Less explored therapies include procedures with injection-free drug delivery that may gain further importance in the armamentarium for keloid treatment .
A new method of treatment application that has recently been investigated is thermomechanical drug delivery into keloid skin . In a retrospective study, 7 patients were given a mix of triamcinolone acetonide (TAC) plus 5-fluorouracil in a ratio of 1:9 after skin treatment with a titanium tip heated to 400°C. After 8 topical thermal ablations (1 ablation performed every 2-3 weeks), mean keloid Vancouver Scar Scale score was significantly reduced from 8.6 ± 1.2 at baseline to 5 ± 2.7 (P=0.001) .
“As a principle after surgery of a keloid of the earlobe, the wound should be closed without tension,” said Dr Somesh Gupta (All India Institute of Medical Sciences, India) in his lecture on less explored and experimental treatments for keloids. Injections, pressure, or a combination of both are poss...
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