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Early emollient use may reduce AD risk in infants

Presented By
Prof. Alan Irvine, Trinity College Dublin, Ireland
EADV 2022
Infants with a high risk to develop atopic dermatitis (AD) that started an 8-week intervention with emollients directly after birth had a significant risk reduction for AD, showed the STOP AD study. Babies treated twice daily with the emollient maintained AD-free skin for a significantly longer period in the first 12 months than the control group. Irish researchers set up the single centre, investigator-blinded STOP AD study (NCT03871998) that tested short-term emollient use for its capacity to prevent AD [1]. The 321, randomised, high-risk infants with a family history of AD were included from birth to ≤4 days. The intervention arm of the study immediately started an 8-week course with a ceramide dominant emollient at a dose of about 7 fingertip units applied twice daily. The control arm infants received standard...

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