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Chronic spontaneous urticaria: hives, wheals & biomarkers

Presented By
Prof. Ana Giménez-Arnau, Autonomous University of Barcelona, Spain
EADV 2020
Chronic spontaneous urticaria (CSU) has numerous biomarkers. Some of these biomarkers appear to be useful in monitoring disease activity and severity as well as in predicting treatment response. CSU is a mast cell-driven disease characterised by the presence and recurrence of wheals and angioedema [1]. “In patients with high disease severity, angioedema, positivity of the autologous serum skin test [autoreactivity] or a combination with physical urticaria, the overall duration of CSU tends to be longer,” said Prof. Ana Giménez-Arnau (Autonomous University of Barcelona, Spain). In her presentation, Prof. Giménez-Arnau shed light on the long list of potential biomarkers. Bench-to-bedside Prof. Giménez-Arnau listed a seemingly limitless list of potential biomarkers including: TAT, fibrinogen, FVIIa, FXIIa, FVIII, FIX, FII, C-reactive protein (CRP), vitamin D, B12, prolactin, DHEA-S, cortisol, histamine, anti-IgE, IgG, IFNγ, TNF, histamine, try...

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