A new method of treatment application that has recently been investigated is thermomechanical drug delivery into keloid skin [2]. In a retrospective study, 7 patients were given a mix of triamcinolone acetonide (TAC) plus 5-fluorouracil in a ratio of 1:9 after skin treatment with a titanium tip heated to 400°C. After 8 topical thermal ablations (1 ablation performed every 2-3 weeks), mean keloid Vancouver Scar Scale score was significantly reduced from 8.6 ± 1.2 at baseline to 5 ± 2.7 (P=0.001) [2].
“As a principle after surgery of a keloid of the earlobe, the wound should be closed without tension,” said Dr Somesh Gupta (All India Institute of Medical Sciences, India) in his lecture on less explored and experimental treatments for keloids. Injections, pressure, or a combination of both are possible options to avoid recurrence after surgery, according to Dr Gupta [1]. “In general, we do not give injections because they are painful. We often prefer to use pressure earrings using neodymium magnetic discs,” he continued. This easy and economically available possibility should be applied for about 5-6 hours a day, in order to avoid necrosis.
- Gupta S. 24th World Congress of Dermatology, 10-15 June 2019, Milan, Italy.
- Artzi O, et al. Dermatol Ther. 2019;9:321-326.
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Table of Contents: WCD 2019
Featured articles
Letter from the Editor
Insights into pathogenesis of AD define novel therapeutic targets
Treating Psoriasis in 2019
Choosing the right biologic in psoriasis
Registries – an important research tool in biologics
Atopic Dermatitis – What is New
Insights into pathogenesis of AD define novel therapeutic targets
Combinations are hot in AD treatment
Dermal Reactions to Systemic Drugs
Cutaneous adverse events due to EGFR inhibitors
Management strategies for drug-induced mucositis
Skin toxicity of immune checkpoint inhibitors
Lupus Erythematosus Today
New targets and biologics for cutaneous lupus erythematosus
Novel lupus classification will aid future research
Hidradenitis Suppurativa
Various guidelines with much overlap
Antibiotics in hidradenitis suppurativa
Biologicals beyond TNF blockade
Small Molecules – What to Expect
Novel treatment options for many dermatologic indications
Long awaited oral therapy for moderate-to-severe AD
Novel treatment options in alopecia areata and vitiligo
Optimising the Management of Keloids
Keloids: a faulty switch in wound healing?
What the future of keloid treatment could hold
Malignant Melanoma – Advances in Management
Will malignant melanoma become a curable disease?
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