https://doi.org/10.55788/6c0e1a91
Thank you for your interest in this edition of Medicom’s Conference Report covering the European Society of Cardiology Congress 2024, held in London, England. This year’s meeting covered a wide array of topics, from novel treatments for heart failure to unexpected results from studies with novel anticoagulants. There were fresh perspectives on the utility of beta-blockers in patients with coronary artery disease, polypill therapy, novel uses of AI, and new treatments for amyloid.
In the following pages, you will find new data for the novel non-steroidal MRA finerenone in heart failure with preserved ejection fraction from the FINEARTS-HF trial; unexpected findings from the early termination of the OCEANIC-AF trial; and data with regard to the effects of beta-blocker therapy in coronary artery disease. There is much more than this with comprehensive coverage of over 20 presentations and 4 new guidelines.
I hope you find the summaries included informative, balanced, and inspiring as we look forward to great promise in the scientific innovation that will improve outcomes for patients suffering from cardiovascular and cardiometabolic diseases.
Sincerely,
Prof. Marc Bonaca
Biography
Marc P. Bonaca, MD, MPH, is a Cardiologist and Vascular Medicine Specialist who serves as the Executive Director of CPC Clinical Research and CPC Community Health at the University of Colorado Anschutz Medical Campus. He is the Director of Vascular Research and a Professor of Medicine at the University of Colorado School of Medicine and the inaugural holder of the William R. Hiatt Endowed Chair in Cardiovascular Research.
Dr Bonaca earned his medical degree from the University of Connecticut School of Medicine and his Masters in Public Health at Harvard University. He served as a Medical House Officer at Brigham and Women’s Hospital and Harvard Medical School. After completion of his training, he joined the faculty of the Cardiovascular Division and Vascular Medicine section of Brigham and Women’s Hospital and Harvard Medical School and became an Investigator at the TIMI Study Group.
Dr Bonaca’s research focus is on ischemic risk in patients with atherosclerotic vascular disease, risk prediction, and risk modification through the use of pharmacologic and biologic therapies. His key areas of interest include patients with peripheral artery disease, polyvascular disease and diabetes with a focus on the breadth of risk including ischemic limb outcomes, microvascular complications and major adverse cardiovascular events.
Conflict of Interest Statement:
Dr Bonaca is the Executive Director of CPC, a non-profit academic research organization affiliated with the University of Colorado, that receives or has received research grant/consulting funding between August 2021 and present from: Abbott Laboratories, Agios Pharmaceuticals, Inc., Alexion Pharma, Alnylam Pharmaceuticals, Inc., Amgen Inc., Angionetics, Inc., Anthos Therapeutics, ARCA Biopharma, Inc., Array BioPharma, Inc., AstraZeneca and Affiliates, Atentiv LLC, Audentes Therapeutics, Inc., Bayer and Affiliates, Beth Israel Deaconess Medical Center, Better Therapeutics, Inc., Boston Clinical Research Institute, Bristol-Meyers Squibb Company, Cambrian Biopharma, Inc., Cardiol Therapeutics Inc., CellResearch Corp., Cleerly Inc., Cook Regentec LLC, CSL Behring LLC, Eidos Therapeutics, Inc., EP Trading Co. Ltd., EPG Communication Holdings Ltd., Epizon Pharma, Inc., Esperion Therapeutics, Inc., Everly Well, Inc., Exicon Consulting Pvt. Ltd., Faraday Pharmaceuticals, Inc., Foresee Pharmaceuticals Co. Ltd., Fortress Biotech, Inc., HDL Therapeutics Inc., HeartFlow Inc., Hummingbird Bioscience, Insmed Inc., Ionis Pharmaceuticals, IQVIA Inc., Janssen and Affiliates, Kowa Research Institute, Inc., Kyushu University, Lexicon Pharmaceuticals, Inc., Medimmune Ltd., Medpace, Merck & Affiliates, Nectero Medical Inc., Novartis Pharmaceuticals Corp., Novo Nordisk, Inc., Osiris Therapeutics Inc., Pfizer Inc., PhaseBio Pharmaceuticals, Inc., PPD Development, LP, Prairie Education and Research Cooperative, Prothena Biosciences Limited, Regeneron Pharmaceuticals, Inc., Regio Biosciences, Inc., Saint Luke’s Hospital of Kansas City, Sanifit Therapeutics S.A., Sanofi-Aventis Groupe, Silence Therapeutics PLC, Smith & Nephew plc, Stanford Center for Clinical Research, Stealth BioTherapeutics Inc., State of Colorado CCPD Grant, The Brigham & Women's Hospital, Inc., The Feinstein Institutes for Medical Research, Thrombosis Research Institute, University of Colorado, University of Pittsburgh, VarmX, Virta Health Corporation, Worldwide Clinical Trials Inc., WraSer, LLC, and Yale Cardiovascular Research Group.
Dr. Bonaca receives support from the AHA SFRN under award numbers 18SFRN3390085 (BWH-DH SFRN Center) and 18SFRN33960262 (BWH-DH Clinical Project).
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Table of Contents: ESC 2024
Featured articles
Meet the Expert: Dr Abdullahi Mohamed on Iron Deficiency in Patients with HF
2024 ESC Guidelines in a Nutshell
Guidelines for the management of elevated blood pressure and hypertension
Guidelines for the management of chronic coronary syndromes
Guidelines for the management of atrial fibrillation
Guidelines for the management of peripheral artery and aortic diseases
Crossing Borders in Arrhythmia
EPIC-CAD: What is the best antithrombotic approach in high-risk AF plus stable CAD?
OCEANIC-AF: Asundexian inferior to apixaban for ischaemic stroke prevention in AF
MIRACLE-AF: Elegant solution to improve AF care in rural China
SUPPRESS-AF: What is the value of adding LVA ablation to PVI in AF?
Clever Ideas for Coronary Artery Disease
ABYSS: Can beta-blocker safely be interrupted post-MI?
SWEDEGRAFT: Can a no-touch vein harvesting technique improve outcomes in CABG?
Bioadaptor meets expectations in reducing target lesion failures in coronary artery disease
REC-CAGEFREE I: Can we avoid permanent stenting with drug-coated balloons?
OCCUPI: OCT-guided PCI improves outcomes in complex CAD
Highway to Hypertension Control
Low-dose 3-drug pill GMRx2 shows promise in lowering BP
Is administering BP medication in the evening better than in the morning?
VERONICA: Improving BP control in Africa with a simple strategy
High-end Trials in Heart Failure
FINEARTS-HF: Finerenone improves outcomes in heart failure with preserved ejection fraction
MRAs show varied efficacy in heart failure across ejection fractions
MATTERHORN: Transcatheter repair matches surgery for HF with secondary mitral regurgitation
RESHAPE-HF2: Not a “tie-breaker” for TEER in heart failure
Practical Gains in Screening and Diagnostics
STEEER-AF: Shockingly low adherence to ESC atrial fibrillation guidelines
SCOFF: To fast or not to fast, that’s the question
WESTCOR-POC: Point-of-care hs-troponin testing increases emergency department efficiency
PROTEUS: Can AI improve decision-making around stress echocardiography?
RAPIDxAI: Can AI-augmented chest pain assessment improve cardiovascular outcomes?
Miscellaneous Achievements in Cardiology
HELIOS-B: Vutrisiran candidate for SoC in ATTR cardiomyopathy
Does RAS inhibitor discontinuation affect outcomes after non-cardiac surgery?
Novel approach to managing severe tricuspid regurgitation proves its value
NOTION-3: TAVI plus PCI improves outcomes in CAD plus severe aortic stenosis
RHEIA: TAVI outperformed surgery in women with aortic stenosis
Related Articles
November 7, 2024
HELIOS-B: Vutrisiran candidate for SoC in ATTR cardiomyopathy
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