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Mohs surgery may not boost survival over standard excision of melanomas on trunk, extremities

Journal
JAMA Dermatology
Reuters Health - 29/10/2020 - Compared with wide local excision (WLE), Mohs micrographic surgery (MMS) does not appear to increase overall survival in patients with trunk or extremity melanomas, according to a retrospective study. "In contrast to our previous work, which demonstrated a statistically significant survival benefit for MMS over WLE for all-stage cutaneous melanoma of the head and neck, this study failed to demonstrate a statistically significant difference in survival outcomes between MMS and WLE treatment modalities when trunk and extremity tumors were evaluated," Dr. Addison M. Demer of the University of Minnesota, in Minneapolis, told Reuters Health by email. MMS is gaining popularity in the U.S. and is associated with improved overall survival (OS) for some types of melanomas, Dr. Demer and his colleagues note in JAMA Dermatology. However, they add, "It remains unclear if there is a survival advantage . . . when it is used for the treatment of all-s...


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