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Suicidality and psychological adverse events tied to finasteride

JAMA Dermatology
Reuters Health - 11/11/2020 - Use of finasteride to treat hair loss is associated with increased risk of suicidality and psychological adverse events, a new study suggests. An analysis of data in the World Health Organization's global database of individual case safety reports turned up more than 350 reports of suicidality and nearly 3,000 reports of anxiety and depression associated with finasteride, according to the results published in JAMA Dermatology. "We found a signal for . . . suicidal ideation among younger men taking the medication for hair loss," said study coauthor Dr. Quoc Dien Trinh, a urologist and director of clinical operations in the division of urological surgery at Brigham and Women's Hospital in Boston. "I would caution readers not to over-interpret the findings of our exploratory analysis," Dr. Trinh said in an email. "Patients should be aware of this potential side effect and speak to their prescribing doctor if they have concerns."...

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