised to learn that advanced colorectal neoplasia rates in 45-49 year olds are similar to those observed in 50-59 year olds," said senior s...



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